Pitavastatin

[Laxman3221]

Whew, this thread had a good run before the anti-science brigade showed up.



LOL. Nobody is anti science here but some don't blindly beleive what pharmacutical companies put out or medical associations.

Take some vioxx or your 8th booster is you believe the Rx companies when they say its safe and effective. They would never hide data or manipulate studies that lead to the death of 60k people. Would they? I mean kill over 60k people and still profit billions.

The American Heart Association (AHA)
initially opposed a Texas bill that would ban the purchase of junk food with SNAP benefits due to concerns about potential impacts on program participation and population health. The organization stated the bill needed to ensure it did not reduce hunger and that public education was a better approach than nutritional restrictions. This opposition drew criticism due to the AHA's conflict of interest, as it receives funding from the food industry. The AHA has since reversed its stance and now supports removing sugary drinks from SNAP

Junk food is so healthy and we don't want out sugar daddy's losing money! As they say follow the money.

 

[Ghoul]

Whew, this thread had a good run before the anti-science brigade showed up.



LOL. Nobody is anti science here but some don't blindly beleive what pharmacutical companies put out or medical associations.

Take some vioxx or your 8th booster is you believe the Rx companies when they say its safe and effective. They would never hide data or manipulate studies that lead to the death of 60k people. Would they? I mean kill over 60k people and still profit billions.

The American Heart Association (AHA)
initially opposed a Texas bill that would ban the purchase of junk food with SNAP benefits due to concerns about potential impacts on program participation and population health. The organization stated the bill needed to ensure it did not reduce hunger and that public education was a better approach than nutritional restrictions. This opposition drew criticism due to the AHA's conflict of interest, as it receives funding from the food industry. The AHA has since reversed its stance and now supports removing sugary drinks from SNAP

Junk food is so healthy and we don't want out sugar daddy's losing money! As they say follow the money.

LDL is the primary driver of cardiovascular disease, treatments that lower is save lives. It's beyond dispute backed by an overwhelming body of evidence.

It's not "blindly" believing anything. Not "Big Pharma", "Big Medicine", or any other grand conspiracy supposedly intent on getting people needlessly hooked on cheap generic meds that cost less than $20 a year.

 

[newguy2]

LDL is the primary driver of cardiovascular disease, treatments that lower is save lives. It's beyond dispute backed by an overwhelming body of evidence.

It's not "blindly" believing anything. Not "Big Pharma", "Big Medicine", or any other grand conspiracy supposedly intent on getting people needlessly hooked on cheap generic meds that cost less than $20 a year.

There's always multiple ways to look at data.

 

[keengkong]

There's always multiple ways to look at data.

That’s why I don’t eat healthy food; I look who stands to profit by claiming some food is healthier than others. Using the same reasoning, I never exercise. Nor do I bathe; I look at how much the water company has to profit off the cleanliness myth.

 

[Avies48]

That’s why I don’t eat healthy food; I look who stands to profit by claiming some food is healthier than others. Using the same reasoning, I never exercise. Nor do I bathe; I look at how much the water company has to profit off the cleanliness myth.

Well fucken a!

Chose ir food wisely… use a creek, and start up jogging…

All about choices haha

 

[hexagonal]

Whew, this thread had a good run before the anti-science brigade showed up.



LOL. Nobody is anti science here but some don't blindly beleive what pharmacutical companies put out or medical associations.

Y'all are posting random nonsense videos from unserious people without any particular knowledge or expertise in the subject making claims counter to massive quantities of data gathered across decades and millions of data points without any significant evidence of their own to back up their claims. It is deeply anti-science.

Any individual study might be impacted by bias. As you build up hundreds of studies that all point in the same direction, it is less and less likely there is any bias there. Also, these studies have the data. They have the methodology. Instead of just going "BIG PHARMA! GOVERNMENT! RESEARCHERS! BIAS! COLLUSION!" maybe actually point out the actual flaws in the studies?

Take some vioxx or your 8th booster is you believe the Rx companies when they say its safe and effective. They would never hide data or manipulate studies that lead to the death of 60k people. Would they? I mean kill over 60k people and still profit billions.

