OEP LABS Domestic

For AI only use Aromasin. It is a non-competitive AI and permanently disables the aromatase enzyme, reducing the overall amount of conversion taking place. Basically, if one is a high aromatizer - like someone that needs AI on TRT dose test, Aromasin will turn you into a lower aromatizer, without any other effects.

Arimidex is a competitive inhibitor, meaning it will compete with aromatizing androgens to bind with aromatase. That works okay with something that binds to aromatase with high affinity like testosterone or androstenedione, but not so much with a compound that binds with much less efficiency (trestolone, nandrolone, boldenone and dianabol).

If you know how much Aromasin is needed for a certain test dose, use the sum of test mg + (trestolone mg x 2) to approximate an equivalently estrogenic dose of testosterone only.

I’ve read on places like Reddit and Evolutionary that trestolone doesn’t aromatize but gets ‘metabolized to methyl estrogen’ in the liver, and AIs therefore do not work. That is factuallly false, it aromatizes just like other compounds but to 7α-methylestradiol. It has similar binding efficiency to ERα and ERβ as estradiol 102%) but in vitro study showed 4x transactivation of ERα in a hormone resistant breast cancer cell line, compared to estradiol.

After a couple hours, 23% of trestolone aromatizes into 7α-methylestradilol, compared to 13% of nandrolone. As nandrolone supposedly aromatizes at 20% the rate of testosterone, one can interpolate the approximate aromatization from trestolone as (23/13) / 0.2 = 35.4%, compared to testosterone.

So 0.354 aromatization rate x 102% binding affinity x 400% ER trans activation = 1.44x estrogenicity of testosterone per mg. Note: These values come from the article here by Type-IIx; I have confirmed them.

I personally round the estrogenicity up to 2x, however, because the 7α-methylation blocks both trestolone and its methylestrogen from SHBG binding, so the sex hormones are 100% free. This potentiates the potency of both, which is good and more significant for the androgen, but not so much for the estrogen. Estrogen does bind to SHBG although to a lesser extent than testosterone, and particularly DHT.

The androgen TRT replacement dose of trestolone is about 1mg/day ~ 100mg test C. In studies with implantable pellets, 409-700mcg was able to maintain or surpass lean body weight, composition, and sexual function as compared to testosterone. However there was loss of bone mass, so the estrogen produced was insufficient/sub-phsiologic. So the estrogen TRT replacement dose of MENT is probably 2-3mg/day… so compared to test your getting about 3x the anabolism for the correct amount of estrogen.

What this means is even with low doses of MENT (say 3mg/day) and test (say 100mg/wk) one is probably doubling the estrogen they need. So use an AI if there are signs of excess estrogen - sudden weight gain = water retention, nipple sensitivity, ED, excessive emotionality, etc.

Crashing your estrogen with trestolone is rare. If you have symptoms related to estrogen with this compound, it’s going to be from high estrogen unless you’re way overdosing AIs. Only if there is extreme fatigue, weakness, dry/creaky/painful joints, and completely absent libido would I consider low estrogen. If you think that’s the case, try high doseDHEA to see if there is short term relief before doing something drastic to spike E2.

Last, there is no such thing as insufficient estradiol with excess methylestradiol causing both low and high E2 symptoms. They sum together and do not act separately in any way.
 
Put me back on ignore bud

For AI only use Aromasin. It is a non-competitive AI and permanently disables the aromatase enzyme, reducing the overall amount of conversion taking place. Basically, if one is a high aromatizer - like someone that needs AI on TRT dose test, Aromasin will turn you into a lower aromatizer, without any other effects.

Arimidex is a competitive inhibitor, meaning it will compete with aromatizing androgens to bind with aromatase. That works okay with something that binds to aromatase with high affinity like testosterone or androstenedione, but not so much with a compound that binds with much less efficiency (trestolone, nandrolone, boldenone and dianabol).

If you know how much Aromasin is needed for a certain test dose, use the sum of test mg + (trestolone mg x 2) to approximate an equivalently estrogenic dose of testosterone only.

I’ve read on places like Reddit and Evolutionary that trestolone doesn’t aromatize but gets ‘metabolized to methyl estrogen’ in the liver, and AIs therefore do not work. That is factuallly false, it aromatizes just like other compounds but to 7α-methylestradiol. It has similar binding efficiency to ERα and ERβ as estradiol 102%) but in vitro study showed 4x transactivation of ERα in a hormone resistant breast cancer cell line, compared to estradiol.

After a couple hours, 23% of trestolone aromatizes into 7α-methylestradilol, compared to 13% of nandrolone. As nandrolone supposedly aromatizes at 20% the rate of testosterone, one can interpolate the approximate aromatization from trestolone as (23/13) / 0.2 = 35.4%, compared to testosterone.

So 0.354 aromatization rate x 102% binding affinity x 400% ER trans activation = 1.44x estrogenicity of testosterone per mg. Note: These values come from the article here by Type-IIx; I have confirmed them.

