Photon
Member
Anyone running a Trest only cycle soon with zero Test? Could you pull DHT labs to see pre and mid cycle DHT? Without any Test, is there a need to supplement exogenous DHT?
@bigdaddyandfriends
@bigdaddyandfriends
MESO-Rx
Anabolic Steroids
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sionnach
Banned
Seconded, would love to see full before/during/after labs if anyone does this. Hematocrit/rbc, estradiol, SHBG, DHT, progesterone, prolactin, IGF (if not on GH), etc and logs of BP/rhr.
Photon
Member
Very interesting read here on dht derivatives.
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Still only 13 cents per unit.
View: https://www.youtube.com/watch?v=7NyVKMOSuOM
2 min in. Lmao.
OEP LABS
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Received an email from Jano team dated
Sept 15, 2025 they received the samples. They don’t take long to get results. As soon as I hear anything I’ll post the reports.
T&H
Member
As others stated, nothing but excellent communication, shipping, and overall experience. Used OEP in the past and this is how he's always rolled. Looking forward to the coming Test C/E results.
Nice thanks.
OEP LABS
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Thank you sir !
Appreciate you T&H!
Got you. Most definitely will notify you
Will be starting you TP next week...will pull labs in 6 weeks or so and let ya know how they look.
OEP LABS
Subscriber
Please keep me informed will give you credit as well.
bigdaddyandfriends
Member
You can use HCG (~ 333iu three times a week) and/or very low test ~ 50-70mg to maintain adequate DHT levels. Trestolone is potent enough to replace DHT as an androgen for libido (several human trials were done) but that will not account for loss of the 3⍺-diol (active on GABA-A) and 3β-diol (active on ERβ) neurosteroid metabolites in the brain.
I've run trestolone with and without low dose test & HCG, I do feel better with it. Estrogen control only becomes an issue with typical "test base doses" ie 200+ mg/wk, and anastrozole is not very effective in combating that.
I'm planning a long term cruise after this month with trestolone, low dose HCG + test & mast (for SHBG-RSHBG), and EQ. Already started on the EQ as it takes so long to build up.
Photon
Member
Are you relying on hcg for dht and e2?
It's strange how it almost seems like we're going out of our way to avoid test, given it's probably the most natural compound there is lol....
Last edited:
bigdaddyandfriends
Member
You don’t need e2. The 7α-methylestrogen replaces it. In the pellet studies reporting loss of bone density, the trestolone dose < 1600 mcg/day was insufficient for estrogen. Had the gone up to 2400-2800mcg, bone density would have been maintained That’s the true trestolone replacement dose; problem is that is like a mini-blast of androgens and the study endpoint was carefully selected to avoid physique enhancement.
Basically
TestRT = physiologic androgen @ estrogen
TrestRT = supraphysiologic androgen & physiologic estrogen, or physiologic androgen & sub-physiologic estrogen
With test + HCG, there will be a mix of e2 & 7α-me-e2. Combined you want them upper range of physiologic, which means e2 should be mid-low range, as the estrogen from trestolone is not detected on blood work.
At a few mg per day it’s not generally a big deal, but if trying to push the trestolone dose with Aromasin, it is really important to know how your body feels relative to high and low estrogen levels.
Photon
Member
Is this with the assumption that EQ has minimal effect on 7a methyl e2?
bigdaddyandfriends
Member
if EQ (or a metabolite) is a non-competitive AI it will work with trestolone, it aromatizes exactly the same as testosterone just with lower efficiency but into a more potent (synthetic) estrogen. If competitive it will work but with reduced efficiency at typical dosages.
The anabolic:androgenic ratio is borderline worthless for various reasons (a major one being use of the levator ani muscle rather than a muscle that actually can be overloaded/stressed). But if one were to have an anabolic:androgenic:estrogenic ratio with test being 100:100:100, trestolone would be about 2300:650:200. High doses sound perfect here… but anabolism maxes out at a fairly low dosage, beyond which you just accumulate more androgenicity/estrogenicity. This is true with basically all high potency androgens. Thst’s why no one can use metribolone or mibolerone to grow - the anabolism gives way to side effects at exceeding low (mcg) dosages. And this is why using MENT at > 25-35/mg per usually ends in failure. For most 5-10mg/day is the ‘sweet spot’, elite bodybuilders with very high muscle mass being an exception. For replacement therapy (which few here are really interested in) 2-3mg/day is plenty!
Interestingly trestolone’s sister compound Trenbolone is always specified as 500:500. But - that is referenced not to testosterone, but to nandrolone in Llewelyn’s book. So trenbolone is similar to nandrolone at 5x potency… referenced back to testosterone, nandrolone @ 125:37 x5 = 625:185, which I and I think most trenbolone users would likely agree with. Not that I would recommend it, but either could be used to better effect by women bodybuilders compared to testosterone. I personally like 5mg ea per day on a cruise.
So yes testosterone is natural and good/healthy at HRT levels, particularly when we’re young and our bodies can ideally balance androgens/estrogens. Problem is taking larger amounts to build or maintain lean body mass results in excessive estrogen and/or DHT; or as we age, estrogen/androgen ratio becomes dysregulated. Test is the only compound that creates DHT, which is unique; the so-called DHT derivatives are all completely different in how they act in the body - basically as a non-aromatizing, typically weakened androgen that cannot be converted in a tissue specific manner to either a useless androgen (skeletal muscle) or highly potentiated androgen (prostate and skin appendages ie hair follicles and sebaceous glands).
