Some guys notice anxiety from EQ, although imo I blame it mostly on crashed estradiol than something from the compound itself.
But the conversion to e1 instead of e2 maybe has something to do with inducing anxiety and I’m not so sure about that.
Also, EQ depletes gaba and after prolonged use you may need to supplement with gaba, this is another reason of potential anxiety but that’s easy to prevent by supplementing gaba. I take 3-4 times a week 750mg just for the peace of mind.
Another reason NOT to use EQ is if you deal with high RBC and HCT in the first place before adding the EQ. Personally I have a low HCT and despite I want to raise it EQ and other compounds ain’t doing anything. Probably my EPO stimulation is just low.
But having a 50+ HCT and going in a cycle with EQ is like asking for trouble, and not just EQ but high test, deca, primo and other steroids in general.
I don’t think I’ll be using primo again, I have some vials left for just in case but I’m fine with EQ. It’s way cheaper, always available, high concentration and painless in pinning. Primo is a b!tch. Gains are similar with EQ from what I’ve experienced so far but primo comes with a lot of reasons to avoid it.