I personally round the estrogenicity up to 2x, however, because the 7α-methylation blocks both trestolone and its methylestrogen from SHBG binding, so the sex hormones are 100% free. This potentiates the potency of both, which is good and more significant for the androgen, but not so much for the estrogen. Estrogen does bind to SHBG although to a lesser extent than testosterone, and particularly DHT.

The androgen TRT replacement dose of trestolone is about 1mg/day ~ 100mg test C. In studies with implantable pellets, 409-700mcg was able to maintain or surpass lean body weight, composition, and sexual function as compared to testosterone. However there was loss of bone mass, so the estrogen produced was insufficient/sub-phsiologic. So the estrogen TRT replacement dose of MENT is probably 2-3mg/day… so compared to test your getting about 3x the anabolism for the correct amount of estrogen.

What this means is even with low doses of MENT (say 3mg/day) and test (say 100mg/wk) one is probably doubling the estrogen they need. So use an AI if there are signs of excess estrogen - sudden weight gain = water retention, nipple sensitivity, ED, excessive emotionality, etc.

Crashing your estrogen with trestolone is rare. If you have symptoms related to estrogen with this compound, it’s going to be from high estrogen unless you’re way overdosing AIs. Only if there is extreme fatigue, weakness, dry/creaky/painful joints, and completely absent libido would I consider low estrogen. If you think that’s the case, try high doseDHEA to see if there is short term relief before doing something drastic to spike E2.

Last, there is no such thing as insufficient estradiol with excess methylestradiol causing both low and high E2 symptoms. They sum together and do not act separately in any way.
I appreciate you taking the time to write this out, very helpful information, thank you.
 
Some of the last invoices are runnin maybe 1-2 day delay but the anabolic pigeon will get it to you. Please if you have concern contact me

I’m back open again. I have added additional item to list. Yesterday I tried the TU myself, honestly this will be my next goto. It will replace my faithful TestCyp

Test Undecanoate in castor carrier dosed at 320mg/ml. Im sensitive to pip and can say I am impressed. My protocol, was considering 1ML every 10-12 days? What is your protocol would like to hear other opinions.

By the way this material TU will be added to the additional 4 samples already paid for. Requested to add the TU material. They will leave this week. Here is the most updated list with additional item added.


View: https://pastebin.com/ycADzWRT
 
Some of the last invoices are runnin maybe 1-2 day delay but the anabolic pigeon will get it to you. Please if you have concern contact me

I’m back open again. I have added additional item to list. Yesterday I tried the TU myself, honestly this will be my next goto. It will replace my faithful TestCyp

Test Undecanoate in castor carrier dosed at 320mg/ml. Im sensitive to pip and can say I am impressed. My protocol, was considering 1ML every 10-12 days? What is your protocol would like to hear other opinions.

By the way this material TU will be added to the additional 4 samples already paid for. Requested to add the TU material. They will leave this week. Here is the most updated list with additional item added.


View: https://pastebin.com/ycADzWRT

Did my first pin of your 250 today in a 28g and it went right in. No PIP
 
Some of the last invoices are runnin maybe 1-2 day delay but the anabolic pigeon will get it to you. Please if you have concern contact me

I’m back open again. I have added additional item to list. Yesterday I tried the TU myself, honestly this will be my next goto. It will replace my faithful TestCyp

Test Undecanoate in castor carrier dosed at 320mg/ml. Im sensitive to pip and can say I am impressed. My protocol, was considering 1ML every 10-12 days? What is your protocol would like to hear other opinions.

By the way this material TU will be added to the additional 4 samples already paid for. Requested to add the TU material. They will leave this week. Here is the most updated list with additional item added.


View: https://pastebin.com/ycADzWRT


For cruise/trt I think 1ml every 10-12 would be very good, might even be able to do something like 1.25ml and stretch it to every 2 weeks for some people. One way I might use it is as a supplemental background test during blasts to offset some of the oil volume of my shots. A lot of times when I'm doing every other day injections of multiple compounds, I'm maxing out my 3ml syringes, and typically 1cc or more of that is test of some kind. If I did a 2ml shot of your Test U every 10 days, I could drop the other test ester(s) down significantly, and leave room for the other stuff I'm taking. It's has the potential to be a versatile product, and allows for some non-traditional administrative protocols. I'll be sending an email here shortly to order some.
 
Last edited:
From your pastebin:

Part of the price increase is we intend to check all raw purity and forgo hplc testing as well.

You plan on raws testing plus HPLC on finished oils?

If so you may want to edit the word forgo.

 
Test Undecanoate in castor carrier dosed at 320mg/ml. Im sensitive to pip and can say I am impressed. My protocol, was considering 1ML every 10-12 days? What is your protocol would like to hear other opinions.

Castor TU is very rare for US Dom.

I think only 1 other vendor has it and he doesn't test for shit.
I had a hard time finding it last year, gave up and just bought MCT TU.

TU takes a LONG time to get stable levels.
It's best to frontload or take together with your usual Test, till TU is stable.

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