Although his work as a pioneer in this area the rest of medicine shamefully blacklists (anti-aging), by the early 2000’s, a series of accidents resulting in giving patients acromegaly with rHGH got endocrinologists to not only dose by IGF-1 instead of weight, they realized it was necessary to keep IGF within 2 standard deviations (later the “Z score”) to prevent acromegaly.
Thanks to a “misunderstanding”, probably by his primary care doctor, he was kept on 4mg (12iu) instead of the 1.5mg (4.5iu) he was supposed to be lowered to in order to stay in range for his age. This is probably why Z scores started appearing on lab tests, so primary care docs could quickly identify a problem. IGF 800 is fine at 13, so that may be why the primary care doctor wasn’t alarmed seeing that number despite the patient being 22.
No action was taken after testing showed IGF-1 was over 800. He was on that 12iu dose for just 1 year longer than he should have been, developing an overbite and fucked up skeleton requiring multiple surgeries. ONE YEAR.
(1mg=3iu)
View attachment 363446
We had someone here who got an IGF of 70o not long ago, and he was being congratulated.
I don’t know his age, but I assume older than 22, making 700 far worse than 800 at 22 because Z score for a given IGF goes up quickly every year, and therefore changes, occur faster.
So remember, if you’re using long term, keep Z under 3.
I’m certain there are guys out there right now running cheap rHGH year round, who either don’t know their IGF-1, or think their 800+ is great and unwittingly growing a deformed skeleton we’ll hear about in some horror story in a year or so.