OldGHGuy
Member
GH is like BBQ - best to go low and slow. 2iu per day for 6 months then evaluate progress and re-assess.
MESO-Rx
Anabolic Steroids
new to HGH/Igf-1 dose Advice Needed
- Thread starter Amgiji
- Start date
thank you for the reply.
I know that's the dose for muscle growth when you have years.
in my case I am trying to get taller and that might be a higher does(the only other person to reply had 40iu per 100kg)
and I have only about 9 months (till June 2024) to get results
as I am borderline having osteopenia from taking enough arimidex to keep my growth plates open.
and I will need to cut the dose around then and that will 100% for sure finish off my growth.
do these factors affect your recommendation?
I know that's the dose for muscle growth when you have years.
in my case I am trying to get taller and that might be a higher does(the only other person to reply had 40iu per 100kg)
and I have only about 9 months (till June 2024) to get results
as I am borderline having osteopenia from taking enough arimidex to keep my growth plates open.
and I will need to cut the dose around then and that will 100% for sure finish off my growth.
do these factors affect your recommendation?
OldGHGuy
Member
I am no doctor my friend. I do know 40iu/day will give you extreme side effects. My first recommendation is to read, read and read some more. There are many studies out there that relate to your issue.
The largest study I found used .4 mg/kg/week as a top dose for your purpose. This would equate to:
.4 mg/kg/week
Weight 114kg
46 mg per week
1 mg = 2.7 iu
Need 124 iu per week
Divided by 7 = 18 iu per day
This is still a very large anount of GH so I am not recoemmending it, just showing tou what I found.
The largest study I found used .4 mg/kg/week as a top dose for your purpose. This would equate to:
.4 mg/kg/week
Weight 114kg
46 mg per week
1 mg = 2.7 iu
Need 124 iu per week
Divided by 7 = 18 iu per day
This is still a very large anount of GH so I am not recoemmending it, just showing tou what I found.
OldGHGuy
Member
Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit
Children with Idiopathic Short Stature do not attain a normal adult height. The improvement of adult height with treatment with recombinant human growth hormone (rhGH), at doses of 0.16 to 0.28 mg/kg/week is modest, usually less that 4 cm, ...
www.ncbi.nlm.nih.gov
thank you for showing me what you found.
I've read a few things like that, and I was seeing if people who have experience using gh have any different opinions.
from what I've read the higher the does the better outcome is (to a point)
I'm trying to find what the highest well tolerated doses (which will be individualized) are and to stay away from any truly suicidal amounts.
also, do you happen to know anything about igf-1?
as from what I've read using that in conjunction with GH typically produces better out comes than using GH alone.
I've read a few things like that, and I was seeing if people who have experience using gh have any different opinions.
from what I've read the higher the does the better outcome is (to a point)
I'm trying to find what the highest well tolerated doses (which will be individualized) are and to stay away from any truly suicidal amounts.
also, do you happen to know anything about igf-1?
as from what I've read using that in conjunction with GH typically produces better out comes than using GH alone.
OldGHGuy
Member
No experience with IGF-1. Remember too you are on a Steroid forum where GH is used for bodybuilding/body comp purposes - not height. Maybe there are other forums specific to your purpose.
At the end of the day, theres no free lunch. More iu = more side effects. And everyone is different so you have to find out YOUR tolerance.
At the end of the day, theres no free lunch. More iu = more side effects. And everyone is different so you have to find out YOUR tolerance.
"everyone is different so you have to find out YOUR tolerance" I know I said the highest well tolerated doses will be individualized.
there are other forms.
but when you get a stack from them it's insane here's one, I found for example.
1 25mg of mk677 morning and 25mg mk677 night. Every day.
2 5000mcg CJC-1295 DAC subQ inject before bed – Monday, Wednesday, Saturday
3Hexarelin 100mcg 3x-4x daily for 2 weeks then GHRP-2 100mcg 3x-4x daily for 4 weeks then repeat back to hexarelin and so on
4 CJC no DAC 100mcg 3x-4x daily with hexarelin or GHRP2 from number 1.Inject on an empty stomach (waking up or 3 hours after eating) and eat after 30 minutes.
5 IGF-1 DES injected at the the deltoids (shoulder muscles) 40mcg each side
6 Flubiprofen 200-300 mg/day divided through 6-12 hours (eg. take 150 morning and 150 night
7 Aromasin: choose from 12.5mg one day on one day off till 25mg everyday. (your choice)
OR
Arimidex 1mg per day.