I do believe that vaccines are safe and effective, and the science is pretty unequivocal there. I've learned that this is an impossible discussion to have, though - I will link the science and statistics, you'll tell me they're fraudulent, I'll ask what data or evidence we're supposed to go by, you'll say some stuff that happened to your friends or family, or that you heard from other people about themselves or their friends and family, I'll say anecdotes are useless, you'll say they aren't because you can't trust the science because apparently big pharma wants to kill their customers for some reason, and around and around we go for pages and pages.

Let's agree to disagree. I'll keep getting vaccines, you do what you want.

The American Heart Association (AHA)
initially opposed a Texas bill that would ban the purchase of junk food with SNAP benefits due to concerns about potential impacts on program participation and population health. The organization stated the bill needed to ensure it did not reduce hunger and that public education was a better approach than nutritional restrictions. This opposition drew criticism due to the AHA's conflict of interest, as it receives funding from the food industry. The AHA has since reversed its stance and now supports removing sugary drinks from SNAP

Junk food is so healthy and we don't want out sugar daddy's losing money! As they say follow the money.

The AHA never argued that junk food is healthy, they argued that SNAP's primary purpose is preventing people from being hungry, not enforcing healthy dietary choices.

> “For a bill like this, we would need to be careful that it does not impact overall participation in the SNAP program and that there be adequate education to the public on healthy habits”

I'm not particularly in favor of this idea either - I don't think junk food is healthy, but effectively banning it based on socioeconomic status isn't something I'm in favor of. If anything, I wish the AHA hadn't reversed course here, or better yet, had just refused to weigh in at all.

 

[hexagonal]

There's always multiple ways to look at data.

Revenue is not the same thing as profit.

Profit margins are very small on generics.

 

[keengkong]

Revenue is not the same thing as profit.

Profit margins are very small on generics.

The profits on statins are also widely distributed, with several types of statins, and several companies for each statin.

 

[trtbuilder]

LDL is the primary driver of cardiovascular disease, treatments that lower is save lives. It's beyond dispute backed by an overwhelming body of evidence.

It's not "blindly" believing anything. Not "Big Pharma", "Big Medicine", or any other grand conspiracy supposedly intent on getting people needlessly hooked on cheap generic meds that cost less than $20 a year.

Ghost - you have a ton of good info everywhere but do you have a summary of your current pharma stack anywhere?

 

[Joseph_88]

I follow

 

[keengkong]

I'm the OP. I stopped taking Lipitor because the heptatologist suggested it might be the cause of my severely elevated liver enzymes. Today I received blood tests showing my liver enzymes are now close to normal levels although my LDL cholesterol is up to 135 (normal is < 100). Since my dad died of a heart attack and age 62 and I (56) have some plaque build-up in a coronary artery, it's important that I reduce risk. The cardiologist first suggested that I take Zetia but then said it wouldn't work nearly as well as Lipitor. I then asked about pitavastatin. She said pitavastatin would work much better and that she'd monitor it to see if it caused liver problems. (Although statins frequently cause liver problems, most people who have had a liver problem with one statin can transition to a different statin. Also, pitavastatin may have a lower risk of causing liver problems than other statins.) I was glad I didn't have to fight to get pitavastatin. She said if there was a problem with pitavastatin, then we'd likely be able to get one of the newer cholesterol lowering medicines approved.

 

[RockyP]

I'm the OP. I stopped taking Lipitor because the heptatologist suggested it might be the cause of my severely elevated liver enzymes. Today I received blood tests showing my liver enzymes are now close to normal levels although my LDL cholesterol is up to 135 (normal is < 100). Since my dad died of a heart attack and age 62 and I (56) have some plaque build-up in a coronary artery, it's important that I reduce risk. The cardiologist first suggested that I take Zetia but then said it wouldn't work nearly as well as Lipitor. I then asked about pitavastatin. She said pitavastatin would work much better and that she'd monitor it to see if it caused liver problems. (Although statins frequently cause liver problems, most people who have had a liver problem with one statin can transition to a different statin. Also, pitavastatin may have a lower risk of causing liver problems than other statins.) I was glad I didn't have to fight to get pitavastatin. She said if there was a problem with pitavastatin, then we'd likely be able to get one of the newer cholesterol lowering medicines approved.

