May be the end of the line on gear for me. Having LUTS saw the urologist and he said my prostate is enormous.

tadalafil does not lower PSA but it will improve urinary symptoms from BPH by relaxing smooth muscle As mentioned above, it is FDA approved and the typical dose is 5mg a day.
What smooth muscle in this case is affected? Sorry if that is a stupid question, but I do not know much about urinary issues.
 
What smooth muscle in this case is affected? Sorry if that is a stupid question, but I do not know much about urinary issues.
I'm going to cheap out and cite ChatGPT's response.

Cialis (tadalafil) doesn’t just work on blood vessels.
It relaxes several kinds of smooth muscle in and around the prostate, bladder, and urethra — the same area that controls how urine flows out.

Here’s what that means in more everyday terms:
  1. Inside the prostate
    • The prostate has muscle fibers that can “squeeze” the urethra (the tube urine passes through).
    • When these muscles are tight, it’s harder to urinate — like a kink in a hose.
    • Cialis relaxes those muscles, opening the channel so urine flows more easily.
  2. At the base of the bladder (the bladder neck)
    • There’s a ring of muscle that acts like a valve — it holds urine in until it’s time to go.
    • In men with BPH, that valve can stay partly closed all the time.
    • Cialis helps that valve relax at the right time, so the bladder empties with less straining.
  3. Along the urethra itself
    • The walls of the urethra have their own thin layer of muscle.
    • Relaxing it makes the tube less constricted, again helping urine move more freely.
  4. The blood vessels feeding all these areas
    • Cialis widens them too, improving blood flow and oxygen to the tissues.
    • Better circulation helps the area stay healthy and function smoothly.
  5. The bladder wall (the “pump”)
    • Cialis doesn’t directly make the bladder squeeze harder or weaker,
      but it may help calm an overactive bladder by reducing nerve “noise.”
 
Let us know how it goes.

I wake up once or twice at night to pee, very occasionally 3X, but I am late 50s and have a bad habit of drinking things in bed prior to going to sleep, so . . .
Nevertheless, I am sure I have something going on with my prostate, because it takes me longer to pee than it did when I was youn

I'm going to cheap out and cite ChatGPT's response.
lol thats what i was going to do as well
 
Let us know how it goes.

I wake up once or twice at night to pee, very occasionally 3X, but I am late 50s and have a bad habit of drinking things in bed prior to going to sleep, so . . .
Nevertheless, I am sure I have something going on with my prostate, because it takes me longer to pee than it did when I was younger.
same boat as you, 57 prob wake up 3-4 times to piss. I do consistently drink a gallon of water a day so I like to think that has something to do with it. I'm sure its enlarged happens to everyone as we age. Last PSA was 1.2, going to get another in 3months. I'm not coming off trt though thats not an option for me.
 
Yes. FDA-approved for it in fact. I've still got some prostate enlargement due to prostatitis and it caused double voiding and decreased flow strength. Added 5mg tadalafil daily and both issues resolved. I suspect if my condition were worse, it might not completely resolve issues, but it would greatly reduce them.

I've been on tadalfil 5mg a day for over 5 years and am on rapaflo - silodosin which is the strongest alpha blocker and I still pee as if I have a large obstruction. Eventually the meds stop working and you have to pay the piper with an intervention. Sooner rather than later is my opinion.
 
Did they explain why "rabidly against" (not just a little against) the use of finasteride?

Seems effective for BPH but I guess your urologists were weighing that sexual side effect and mental wellness (?)
Finasteride can mask prostate cancer by artificially lowering your PSA is what I was told by a doc. It will shrink your prostate over time but a lot of docs dont like the risk to reward ratio, especially if your psa is already elevated.
 
same boat as you, 57 prob wake up 3-4 times to piss. I do consistently drink a gallon of water a day so I like to think that has something to do with it. I'm sure its enlarged happens to everyone as we age. Last PSA was 1.2, going to get another in 3months. I'm not coming off trt though thats not an option for me.
61 here and about the same. My doc doesnt sweat it too much unless you start having an increasing psa or difficulty urinating. Prostate issues and age go hand in hand...yes, gear aggravates the situation but going without trt brings a whole new lvl of suck into things. Apparently testosterone doesnt actually jack with the prostate (which kinda makes sense. Old guys natural production drops but they still get bph) but the aromatizing of it does. Also DHT, estradiol, and progesterone all chip in...all those wonderful extra little benefits from running gear.

Man, getting old ain't for the weak of heart!
 