Too much estrogen and DHT is a recipe for prostate cancer, they act in synergy in conjunction with SHBG-RSHBG, which is why I prefer keep my test levels low being older… a major part of my day job is reading mpMRI and PSMA PET scans, and I see our natural hormones play a major role in development of cancer as we age and estrogen levels rise. Most new diagnosis patients have gyno and estrogenic body habitus; I’ve yet to see a case in a younger muscular man with naturally high androgen and lower estrogen levels - natural or not.
The anabolic:androgenic ratio is borderline worthless for various reasons (a major one being use of the levator ani muscle rather than a muscle that actually can be overloaded/stressed). But if one were to have an anabolic:androgenic:estrogenic ratio with test being 100:100:100, trestolone would be about 2300:650:200. High doses sound perfect here… but anabolism maxes out at a fairly low dosage, beyond which you just accumulate more androgenicity/estrogenicity. This is true with basically all high potency androgens. Thst’s why no one can use metribolone or mibolerone to grow - the anabolism gives way to side effects at exceeding low (mcg) dosages. And this is why using MENT at > 25-35/mg per usually ends in failure. For most 5-10mg/day is the ‘sweet spot’, elite bodybuilders with very high muscle mass being an exception. For replacement therapy (which few here are really interested in) 2-3mg/day is plenty!
Interestingly trestolone’s sister compound Trenbolone is always specified as 500:500. But - that is referenced not to testosterone, but to nandrolone in Llewelyn’s book. So trenbolone is similar to nandrolone at 5x potency… referenced back to testosterone, nandrolone @ 125:37 x5 = 625:185, which I and I think most trenbolone users would likely agree with. Not that I would recommend it, but either could be used to better effect by women bodybuilders compared to testosterone. I personally like 5mg ea per day on a cruise.
So yes testosterone is natural and good/healthy at HRT levels, particularly when we’re young and our bodies can ideally balance androgens/estrogens. Problem is taking larger amounts to build or maintain lean body mass results in excessive estrogen and/or DHT; or as we age, estrogen/androgen ratio becomes dysregulated. Test is the only compound that creates DHT, which is unique; the so-called DHT derivatives are all completely different in how they act in the body - basically as a non-aromatizing, typically weakened androgen that cannot be converted in a tissue specific manner to either a useless androgen (skeletal muscle) or highly potentiated androgen (prostate and skin appendages ie hair follicles and sebaceous glands).
Too much estrogen and DHT is a recipe for prostate cancer, they act in synergy in conjunction with SHBG-RSHBG, which is why I prefer keep my test levels low being older… a major part of my day job is reading mpMRI and PSMA PET scans, and I see our natural hormones play a major role in development of cancer as we age and estrogen levels rise. Most new diagnosis patients have gyno and estrogenic body habitus; I’ve yet to see a case in a younger muscular man with naturally high androgen and lower estrogen levels - natural or not.
OEP LABS
Subscriber
@newguy2 as promised notifying you sir
EQ raw is from China.
Test Enanthate raw from China
Test Cyp batch A6 India
Tren E raw from India
HPLC raw reports below. I did 6-7% overdose tolerance for EQ as history has it, can test low for in regards to purity. The remaining hormones did a 3-4% tolerance OD for target.
Several factors can affect purity from my experience, such as shelf life, Sunlight, location of storage, can decrease the potency of the hormone. Each one can be corrected by either adding more material or reducing the carrier by tolerance of 8~9%.
The GCMS and HPLC report for Test Cyp is still pending, no rush on the Jano team. Glad they can provide us with reports and fast service. Reports attached.
We will be testing everything for Target HPLC. In my opinion I’m confident I can nail it or slightly be
Under 3-4%. Please your input is appreciate how I should proceed
EQ raw is from China.
Test Enanthate raw from China
Test Cyp batch A6 India
Tren E raw from India
HPLC raw reports below. I did 6-7% overdose tolerance for EQ as history has it, can test low for in regards to purity. The remaining hormones did a 3-4% tolerance OD for target.
Several factors can affect purity from my experience, such as shelf life, Sunlight, location of storage, can decrease the potency of the hormone. Each one can be corrected by either adding more material or reducing the carrier by tolerance of 8~9%.
The GCMS and HPLC report for Test Cyp is still pending, no rush on the Jano team. Glad they can provide us with reports and fast service. Reports attached.
We will be testing everything for Target HPLC. In my opinion I’m confident I can nail it or slightly be
Under 3-4%. Please your input is appreciate how I should proceed
Attachments
Photon
Member
Total purity is pretty good, 99%.
But it feels dishonest, i think they swapped it out knowingly, to a raw that doesn't have high demand for, is much cheaper and needs much more solvents to use (TNE). On the plus side..at least they used TNE and not roadside dust.
sionnach
Banned
I'd seek some sort of compensation from the vendor, but I'd also brew/buy/pin the fuck out of that. The long/short of cyp/NE is a strange combo, so it'd have to be a daily for me, but fuck it, at least it's 99%. Mix it up as a limited batch, @OEP LABS , just make sure the customer knows what it is.
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