OR
Letrozole: choose from 0.5 mg one day on one day off till 2.5mg daily
8 DHT gel on penis twice daily or 11-KDHT one drop on each forearm daily
9 SAM-e 1500mg every day
10 MSM 1000mg every day
11 Glucosamine 1500mg every day
12 Chondroitin 1200mg every day
13 Building blocks
Vitamin D 10k IU per day
Vitamin k2 mk4 45mg per day
Magnesium 400mg per day
Zinc 50mg per day
Calcium 2g per day
Boron 9mg per day
what I'm looking for is something like this with the dose amounts, what to use together, when to cycle and what to cycle to, even if fasting and time of day,
(that why I put the same question about DHT in the anabolic steroids sub form)
but dosed for people who want to get taller and masculinize and
not for finding the most convoluted way to overdose.
there are other forms.
but when you get a stack from them it's insane here's one, I found for example.
1 25mg of mk677 morning and 25mg mk677 night. Every day.
2 5000mcg CJC-1295 DAC subQ inject before bed – Monday, Wednesday, Saturday
3Hexarelin 100mcg 3x-4x daily for 2 weeks then GHRP-2 100mcg 3x-4x daily for 4 weeks then repeat back to hexarelin and so on
4 CJC no DAC 100mcg 3x-4x daily with hexarelin or GHRP2 from number 1.Inject on an empty stomach (waking up or 3 hours after eating) and eat after 30 minutes.
5 IGF-1 DES injected at the the deltoids (shoulder muscles) 40mcg each side
6 Flubiprofen 200-300 mg/day divided through 6-12 hours (eg. take 150 morning and 150 night
7 Aromasin: choose from 12.5mg one day on one day off till 25mg everyday. (your choice)
OR
Arimidex 1mg per day.
OR
Letrozole: choose from 0.5 mg one day on one day off till 2.5mg daily
8 DHT gel on penis twice daily or 11-KDHT one drop on each forearm daily
9 SAM-e 1500mg every day
10 MSM 1000mg every day
11 Glucosamine 1500mg every day
12 Chondroitin 1200mg every day
13 Building blocks
Vitamin D 10k IU per day
Vitamin k2 mk4 45mg per day
Magnesium 400mg per day
Zinc 50mg per day
Calcium 2g per day
Boron 9mg per day
what I'm looking for is something like this with the dose amounts, what to use together, when to cycle and what to cycle to, even if fasting and time of day,
(that why I put the same question about DHT in the anabolic steroids sub form)
but dosed for people who want to get taller and masculinize and
not for finding the most convoluted way to overdose.
OldGHGuy
Member
I dont think it exists
yes I know it doesn't exist, the point was to try and make one. people can ask similar questions and get this level of detail as an answer
""LR3 IGF-I is not well understood. Various considerations apply to its practical use for muscle growth. These include the fact that its resistance to binding IGFBP-3 renders it less potent vs. IGF-1 (rhIGF-I; mecasermin; Increlex) per-mcg when used systemically & by extension, less potent vs. GH (rhGH) under the same conditions (rhGH > rhIGF-I > LR3 IGF-I in potency to increase total body & muscle size [mitogenic & myogenic effects]).
For example, where a 2 IU/m² (BSA) rhGH dose, or 3.8 IU/d for a 75 kg, 5'9" (175.25 cm) man, serum IGF-I ↑ from 162→439 μg/L (high-normal). An 80 μg/kg (6 mg/d for that same average build man) serum IGF-I ↑ 156→342 μg/L. LR3, then, used systemically by a bodybuilder (characterized by high body surface areas & body weights) probably requires doses above 6 mg/d for equivalent potency to rhIGF-I – however, note that LR3 IGF-I will more likely reduce serum IGF-I because it is an IGF-I analogue designed specifically for rapid clearance & resistance to IGFBP binding.
If you are wondering how rhGH can be superior to rhIGF-I in increasing IGF-I, it is because GH in healthy individuals potently stimulates its synthesis & secretion. RhIGF-I is approved for one rare condition: Severe Primary IGF-I Deficiency (Primary IGFD). Having this condition means that your liver is resistant to GH stimulation of IGF-I. It is, then, a workaround option, to directly administer IGF-I despite its inferiority if otherwise non-primary-IGFD. Its financial expense arises because of market forces, supply & demand, and probably R&D, manufacturing, and transport/supply chain factors.