61 here and about the same. My doc doesnt sweat it too much unless you start having an increasing psa or difficulty urinating. Prostate issues and age go hand in hand...yes, gear aggravates the situation but going without trt brings a whole new lvl of suck into things. Apparently testosterone doesnt actually jack with the prostate (which kinda makes sense. Old guys natural production drops but they still get bph) but the aromatizing of it does. Also DHT, estradiol, and progesterone all chip in...all those wonderful extra little benefits from running gear.

Man, getting old ain't for the weak of heart!
Yeah, getting old sure does suck. What are your go to compounds? For me test, deca and a dht these days. Can't really run high doses anymore, I just stay on a trt plus protocol and get labs every 3 months.
 
Test and low dose deca for the joints. I grab labs about every 3-4 months myself...about time again. DHT worries me a bit on what it can affect so I steer away from it. Anything else fucks my BP up enough its not worth the risk. I dont mind the getting old so much as the damn baggage that comes with it...golden years my ass! Only gold Ive found is the one crown in my mouth.
 
Another update on this. Definitely have obstruction due to BPH. I am getting an Aquablation (it's an ablation of prostate tissue with a high powered water jet) done asap and am just waiting to be scheduled by the surgeon's office (we met this week).

This has been happening FOR A LONG TIME as I have a wide mouth diverticulum on my bladder and that takes years and years and years to develop.

To recap I abused testosterone and other AAS but mainly testosterone and dianabol beginning 17 years ago in my late 20s for 3 years. I spent the majority of those 3 years on testosterone. I was completely natural for the next 10 years and then began TRT - I also cycled a bit as well with primo and higher levels of testosterone during TRT years but most of the time was on true TRT. This means that my BPH obstruction began in my late 20s/early 30s for this diverticulum to have time to form and time has pushed it over the edge. I'm convinced it was the gear and there is a lesson there. Avoid my mistakes and don't get a coronary artery calcification and an enlarged prostate in your 40s.

The interesting thing is that every urologist I have met with consulted with procedurally on this journey has told me to stay on testosterone and were rabidly against the use of finasteride.
What was your “mistake”? I am actually 41 and will be doing my first cycle in December and will end it with just staying on TRT and rolling with high side of normal on the numbers. Not planning on taking tren or anything like that. Just testosterone, Anavar, and GH.
Which I been in GH for about 8 months now. 2ius a night. I’m hoping by starting so late I’ll avoid some issues
 
Last edited:
My mistakes were using too much testosterone for too long. The amount of E2 and DHT 500+ mg of testosterone per week generates is off the charts. Also it wasn't as common back then to control these metabolites. We also thought it was normal to do 500 test as a first cycle and 500 test + 600 eq as a second. Totally insane


What this led to was unchecked dislipidemia and prostate enlargement. Had I known better 15 years ago I would have used statins or not cycled at all. I also would have used lower amounts of testosterone and higher amounts of less androgenic anabolics.

Anavar is only mild from an androgenic point of view. It will destroy your lipids if you don't control them.
 
Just be careful with these BPH operations. Urologists love to drill out prostates because it is a huge revenue source for them. Nocturia often remains after the operation because it is associated with other sleep issues.

I get up at least 3 times a night and my stream sucks but my dick works and I want more kids so I just live with it.
 
Just be careful with these BPH operations. Urologists love to drill out prostates because it is a huge revenue source for them. Nocturia often remains after the operation because it is associated with other sleep issues.

I get up at least 3 times a night and my stream sucks but my dick works and I want more kids so I just live with it.

I have zero nocturia but my bladder is slowly becoming damaged. It's not a quality of life issue, it's a long term health issue... at least for me. I also have children... I don't want anymore. I want to still ejaculate and aquablation has a 90% chance of maintaining that bc. 97% chance where I am going. I also have a smaller prostate which seems to be helpful with that.

I also can barely piss without Rapaflo if I have had an orgasm within the last 24 hours.
 
I just started a ten-day course of both Prostamax and Vesilute. Pretty fascinating if you dig into BPH and the intended effects of the bioregulators (moreso Prostamax in this case). I was already on Tamsulosin 0.8mg for a while, which helped a little with having to get up in middle of night. Recently switched to Silodosin 8mg, which is having a much stronger effect, to the point I can absolutely feel the pressure/bottleneck in prostate area when urinating. I'll report back in a few weeks if I find any relief from the bioregulators. It takes time for tissue to rearrange itself (supposedly). I'll try anything to avoid both DHT blockers (I don't do well, even low dose) and especially surgery or any kind of invasive procedure.
 
Back
Top