You can do 1 cc a week. A front load would be e3d for two weeks and once a week from then on. B vitamins are water soluble and cannot build up in the system... they can be over dosed in a single pin (you could pin 30cc's at once) to have issues, but there is no accumulation over a week to speak of even im. Vitamins like d and e are fat soluble and can cause issues when built up over time. B's just get pissed right out; hence the useless nature of oral b vitamins. In and out. Muscle absorption is needed for a bleed.