If LR3 IGF-I is to be used, it should be while bulking (energy in > out) on a per-muscle (not muscle group) rotational basis since it is less potent systemically (due to resistance to IGFBP-3 binding) than rhIGF-I & rhGH.
Split dosing (e.g., 2X/d > 1X/d; b.i.d.; b.d.s.) is superior to once-daily dosing (q.d.) because of the rapid clearance and low biological half-life of LR3 IGF-I that is particularly resistant to IGFBP binding.
LR3 IGF-I is more potent than any other known agent in its propensity to increase gut/visceral organ growth.
LR3 IGF-I's use is limited to a very particular use case – to increase the pool of available myofibers for subsequent hypertrophy in those very muscular bodybuilders that have already reached the limit of their pool (mitogenic vs. myogenic effects). Its propensity to induce hypoglycemia attaches with similar considerations to insulin (rhI) use.
The financial expense and relatively weak potency of LR3 to directly stimulate muscle growth (and very poor performance in anticatabolism, to stave off muscle losses during dieting) limit its versatility tremendously and make it an unlikely choice for the average reader. This one is really for the very advanced bodybuilder.""
since there are people who clearly know what they are talking about.
anyone want to take a shot at dosing levels/methods?
""LR3 IGF-I is not well understood. Various considerations apply to its practical use for muscle growth. These include the fact that its resistance to binding IGFBP-3 renders it less potent vs. IGF-1 (rhIGF-I; mecasermin; Increlex) per-mcg when used systemically & by extension, less potent vs. GH (rhGH) under the same conditions (rhGH > rhIGF-I > LR3 IGF-I in potency to increase total body & muscle size [mitogenic & myogenic effects]).
For example, where a 2 IU/m² (BSA) rhGH dose, or 3.8 IU/d for a 75 kg, 5'9" (175.25 cm) man, serum IGF-I ↑ from 162→439 μg/L (high-normal). An 80 μg/kg (6 mg/d for that same average build man) serum IGF-I ↑ 156→342 μg/L. LR3, then, used systemically by a bodybuilder (characterized by high body surface areas & body weights) probably requires doses above 6 mg/d for equivalent potency to rhIGF-I – however, note that LR3 IGF-I will more likely reduce serum IGF-I because it is an IGF-I analogue designed specifically for rapid clearance & resistance to IGFBP binding.
If you are wondering how rhGH can be superior to rhIGF-I in increasing IGF-I, it is because GH in healthy individuals potently stimulates its synthesis & secretion. RhIGF-I is approved for one rare condition: Severe Primary IGF-I Deficiency (Primary IGFD). Having this condition means that your liver is resistant to GH stimulation of IGF-I. It is, then, a workaround option, to directly administer IGF-I despite its inferiority if otherwise non-primary-IGFD. Its financial expense arises because of market forces, supply & demand, and probably R&D, manufacturing, and transport/supply chain factors.
If LR3 IGF-I is to be used, it should be while bulking (energy in > out) on a per-muscle (not muscle group) rotational basis since it is less potent systemically (due to resistance to IGFBP-3 binding) than rhIGF-I & rhGH.
Split dosing (e.g., 2X/d > 1X/d; b.i.d.; b.d.s.) is superior to once-daily dosing (q.d.) because of the rapid clearance and low biological half-life of LR3 IGF-I that is particularly resistant to IGFBP binding.
LR3 IGF-I is more potent than any other known agent in its propensity to increase gut/visceral organ growth.
LR3 IGF-I's use is limited to a very particular use case – to increase the pool of available myofibers for subsequent hypertrophy in those very muscular bodybuilders that have already reached the limit of their pool (mitogenic vs. myogenic effects). Its propensity to induce hypoglycemia attaches with similar considerations to insulin (rhI) use.
The financial expense and relatively weak potency of LR3 to directly stimulate muscle growth (and very poor performance in anticatabolism, to stave off muscle losses during dieting) limit its versatility tremendously and make it an unlikely choice for the average reader. This one is really for the very advanced bodybuilder.""
since there are people who clearly know what they are talking about.
anyone want to take a shot at dosing levels/methods?
Similar threads
