Inkniron87
Member
Now we wait for Sunday night
MESO-Rx
Anabolic Steroids
OEP LABS Domestic
- Thread starter OEP LABS
- Start date
PiscesMoon
Member
Awesome news, thank you for stepping up to help with this. Cheers @DoubleDeez for making the request here with @OEP LABS
Infernalmango
Member
Thankful @OEP LABS gave me the opportunity to trial his test d. Arrived today, took a half ml to the delt, and hit shoulders a few hours later. First timer using anything higher concentration than 250mg/ml. Zero hint of pip thus far, but will update again tomorrow night. Thanks again pench.
bigdaddyandfriends
Member
Two groups of people in terms of how they handle E2:
Those with naturally high DHT levels - will typically tolerate E2 over reference range with few or no symptoms. Tendency to be bald or have MPB. Basically DHT (and its 'derivatves') are negative allosteric regulators for the ER, decreasing its activity.
Those with low-normal DHT levels will typically not tolerate e2 over reference range without symptoms, low libido and/or ED among the first to appear primarily; the ED is typically not staying hard enough to finish the act. This is why so many men who go on cookie cutter TRT have these issues after an initial honeymoon period. Also as levels continue to rise expect to see emotional lability, jealousy, water retention and weight gain, high blood pressure, gynecomastia, high blood pressure will start to appear.
Testosterone itself will not affect high estrogen, other than its indirect effect on DHT, so there is no magic testosterone/estrogen ratio.
Ultimately high E2 levels in men regardless of DHT are linked with development of prostate cancer, so definitely best to keep them in or near range whether higher levels are tolerated or not. I feel/function best with E2 @ 25-35; that is enough to do all the good things estrogen does (as someone mentioned, ^HDL, GH>IGF1 conversion, joint lubrication, antioxidant/neuroprotective properties) without causing problems. Most of the benefits of estrogen in men are mediated via ERb not ERa, so keeping E2 low and supplementing with soy isoflavones ie genistein is an option if you want to really maximize IGF-1 conversion. Although they have a bad rep as 'endocrine disruptors' they in fact are agonists 90% selective to ERb.
Obviously the only way to directly reduce E2 levels is to reduce aromatizing compounds (ie test, also trestolone and dbol) or use an AI. And not everyone responds well to AIs, they are dosed for complete estrogen elimination in women with breast cancer, not for men who want to knock their E2 conversion down by 10-20%. IMO aromasin is easily the best option, if you can get the dosing right. it has no unwanted effects and while a pain the 25mg tablets can be split into 6.25mg quarters... one or two of those pieces per week might be enough for many people.
Those with naturally high DHT levels - will typically tolerate E2 over reference range with few or no symptoms. Tendency to be bald or have MPB. Basically DHT (and its 'derivatves') are negative allosteric regulators for the ER, decreasing its activity.
Those with low-normal DHT levels will typically not tolerate e2 over reference range without symptoms, low libido and/or ED among the first to appear primarily; the ED is typically not staying hard enough to finish the act. This is why so many men who go on cookie cutter TRT have these issues after an initial honeymoon period. Also as levels continue to rise expect to see emotional lability, jealousy, water retention and weight gain, high blood pressure, gynecomastia, high blood pressure will start to appear.
Testosterone itself will not affect high estrogen, other than its indirect effect on DHT, so there is no magic testosterone/estrogen ratio.
Ultimately high E2 levels in men regardless of DHT are linked with development of prostate cancer, so definitely best to keep them in or near range whether higher levels are tolerated or not. I feel/function best with E2 @ 25-35; that is enough to do all the good things estrogen does (as someone mentioned, ^HDL, GH>IGF1 conversion, joint lubrication, antioxidant/neuroprotective properties) without causing problems. Most of the benefits of estrogen in men are mediated via ERb not ERa, so keeping E2 low and supplementing with soy isoflavones ie genistein is an option if you want to really maximize IGF-1 conversion. Although they have a bad rep as 'endocrine disruptors' they in fact are agonists 90% selective to ERb.
Obviously the only way to directly reduce E2 levels is to reduce aromatizing compounds (ie test, also trestolone and dbol) or use an AI. And not everyone responds well to AIs, they are dosed for complete estrogen elimination in women with breast cancer, not for men who want to knock their E2 conversion down by 10-20%. IMO aromasin is easily the best option, if you can get the dosing right. it has no unwanted effects and while a pain the 25mg tablets can be split into 6.25mg quarters... one or two of those pieces per week might be enough for many people.
