Oxandrolone lowered total testosterone 36% while on TRT?

This is where we differ. He says that the lower shbg does not raise free T. I'm reading the links he has provided and they also are saying lowering shbg does not raise free T. Does proviron raise free T by some other mechanism?
its not that simple and i think you're overcomplicating something simple.

low total test low shbg high free t, you wont


high total test, high shbg, low-normal free t you will in rare cases
 
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Does proviron raise free T by some other mechanism?
The only way another exogenous drug could raise FT while someone is taking exogenous Test (assume HPTA shutdown) is by changing its clearance rate via the liver or distribution volume (can't see it doing the latter). You got it.

Caveat is LH agonist, making the testes work again. HCG, etc, etc. 17-aa AAS aren't that.
 
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This is where we differ. He says that the lower shbg does not raise free T. I'm reading the links he has provided and they also are saying lowering shbg does not raise free T. Does proviron raise free T by some other mechanism?
thats also what im saying.

abusing the dynamic equilibrium with shbg : ft to get temporoary results isnt gonna raise your ft in the long run.


using provirion while you're natty and your shbg is sky high and binding alot of your test up? heck yeah it can raise your ft
 
The only way another exogenous drug could raise FT while someone is taking exogenous Test (assume HPTA shutdown) is by changing its clearance rate via the liver or distribution volume (can't see it doing the latter). You got it.

Caveat is LH agonist, making the testes work again. HCG, etc, etc. 17-aa AAS aren't that.
i was not talking about exogoenous test in this instance, i said in the oxa case its 100% not true but in another case its true.

why would u use proviron while on anything exogenous anyway? it kills your shbg compared to natty
 
i was not talking about exogoenous test in this instance, i said in the oxa case its 100% not true but in another case its true.

why would u use proviron while on anything exogenous anyway? it kills your shbg compared to natty
Thank you for clarifying. The original post dealt with exogenous Test case.

For the Proviron/natty case, you have given me something to think about. In that case FT is being generated by testes. Is your argument that Proviron will increase FT production in the testes (generation term)? That's the only way I could see FT being increased once Priviron is added to a natty and endogenous levels reach new steady state ("stable" state).
 
Thank you for clarifying. The original post dealt with exogenous Test case.

For the Proviron/natty case, you have given me something to think about. In that case FT is being generated by testes. Is your argument that Proviron will increase FT production in the testes (generation term)? That's the only way I could see FT being increased once Priviron is added to a natty and endogenous levels reach new steady state ("stable" state).
both that, liver cleareance. and shbg can generally just get skewed by alot of different factors, such as age, diseases etc making it not match your body.

so some people will naturally end up with too high shbg levels locking up their potential ft levels as naturals. steroids ofc bypass this
 
this time we are on the same page i was firing a joke
Shit, when aren't we? Give me a hug!!

steve grand hug GIF
 
both that, liver cleareance. and shbg can generally just get skewed by alot of different factors, such as age, diseases etc making it not match your body.

so some people will naturally end up with too high shbg levels locking up their potential ft levels as naturals. steroids ofc bypass this
This is really important concept and still active area of research...free hormone hypothesis (i know you know). Just stating it for readers. The role SHBG plays in getting androgens /hormones to the tissue (transport) is still puzzling. So SHBG may not be simply locking up FT.

Wild stuff. Thanks for mentioning.

 
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