High Responder t> 15ng/dl, E2 90, hct 51.8%. Crashing on taper. Need protocol advice please

wildwoodmc

New Member
Reposting here as it seems to be accurate for my post: https://thinksteroids.com/community...hing-on-taper-need-protocol-advice.134436815/


Stats
Age: 53
Weight: 84.5 kg
Body Fat: 22% (approximate)

History: Various blasts and cruises over the last 2 years. Stable on this current dose (~187mg/wk) for the last 6 months.

Current Protocol: 187.5 mg/week (Test C 250mg/mL) split into 3 injections.

Lifestyle: 2–4 hours training/week.
Not best diet (protein and fibre solid but still too much sugar, fat, salt, and refined carbs).
Chronic dehydration (under 1 liter of water per day).

The Context (Mental Health and Baseline)
I have been using this higher dose as a quick hack to stay on top of mounting personal stress and pressure. The Test has definitely helped my libido and drive stay alive during a very dark period where I feared a depressive slide.

My natural baseline (pre-TRT) was very poor:
Free T: 14.1 pmol/L (Below reference range)
SHBG: 47 nmol/L

Because my GP has zero experience with TRT, I have been navigating this on my own.
Given my 2-year history of blasting and cruising, I believe my neurochemistry is heavily adapted to high androgen levels, which is likely why my previous attempts to taper felt so brutal.

The Problem
I am a massive high-responder. At 187.5mg/week, my levels are pinned at >15ng/mL. When I previously tried to taper by 20% (down to 150mg/week), I crashed hard—specifically libido and mental well-being—though my gym performance stayed decent. I want to get healthy and bring these markers down, but I am looking for a way to avoid that depressive hole.

Latest Lab Results (Feb 2026)

Total Testosterone: >15.00 ng/mL (Ref: 1.93 – 7.40)

Estradiol (E2): 90.0 pg/mL (Ref: 11.3 – 43.2)

Hematocrit: 51.8% (Ref max: 48.6%)

eGFR (Kidney): 67 mL/min (Ref: >90)

Creatinine: 12.2 mg/L (Ref max: 11.7)

HOMA-IR: 2.34 (Rising insulin resistance)

Vitamin D: 28.3 (Low)

Folate (B9): 2.9 (Critically Low)

Questions for the Forum

1. The Crash: Was the previous crash likely due to the T:E2 ratio shifting too fast after 2 years of being enhanced? How do I drop dose without the mental and libido side effects?

2. E2 Management: At 90 pg/mL, should I use a micro-dose AI (0.125mg) while I slowly lower the Test dose to stabilize the transition?

3. Health Priority: With an eGFR of 67 and Hematocrit of 51.8 after 2 years of B&C, how urgent is this? Will 4L of water and lower salt pull these back, or do I need a phlebotomy?

4. Nutritional Link: Should I fix the Folate and Vitamin D first to stabilize my mood before I touch the Testosterone dose?

5. The Micro-Taper: Has anyone successfully used very small drops (e.g., 5-10mg a week) to get off a cruise without the brain noticing the dip?

I am trying to move away from using TRT as a crutch for stress, but I need a sustainable exit strategy. I have nowhere else to go for advice other than this forum as a starting point.

I appreciate any experience you guys can share. I need to get off the "stress-crutch" without falling apart.
 
I'm no expert but I think you have to dial in the diet first (hydration here too). I didn't see mention of a GLP1 so I woulod get that in the mix. If you get the diet right and BF down I think a ton of this self resolves.

So if that were my situation, I'd keep the T where it is, add more AI to lower my E2. Fix my diet and add in Tirz. Once your diet is tight and BF is manageable then I'd taper down the T to a lower cruise level.
 
I'm no expert but I think you have to dial in the diet first (hydration here too). I didn't see mention of a GLP1 so I woulod get that in the mix. If you get the diet right and BF down I think a ton of this self resolves.

So if that were my situation, I'd keep the T where it is, add more AI to lower my E2. Fix my diet and add in Tirz. Once your diet is tight and BF is manageable then I'd taper down the T to a lower cruise level.
Hey thanks for this. I have been intermittent on Ozempic 0.5 per week. I just posted a photo and maybe 19%. Def not jacked so clearly something is off from not training hard enough as well.
 
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