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DieselSemi
New Member
I haven't tested my DHT, but I rarely get high E2 sides. Maybe a bit of spicy nips and slight water retention in my legs. But low E2 fucks me up, I flatten out loose my strength, get depressed, tired, and sleep goes to shit even at an E2 of 14. I am also a low aromatizer, even 100 mg of EQ with 400 test had my E2 low. Oh i also am 32 and have 90 percent of my hair and don't feel that I have the typical high DHT sides. Not a ton of body hair or a super thick beard. I really should check my DHT out of curiosity now.
Oldhand
Member
Dial It In
Member
Screw it it’s just hair I’ll take the trade off. Got a way younger one and she don’t care lol
Dial It In
Member
Dial It In
Member
Hmmmm…… wonder who that was? Bet it’s dosed right from here.Good morning! Myself and other ladies on HRT are in need of a solid domestic source who carries estradiol (Cyp preferred for me personally). I inquired about it elsewhere and the vendor replied with a gif that didn’t answer my question and then someone else sent me here so… I was curious if you’d be willing to brew this? I know a handful of people here who would buy it for themselves or their wives. It’s the hormone that makes us ladies eager little people-pleasers, every source should be offering this in my humble opinion. Not to mention HRT clinics are so ridiculously overpriced.
Thank you for your consideration.
Dial It In
Member
Unusual question but as a lady perhaps you can have a take or knowledge. Do you know if this protocol has any impact on improving endometriosis symptoms?Good morning! Myself and other ladies on HRT are in need of a solid domestic source who carries estradiol (Cyp preferred for me personally). I inquired about it elsewhere and the vendor replied with a gif that didn’t answer my question and then someone else sent me here so… I was curious if you’d be willing to brew this? I know a handful of people here who would buy it for themselves or their wives. It’s the hormone that makes us ladies eager little people-pleasers, every source should be offering this in my humble opinion. Not to mention HRT clinics are so ridiculously overpriced.
Thank you for your consideration.
DoubleDeez
Banned for using multiple active alt accounts
Yeaaaaah my Lady Test from that other vendor sketches me out lol and I won’t be using that til I can send my own vial off to be tested. Not to mention, that vial has the shitty clear stopper.
I have been hearing great things about OEP and my expectations are high. I know if Photon recommends them, they’ve gotta be good; the man has high standards.
DoubleDeez
Banned for using multiple active alt accounts
It absolutely can! HRT can alleviate pain and pelvic cramping associated with endo, prevents bone loss which is a concern for those who undergo early menopause due to surgical interventions, it really just improves quality of life overall.
Found this, because I’m unsure of the person’s specific situation:
AllGoodThings
Member
I have a bunch of vials from the same source that I bought for my wife, and the fact that one independent Jano test showed 63mg/ml, while the vendor's Jano test came back at 55mg/ml for what was supposedly the same batch, did not inspire a ton of confidence in the product.Yeaaaaah my Lady Test from that other vendor sketches me out lol and I won’t be using that til I can send my own vial off to be tested. Not to mention, that vial has the shitty clear stopper.
I have been hearing great things about OEP and my expectations are high. I know if Photon recommends them, they’ve gotta be good; the man has high standards.
OEP is my favorite source here, and he has great attention to detail, so I'm sure anything he makes for women will have accurate dosing.
Dial It In
Member
Oh these stoppers are game changing. Month in and can’t see it’s been punched.Yeaaaaah my Lady Test from that other vendor sketches me out lol and I won’t be using that til I can send my own vial off to be tested. Not to mention, that vial has the shitty clear stopper.
I have been hearing great things about OEP and my expectations are high. I know if Photon recommends them, they’ve gotta be good; the man has high standards.
DoubleDeez
Banned for using multiple active alt accounts
I would disregard the “still menstruating” bit at the end. Lots still believe estrogen isn’t necessary or beneficial to those who are still menstruating, but I am living proof that it is.
Dial It In
Member
The condition is responds to progesterone better than estrogen. Has the IUD that is slow release progesterone and no hysterectomy.
Coffezilla
Member
sent you a dmYeaaaaah my Lady Test from that other vendor sketches me out lol and I won’t be using that til I can send my own vial off to be tested. Not to mention, that vial has the shitty clear stopper.
I have been hearing great things about OEP and my expectations are high. I know if Photon recommends them, they’ve gotta be good; the man has high standards.
DoubleDeez
Banned for using multiple active alt accounts
It’s not really my area of expertise so I will refrain from offering any real advice here. I know estrogen has done wonders for me personally and I consider it a miracle drug, and I don’t respond very well to progesterone but I have to take it for half the month. I wish you and the lady luck, and hope she can find some solid relief.
Dial It In
Member
I understand. But I really appreciate your take on this. It has been helpful and opened a good discussion with the other half. Let’s call it Sister Science. It’s a good start to open up with a endo doc for sure.
Dial It In
Member
Yeah definitely questionable on that one. No doubt this will be done correct.
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