my igf1 is just 246 and i take 10iu gh daily??

[dick_starbuck]

I did gyno op, took the gland off, I don't get gyno again, anyway I am working lowering my in

Lol you are wrong

"Lol you are wrong". Okay, now that youve aserted that, provide evidence to assert your point.

 

[Dawg86]

I am not trolling or trying to be silly, I am old to aas but not to hgh
And for what I read that 10iu daily has to get your igf1 to higher rang than just 246? Or I am wrong

And for what i understand u mean my igf1 will be in higher in the next weeks?


Edit : I planing to take it for 1 year

Do 10iu for another 6 weeks then test again ur results ur getting now is off the first week at 4iu, hgh is a long game at building up igf-1!!

 

[Nardicus69]

You cutting/in a deficit/eating low carb?

LMFAO not how it works, not even remotely close

I am personally in a 1,000 calorie deficit right now with the assistance of Reta on low carbs as well.

I am doing 1mg of tesamoerlin for 30 days and these are my IGF1 levels:


434 ng/ml Just off 1mg of tesamorelin for 20 days.

Now you could make the argument that I am a hyper responder to this GHRP pharm, but this drug is equivalent to around 2-3IU.

So if OP is doing 10IU of HGH and his levels are below 300, it's most definitely fake.
I wish OP included if he faced sides such as swelling hands carpel tunnel or sleep, or anything as real HGH means real sides most of the time.

 

[Nardicus69]

Your e2 is over 120 but your worried your 250 + igf isn't enough.

Not a single person here can give you a solid answer without knowing what your base level was. Since you didn't get that tested you gonna have to just suck it up.

Get that e2 under control. Are you seeing any symptoms? How long you been using gear?

What's your end goal out of this?

E2 and IGF1 have close to 0 correlation in terms of production

 

[Nardicus69]

Do 10iu for another 6 weeks then test again ur results ur getting now is off the first week at 4iu, hgh is a long game at building up igf-1!!

It's not going to take over a month, in fact if quite literally works within a week LMFAO,
HGH passes through --> the LIVER, the LIVER turns into --> IGF1
This is the sequence on how it works, and based on you said, this whole sequence would be thrown off if you had to wait "weeks" cause last time I checked it doesn't take "weeks" for HGH to go through the liver in fact it takes SECONDS.



“It takes about 1 minute for blood to circulate throughout the entire circulatory system. The time for blood to travel from the left ventricle through the systemic circulation, back through the lungs, and back to the left ventricle is on the order of ~60 seconds (±).”


Source: ClinicalKey

Everyone is in this chat is so misleading its not even funny, OP your stuff is fake I am sorry to tell you.
There is a reason why you can see sides such as enhanced sleep and water retention the same day you use HGH, that is a sign it works right away, and the water retention comes from elevated IGF1 acting on the aldosterone system which regulates water/soduim Homeostatis.

 

[bjjgear]

LMFAO not how it works, not even remotely close

I am personally in a 1,000 calorie deficit right now with the assistance of Reta on low carbs as well.

I am doing 1mg of tesamoerlin for 30 days and these are my IGF1 levels:

View attachment 369972
434 ng/ml Just off 1mg of tesamorelin for 20 days.

Now you could make the argument that I am a hyper responder to this GHRP pharm, but this drug is equivalent to around 2-3IU.

So if OP is doing 10IU of HGH and his levels are below 300, it's most definitely fake.
I wish OP included if he faced sides such as swelling hands carpel tunnel or sleep, or anything as real HGH means real sides most of the time.

Homie I wouldn’t be worrying about OP, I’d be worried about turning into Fred Flinstone in a couple of years at your current IGF-1 production on that weak ass Tesa shit. May want to get that looked at

 

[Nardicus69]

Homie I wouldn’t be worrying about OP, I’d be worried about turning into Fred Flinstone in a couple of years at your current IGF-1 production on that weak ass Tesa shit. May want to get that looked at

Bro ….
You do realize Acromgelay or CranioFacial growth comes from 700+ IGF1 right ?

And if Tesa is so weak, why do I have the same levels as someone taking 4IU of HGH ?????

So which one is it ????, is too strong that I’m going to turn into “Fred flingstone” or is “weak” as you stated???

You just contradicted yourself in your own statement without realizing it and it truly highlight your low IQ intelligence pls stop responding your jus making yourself look more stupid n it shows you have 0 understanding of the endocrine system and the mechanism on how it works.

And another thing you do realize the whole point of taking HGH is to have high IGF-1 right ? So if I’m already getting high IGF-1 how is it weak I mean tha labs prove it clearly. I genuinely think this convo is above your scope.

N it’s sucks there is a lot of people on this forumn like you who use bro science + ego to reason and lack critical thinking n can’t even comprehend a research paper.

I even provided source which your probs not even gonna open cause your not able to decifer them which is genuinely sad. I’m simply telling OP what it is while helping him and the low IQ people are saying things that don’t even mechanistically make sense from a Biology POV.

