Filtering finished oils

[Photon]

Random crap to share.

For 50-60ml, get a normal caulking gun
For 20-40ml, get a 1/2 sized caulking gun (I've been using this. Permatex The Right Stuff Caulking Gun - Model 800368)
For 5-10ml, get a glue gun from AliExpress (<$5)
For <5ml, are you serious?

 

[narta]

Random crap to share.

For 50-60ml, get a normal caulking gun
For 20-40ml, get a 1/2 sized caulking gun (I've been using this. Permatex The Right Stuff Caulking Gun - Model 800368)
For 5-10ml, get a glue gun from AliExpress (<$5)
For <5ml, are you serious?

You can probably avoid all that and filter with 10ml syringe by hand

 

[Photon]

You can probably avoid all that and filter with 10ml syringe by hand

Totally agree.
Just sharing options for those who are planning to start filtering.

I used 30ml to filter my UGL oils while waiting for my raws to arrive and get tested. Planning to stick to smaller brews in future so a 3ml syringe is probably sufficient without any gun.

 

[UberLOL]

Not sure this has been shared but I found this informal study comparing 13mm and 4mm PES filters that suggests a volumetric loss of 28.5iu and 5-7iu respectively.

https://www.aliexpress.com/item/1005008493243482.html < found these 4mm PES filters

 

[Ghoul]

Not sure this has been shared but I found this informal study comparing 13mm and 4mm PES filters that suggests a volumetric loss of 28.5iu and 5-7iu respectively.

https://www.aliexpress.com/item/1005008493243482.html < found these 4mm PES filters

Great price on those filters, good find.

"Air purge" always bothered me because the foaming effect creates the air/water interface we know facilitates aggregate creation, so better to use a low hold up volume filter like this, or, flush the filter with an amount of BAC equivalent or greater than the holdup volume through the filter to get the rest out.

And of course, a greater volume of BAC used to reconstitute, like 2 or 3 ml cuts down the loss to half or a third as well.

 

[Jaruk]

Any way to guarantee that aliexpress filters are sterile other than coming in individual packages?

 

[Ghoul]

Any way to guarantee that aliexpress filters are sterile other than coming in individual packages?

Not really unfortunately.

Even if one or two tested sterile, that's no guarantee, unlike an FDA regulated source.

That said, radiation sterilization is practically free for the manufacturer, so if they're individually packaging them it's likely they're not faking the sterilization.

On the other side of this, of the peptide samples tested by Jano, 20%+ fail sterility tests. Even commercially produced peptides by lab suppliers in the US are recommended to be sterile filtered before use in any application that matters, like experiments on living organisms some.

So these filters are unlikely to make things worse than not filtering at all, like most.

 

[mammajamma]

Great price on those filters, good find.

"Air purge" always bothered me because the foaming effect creates the air/water interface we know facilitates aggregate creation, so better to use a low hold up volume filter like this, or, flush the filter with an amount of BAC equivalent or greater than the holdup volume through the filter to get the rest out.

And of course, a greater volume of BAC used to reconstitute, like 2 or 3 ml cuts down the loss to half or a third as well.

I don't think that applies to oils

 

[Ghoul]

I don't think that applies to oils

No it doesn't. The report was related to peptides, and I wouldn't use anything smaller than 25mm for oils, the loss isn't significant for those.

 

[UberLOL]

I don't know if this is mere pedantry but would a higher or lower gauge needle be better for reducing loss/waste?

Perplexity says higher gauge retains less fluid, which makes intuitive sense. However, chatGPT says lower gauge = faster flow = less retention, and that higher gauge leads to 'capillary action' inside the needle?

 

[AlexDavis43]

I don't know if this is mere pedantry but would a higher or lower gauge needle be better for reducing loss/waste?

Perplexity says higher gauge retains less fluid, which makes intuitive sense. However, chatGPT says lower gauge = faster flow = less retention, and that higher gauge leads to 'capillary action' inside the needle?

It's really not gonna be a lot of volume either way. You can also dilute it more so whatever is left has less active ingredient.

 

[UberLOL]

Handy guide to choosing syringe filters, common particle sizes, which filters react or are compatible with what:

How to Select a Syringe Filter and How to Use it? (2020 Guide)

How to Select a Syringe Filter and How to Use it? (2020 Guide) Knowledge of Syringe Filter Membrane, Pore Size, Diameter, and Usage Guide In this article: As a Syringe Filters ManufacturerWhat is a syringe filter?How to Select a Right Syringe Filter?Syringe Filter Bestsellers...

airekacells.com

 

[Photon]

Ive been using Ultra spec which comes with rubber stoppers..however recently i chanced upon a source who used really nice looking clear silicone gel stoppers for their oils.

Are there any Ultra spec like sterilized vials which comes with silicone stoppers instead? The only ones i could find require manual crimping/sealing..

 

[Ghoul]

Ive been using Ultra spec which comes with rubber stoppers..however recently i chanced upon a source who used really nice looking clear silicone gel stoppers for their oils.

Are there any Ultra spec like sterilized vials which comes with silicone stoppers instead? The only ones i could find require manual crimping/sealing..

Finally found these:

ALK SEV1020

These vials have the same certifications for sterility, endotoxin, particulates, as the Ultra Spec glass but use a Fluortec barrier film stopper.

These are the ultimate for long shelf life

west flurotec coated barrier film stoppers

Upgrade your vial containment with FluroTec® Barrier Film Stoppers from West Pharma. Superior design for improved drug packaging and patient safety.

www.westpharma.com

You have to click "In stock" to see the list of available products. The letter on the end designates the color of the cap. 25 vials in a pack.

Best price I could find was here:

ALK Sterile Filling Vials | Sterile Vials | BioPharm World

Shop for the ALK Sterile Filling Vials and other Sterile Vials at BioPharm World

www.biopharmworld.com

 

[Sampei]

Finally found these:

ALK SEV1020

These vials have the same certifications for sterility, endotoxin, particulates, as the Ultra Spec glass but use a Fluortec barrier film stopper.

These are the ultimate for long shelf life

west flurotec coated barrier film stoppers

Upgrade your vial containment with FluroTec® Barrier Film Stoppers from West Pharma. Superior design for improved drug packaging and patient safety.

www.westpharma.com

You have to click "In stock" to see the list of available products. The letter on the end designates the color of the cap. 25 vials in a pack.

Best price I could find was here:

ALK Sterile Filling Vials | Sterile Vials | BioPharm World

Shop for the ALK Sterile Filling Vials and other Sterile Vials at BioPharm World

www.biopharmworld.com

Expensive as fuck tho

 

[Photon]

Expensive as fuck tho

Yes lol, really expensive.
Think i'll stick to butyl rubber..

 

[Sampei]

Yes lol, really expensive.
Think i'll stick to butyl rubber..

View attachment 324446

I would just buy the flurotec stopper and cap my own vial with it. A lot cheaper.. need an autoclave tho

 

[Ghoul]

Expensive as fuck tho

Yes lol, really expensive.
Think i'll stick to butyl rubber..

View attachment 324446

I'm seeing $2.80 / vial.

Are you guys looking at something else?

 

[Photon]

I'm seeing $2.80 / vial.

Are you guys looking at something else?

Looks like the pack of 25 is significantly more expensive.
We're looking at the large vials lol

 

[Ghoul]

Looks like the pack of 25 is significantly more expensive.
We're looking at the large vials lol

Yeah I was looking at the 10ml, $70 / 25pk