So here is what i just did. Had high cholesterol in May, LDL was 250 and triglycerides were 250, in July went on 300mgs/wk test from 120. went 11 weeks then started RETA on oct 11, now after 9 weeks my LDL is just about cut in 1/2, came back at 150 and total is 220, so just about under the 200 mark. Last year this time i was 339 total and triglycerides were so high they couldnt measure LDL. They wanted to put me on 2 statins in May and i said F that. RETA is the key, lost 30 lbs in 8 weeks, still holding there at week 9. Gonna stay on reta for another 12 weeks when i do my next blood test.
The GLP and weight loss are terrific. They’ll do a lot for you, but it’s not nearly enough given the damage done before now, not the least of which by LDL 250 and the inflammation factory all that visceral fat was. 125 LDL is continuing the work of narrowing your arteries, just at a slower pace.
If you want to live a long life, and a decent shot of avoiding a heart attack or stroke that leaves you out of breath after 3 steps, drooling and in diapers, or in a coffin, you’d be wise to get a CAC (calcium) score. You’ll have to pay for it yourself, but it can be done for around $150. Mostly as a tool, a wake up call, to motivate you to do what’s necessary by confirming the cardiovascular disease you already have.
After it comes back positive showing just how fucked up your cardiac arteries undoubtedly are, you can use that result to get Repatha, which should be combined with a statin (insist on Pitavastatin as it has the lowest risk of all statins), and ezetimibe. That’ll get your ApoB and LDL down low enough to stop any further plaque buildup (you’ve already got a ton), remove (a little, but it’ll help) some of the fresher plaque, and start stabilizing the rest. Then your risk will slowly back away from the cliff, going down each year as you maintain the weight loss and good lipids.
If you’re lucky all this will start before you develop angina, and none of your vessels are on the threshold of the 90% blockage where noticeable symptoms begin and you’ll have to pencil in some time to get a stent (or 3).