 

[Billbo98]

You’re a horrible responder or you have some stepped on GH

 

[Nardicus69]

You’re a horrible responder or you have some stepped on GH

Not a horrible responder cause if he was he would have known by birth and or wouldn’t even go through a puberty to begin with. His HGH is fake

 

[Elektrobot]

You do realize Acromgelay or CranioFacial growth comes from 700+ IGF1 right ?

Your z score is 2.7, which is pushing a boundary.

You should carefully determine your risk tolerance


From posts that I've read here, acromegaly growths happen above a z score of 3.0, which is variable based on age and igf range given by the lab running the test

But LabCorp defines acromegaly as starting at a z-score of 2.0

• A Z-score (number of standard deviations from the mean) >2.0 is compatible with GH excess (eg, suggestive of acromegaly or consistent with over treatment with GH).

Quest Diagnostics: Test Directory

testdirectory.questdiagnostics.com

 

[Nadix]

Acromegaly growths happen above a z score of 3.0, which is variable based on age and igf range given by the lab running the test

For someone who is 17, an igf of 700 might have their z score at +2.5

For someone who is 25, an igf of 700 might have their z score at +5

A z-score above 3 is medically diagnosed as acromegaly, and you can expect odd bone and tissue growths to start developing.

Follow the z score for acromegaly concerns.

can u tell me plz what’s my z score ? 29 old , 246 igf1
sry i don’t know how to calculate z score thnx in advance

 

[Elektrobot]

can u tell me plz what’s my z score ? 29 old , 246 igf1
sry i don’t know how to calculate z score thnx in advance

The first thing to do would be to look at your test results and see if the lab provided you a z-score.

If not, I think there is a way to calculate it. I've seen Ghoul do it in a few posts. I gave it a try but was inaccurate with the formula I found.

 

[Nardicus69]

Acromegaly growths happen above a z score of 3.0, which is variable based on age and igf range given by the lab running the test

For someone who is 17, an igf of 700 might have their z score at +2.5

For someone who is 25, an igf of 700 might have their z score at +5

A z-score above 3 is medically diagnosed as acromegaly, and you can expect odd bone and tissue growths to start developing.

Follow the z score for acromegaly concerns.

Yea fair enough this part is correct but to say 3+ = acromegaly is just blatantly false and there is far more nuance here:

1.) You would legit have to have a statistically high Z score (elevated IGF-1) for YEAR’S like like 5 - 10 years + n to be fair, most people here can even afford to source enough to maintain a Z score as you stated for that duration unless planning on open BB.

2.) The human body wouldn’t even allow for a Z score to stay as elevated due to receptor down regulation over time meaning 10IU 4 years ago isn’t going to hit the same as 10IU tomorrow. This point alone reinforces the how much you would have realistically spend to even maintain and at that point you would to force it to happen.





TDLR:

The length and dose increase matter more

 

[Nardicus69]

can u tell me plz what’s my z score ? 29 old , 246 igf1
sry i don’t know how to calculate z score thnx in advance

An IGF-1 of ~246 ng/mL at age 29 is basically normal and fully achievable naturally, with no enhancement required.

it’s likely 0.7-1 =-0.3 Z Score

Which point to the source like I said previously being fake

 

[Nadix]

An IGF-1 of ~246 ng/mL at age 29 is basically normal and fully achievable naturally, with no enhancement required.

it’s likely 0.7-1 =-0.3 Z Score

Which point to the source like I said previously being fake

i use optitropin hgh

 

[Elektrobot]

You would legit have to have a statistically high Z score (elevated IGF-1) for YEAR’S like like 5 - 10 years

You are mistaking the timeline in which people get a diagnosis for the timeline of when symptoms begin

Symptoms can begin as early as 6 months (at a much higher z score than 3). On average, it takes many years for someone to seek medical attention for it. They often confuse it with genetics or aging.

10IU 4 years ago isn’t going to hit the same as 10IU tomorrow.

Which is why z score changes with age. The older you get, the less it takes

 

[Tk1000]

Acromegaly has nothing to do with IU.

I’m going to try and break this down as simply as I can. Because despite not “personally” witnessing acromegalic changes, what I’m going to say is 100% certain, backed up with a mountain of evidence in medical literature building over the last 50 years.

If some decide acromegaly is a “myth”, “blown out of proportion”, or the classic “this doesn’t apply to me because the study subjects weren’t 43.5 year old 5’ 7” bodybuilders who injected rHGH between 7:12-7:19AM.” then IDGAF.

Suffer and don’t say you weren’t warned,

Acromegaly has nothing to do with IU.

It’s only caused by IGF-1. IGF regulates cellular growth. And we know people using the same IU have IGF-1 levels all over the place. 2iu doesn’t mean you’re safe, and 10iu doesn’t mean you’re at risk.

It’s all about the Z score, how far above you are normal IGF-1 for your age. Without fail even those with a pituitary tumor squeezing out a ton of growth hormone, when IGF-1 is knocked down with meds to normal appropriate levels, acromegaly stops progressing.

