Ideal HGH Protocol - Muscle Gain

[JimCollins]

HI Guys

I’ve read many previous threads but wanted to resurface this topic. I’m currently on 4iu/day of pharma HGH. I just recently switched from pinning in my abdominal region to my delta as I was told this would be more beneficial. I’m pinning in one full dose around 3:00am, go back to bed for two hours, eat a preworkout meal and then train around 6:00am.

I continue to see that the best protocol for HGH is a split between pre and post workout? Is this true? If so, how do you suggest meal timing (should I workout fasted....only with a protein shake, etc?). How would I time my post workout meal and shake? Also, would I need to eliminate my intra workout carb drink (Karbolyn)?

Please help me determine the most ideal protocol for muscle gain taking into consideration early morning training.

 

[mands]

Nice read here. Take a look. It's 15 pages, I would suggest you read it.

The Most Effective Growth Hormone Protocol for Hypertrophy - MESO-Rx

mands

 

[Montego2]

Nice read here. Take a look. It's 15 pages, I would suggest you read it.

The Most Effective Growth Hormone Protocol for Hypertrophy - MESO-Rx

mands

Been a while old man [emoji6]

 

[mands]

Been a while old man [emoji6]

Haha! What it's been so long you forgot your password and started a new handle?

mands

 

[Wunderpus]

HI Guys

I’ve read many previous threads but wanted to resurface this topic. I’m currently on 4iu/day of pharma HGH. I just recently switched from pinning in my abdominal region to my delta as I was told this would be more beneficial. I’m pinning in one full dose around 3:00am, go back to bed for two hours, eat a preworkout meal and then train around 6:00am.

I continue to see that the best protocol for HGH is a split between pre and post workout? Is this true? If so, how do you suggest meal timing (should I workout fasted....only with a protein shake, etc?). How would I time my post workout meal and shake? Also, would I need to eliminate my intra workout carb drink (Karbolyn)?

Please help me determine the most ideal protocol for muscle gain taking into consideration early morning training.

What about pinning delts is allegedly "more effective"?

Pinning pre/post really depends on goals and the overall dose. In reality, it doesn't matter MUCH... However, I like doing it post weight training a bit more than pre, unless using insulin.

I think the takeaway here is that timing doesn't matter a TON as IGF-1 levels will be peaked throughout the day.. It only matters if you're taking like 4+ius per day, and would only matter in the sense of splitting your doses.

 

[hghlover]

From talking with an endocronologist, splitting your daily dose into two shots, am and pm, instead of one big daily shot, can increase IGF 1 levels by up to 50%

Hgh serum levels also go up

 

[mands]

From talking with an endocronologist, splitting your daily dose into two shots, am and pm, instead of one big daily shot, can increase IGF 1 levels by up to 50%

Hgh serum levels also go up

Actually one bolus dose of GH will increase your IGF-1 to a higher level than splitting your dose.

mands

 

[MrRoidsen]

I've been using HGH for around 8 months, dosage range from 6 to 10iu ed, and never got any CTS symptom. Is it bunk?

 

[janoshik]

From talking with an endocronologist, splitting your daily dose into two shots, am and pm, instead of one big daily shot, can increase IGF 1 levels by up to 50%

Hgh serum levels also go up

It doesn't matter whether you use it once daily or multiple times in regard to IGF-1. GH serum levels are higher with a single shot.

Effect of Growth Hormone Administration Frequency on 24-hour Growth Hormone Profiles and Levels of Other Growth Related Parameters in Girls With Turner's Syndrome. Dutch Working Group on Growth Hormone - PubMed
Growth Response and Levels of Growth Factors After Two Years Growth Hormone Treatment Are Similar for a Once and Twice Daily Injection Regimen in Girls With Turner Syndrome. (Dutch Working Group on Growth Hormone) - PubMed
Final Height in Girls With Turner's Syndrome Treated With Once or Twice Daily Growth Hormone Injections. Dutch Advisory Group on Growth Hormone - PubMed

 

[hghlover]

I've been using HGH for around 8 months, dosage range from 6 to 10iu ed, and never got any CTS symptom. Is it bunk?

No sides at 10 iu sounds insane

 

[mands]

@hghlover systemic IGF-1 levels absolutely are higher with one bolus dose vs. splitting the same iu amount. @janoshik is wrong about the igf-1.

mands

 

[wildfuchs]

@hghlover systemic IGF-1 levels absolutely are higher with one bolus dose vs. splitting the same iu amount. @janoshik is wrong about the igf-1.

mands

could you show evidence/explain why?

 

[Wunderpus]

Another interesting study to review regarding the "bolus dose vs. pulsatile dosing" question:
Pulsatile Versus Continuous Intravenous Administration of Growth Hormone (GH) in GH-deficient Patients: Effects on Circulating Insulin-Like Growth factor-I and Metabolic Indices - PubMed

 

[mands]

Another interesting study to review regarding the "bolus dose vs. pulsatile dosing" question:
Pulsatile Versus Continuous Intravenous Administration of Growth Hormone (GH) in GH-deficient Patients: Effects on Circulating Insulin-Like Growth factor-I and Metabolic Indices - PubMed

This is actually pulsatile vs. continuous infusion. But, still a good study.

@hghlover I’ll dig up a study explaining the pulsatile vs. one bolus dose.

mands

 

[Montego2]

Haha! What it's been so long you forgot your password and started a new handle?

mands

Yeah. I think I might have posted here ten or fifteen times in the past so, forgot.

You still use wickr?

 

[JimCollins]

Nice read here. Take a look. It's 15 pages, I would suggest you read it.

The Most Effective Growth Hormone Protocol for Hypertrophy - MESO-Rx

mands

Thanks!

 

[mands]

could you show evidence/explain why?

Let me clear here so members aren't thinking one dose is the best way to maximize hypertrophy. As studies would suggest that pulsatile injections would be in favor(but you need to let igf-1 levels return to base line or near base line before dosing again).

They have also shown that using a higher dose will increase gh serum and igf-1 serum quicker.

Pharmacokinetics and Pharmacodynamics of GH: Dependence on Route and Dosage of Administration - PubMed

mands

 

[Wunderpus]

This is actually pulsatile vs. continuous infusion. But, still a good study.

@hghlover I’ll dig up a study explaining the pulsatile vs. one bolus dose.

mands

As you know, I'm partially retarded. But, what other determination besides "pulsatile doses are more effective than bolus doses" can you decipher from this quote "These data indicate that small but frequent iv boluses and continuous infusion of GH are equally effective in generating an increase in IGF-I in GH-deficient patients, whereas the same amount of GH given as two large boluses results in a significantly smaller increase in IGF-I."?

 

[mands]

As you know, I'm partially retarded. But, what other determination besides "pulsatile doses are more effective than bolus doses" can you decipher from this quote "These data indicate that small but frequent iv boluses and continuous infusion of GH are equally effective in generating an increase in IGF-I in GH-deficient patients, whereas the same amount of GH given as two large boluses results in a significantly smaller increase in IGF-I."?

You have to look at the timing and that this study was done with IV administration and not IM or SC. These all are contributing factors.

Serum GH and IGF-1 will rise faster and fall faster with the two larger doses vs. the eight and continuous infusion. Making the average serum levels lower.

mands

 

[janoshik]

And this, children, is why we leave interpreting science to somebody whose education is not the one of a PE teacher. Case rested.