Given your family history and current risk factors I would titrate to 4 mg pita and add 10 mg Zetia. After that maybe even add Bemp acid. Will get your LDL down a good 60% from baseline with minimal side effects.

 

[keengkong]

Those are good ideas. Over the last four years, prior to stopping Lipitor, my LDL was consistently below 100 and sometimes below 70. It seems like I ought to try to get it below 70 consistently. That will probably require 4 mg of pitavastatin and something else. I did see that my pitavastatin was delayed due to an insurance issue. I suspect that it's a request for a prior authorization from the doctor. I imagine the conversation will go something like this: The patient can't take Lipitor due to liver problems. If you don't approve this, I'll have to request one of the expensive, fancy new drugs.

 

[Wizbang]

Those are good ideas. Over the last four years, prior to stopping Lipitor, my LDL was consistently below 100 and sometimes below 70. It seems like I ought to try to get it below 70 consistently. That will probably require 4 mg of pitavastatin and something else. I did see that my pitavastatin was delayed due to an insurance issue. I suspect that it's a request for a prior authorization from the doctor. I imagine the conversation will go something like this: The patient can't take Lipitor due to liver problems. If you don't approve this, I'll have to request one of the expensive, fancy new drugs

I just went through prior auth with my insurance (very good platinum ins) who denied them using pita and stated I would need to show intolerance to EVERY single other statin before they would authorize it. Sooooo I went to Costplus sans insurance for 26 bucks shipped to my house.

 

[RockyP]

Those are good ideas. Over the last four years, prior to stopping Lipitor, my LDL was consistently below 100 and sometimes below 70. It seems like I ought to try to get it below 70 consistently. That will probably require 4 mg of pitavastatin and something else. I did see that my pitavastatin was delayed due to an insurance issue. I suspect that it's a request for a prior authorization from the doctor. I imagine the conversation will go something like this: The patient can't take Lipitor due to liver problems. If you don't approve this, I'll have to request one of the expensive, fancy new drugs.

I paid out of pocket for mine. Didn’t feel like waiting for the PA. CostPlus is the way to go.

 

[thestruggle]

Max dose Rosuvastatin. 40mg, lowers LDL roughly 63% (vs 47% with Pita 4mg). But the Rosu side effect rate more than doubles vs the standard 10mg Rosu dose, and the risk of new onset diabetes increases much more than that.

Pita 4mg, combined with 10mg Ezetimebe (available from India as a single pill combo), lowers LDL by 60%, with the same excellent long term safety profile, and a near zero risk of muscle sides for the vast majority. If you need even more add Bempedoic acid to get 70% LDL reduction and still have a far lower chance of sides.

Finally, adding a PCSK9 inhibitor to all this tops out at 90% LDL reduction, with the cumulative side effect risk of all 4 still lower than that of any other statin taken by itself.

Thank you for sharing you knowledge on the topic. It was really helpful for me.

I'd appreciate your input here, if possible:

Post in thread 'Lipid control on TRT using standardized Bergamot extract?'

Oct 22, 2025

Been talking to my doctor today, and he believed I'm talking non-sense when I talk about longterm apob exposure considering my angio test showed no plaques atm.

He thought I should only take statins or think about lipid control if my arteries show signs of plaque development.

Having read @Ghoul posts around the topic I'm looking to somehow source Pita 4mg, combined with 10mg Ezetimebe as a EU resident.

Do you know vendor names that provide such a mix?

• thestruggle

 

[Avies48]

I just went through prior auth with my insurance (very good platinum ins) who denied them using pita and stated I would need to show intolerance to EVERY single other statin before they would authorize it. Sooooo I went to Costplus sans insurance for 26 bucks shipped to my house.

But even with costplus u still need a doctor script to be sent right? So did that original doc submit the script to costplus?

 

[Wizbang]

But even with costplus u still need a doctor script to be sent right? So did that original doc submit the script to costplus?

After it was sent into my local pharm and they said it was prior auth I had the doc send it to costplus just in case anticipating it would be denied since that is a common outcome with pitavastatin

 

[Joseph_88]

Hi, do you know where I can buy pitavastatin online in Europe?

 

[keengkong]

I’m

Hi, do you know where I can buy pitavastatin online in Europe?

Does PCT 24X7 ship to Europe?