Specifically how far above the upper limit of normal you are FOR YOUR AGE.

Acromegaly is insidious. The average time to diagnosis is 7 years. 60% of the time it’s first identified by a DENTIST, EYE DOCTOR, or SLEEP APNEA SPECIALIST, since they’re trained to look for it.

The lowest Z score acromegaly is typically diagnosed at is 3.5.

It could take 2iu or 15iu to reach 3.5.

At a continuous Z 3.5:

Soft tissue always changes first. By 1 year at that level, your organs have changed sufficiently organomegaly can be seen on an MRI. Even the slowest moving acromegaly has unmistakable facial features an acromegaly specialist can visually identify after 12-24 months of Z 3.5, But almost no one else around you os likely to notice anything that sets off alarm bells. Maybe your shoes and rings don’t fit anymore so you catch it early.

But according to the experts, it’s not until someone who knows what to look for, like a dentist who notices your fucking teeth don’t line up anymore, identifies acromegaly after 7-10 years of elevated IGF-1. Imagine how much soft tissue has grown, how much your nose has changed, how many god damn whacks in the face with the ugly stick you must’ve gotten by the time your JAW EXPANDS.

Acromegaly doesn’t happen below Z 3. At least after an exhaustive review, I can’t find a single case of it below Z 3.

By Z 4 it’s almost always pathological. The higher above that the faster the changes come on.

So check your Z. If it’s above 3 and you keep it elevated like that for over 6-12 months, you’re probably developing acromegaly. Maybe very slowly at the lower. Over 4 and it’s nearly certain you’ll be fucked up after two years, including skeletal changes that may cause permanent joint issues.

That’s the main reason labs have an adult IGF Z score. Endocrinologists don’t really need them. It’s to give primary care doctors a simple number that automatically adjusts with age that tells them if the rHGH treatment adult patient they’re monitoring between endo appointments is slipping into the danger zone.

Keep Z below 3 if you’re using rHGH long term. Below 2 if you feel safer staying in the physiological range.

Thread 'IGF-1 Help'

Oct 16, 2025

I’m on H36 from SSA. Been using 8ius for 12 weeks. For the past 7 weeks been using 4ius. I tested my IGF-1 an hour after my 4iu daily injection but it shouldn’t matter correct? Since it’s cumulative, and have had consistent dosing for week.

Fuck me, does this mean my 3 kits of hgh are useless and I’ve been fucking around for months

What’s concerning is it’s SSA.
I should get a GH serum test. But do y’all think it’s possible this is how I react to 4ius? Seems impossible

• Deadpool99
• Replies: 33
• Forum: Serum Blood Testing

• 

See the quote from @Ghoul for z-score. Also read the linked thread with a similar situation to yours. Diet, e2, aas use (tren), liver function/issues, thyroid can all affect your igf1 levels.

 

[Elektrobot]

i use optitropin hgh

You really should just stop using it, wait 2 weeks, and go test your natty igf-1

That will give you more insight into your conversion rate. For all you know, your natty number was 120 and you have now doubled it.


If your curiosity is the potency of your hgh vials, you can shoot 10iu IM and 2 hours later get a blood draw to check your GH blood serum levels

30 or above is considered equivalent to pharma strength

Below 30, you would have to adjust your dosing compared to pharma to get similar results.

 

[Nardicus69]

i use optitropin hgh

I’d have to take a look into them as I have never used them. n tbh HGH is the number 1 most faked pharmaceutical in the world more faked than Primo n people love talking about primo which funny cause HGH from a molecular level is like 10x harder to make/ produce than primo by landslide it’s not even funny.

It happens to most people but will take a look into the certs n send em a recent email regarding there Janoshik testing n also do your vials look weird visually ?

 

[Nardicus69]

Thread 'IGF-1 Help'

Oct 16, 2025

I’m on H36 from SSA. Been using 8ius for 12 weeks. For the past 7 weeks been using 4ius. I tested my IGF-1 an hour after my 4iu daily injection but it shouldn’t matter correct? Since it’s cumulative, and have had consistent dosing for week.

Fuck me, does this mean my 3 kits of hgh are useless and I’ve been fucking around for months

What’s concerning is it’s SSA.
I should get a GH serum test. But do y’all think it’s possible this is how I react to 4ius? Seems impossible

• Deadpool99
• Replies: 33
• Forum: Serum Blood Testing

• 

See the quote from @Ghoul for z-score. Also read the linked thread with a similar situation to yours. Diet, e2, aas use (tren), liver function/issues, thyroid can all affect your igf1 levels.

Yea true, but 10IU = 246 is most definitely not any of the issues mentioned mostly far from it. N it wouldn’t put it on vitamin deficiency n so on as OP is going for testing which implies to me that he has adequate diet and nutrition. The fact his levels are in natty range point to his liver being okay in that regards, and more so point to the source being fake IMO. They can all affect your igf1 but where talking about a huge margin here.