Diluting and Filtering Oils for Female Doses

That's a starting (and maybe final) female TRT does for a WEEK. So you still need to dilute. If you have a woman pin that multiple times a week it'll likely elevate her T much higher than desired.

Mine is diluted - ends up being 4 clicks every day for a total of 14mg/wk. I'm at the gym so I'm too lazy to do the dimensional analysis to walk it back from there but I'm pretty sure that's with a 50mg/ml concentration to start. Not quite awake yet. Awake enough to push plates but not do

I don't think it's possible to accurately measure small doses with syringes.

Diluting the solution gives you greater accuracy with dosing.
Most women on trt use very small insulin syringes. The 30 unit. I found it way more consistent than the insulin pen. Maybe try the trt females group on Reddit for more feedback. I started with the 30 unit. Im only at 1mg test p daily and it was all over the place with the insulin pen until I diluted and went back to the small unit syringe. Try unloading your dose or backfilling into a syringe as a test. I was surprised at the variation. Skin and mood were a mess.
 
Most women on trt use very small insulin syringes. The 30 unit. I found it way more consistent than the insulin pen. Maybe try the trt females group on Reddit for more feedback. I started with the 30 unit. Im only at 1mg test p daily and it was all over the place with the insulin pen until I diluted and went back to the small unit syringe. Try unloading your dose or backfilling into a syringe as a test. I was surprised at the variation. Skin and mood were a mess.
Using a 29G needle head and 250mg/ml testosterone enanthate (MCT/EO) the dose is accurate. Just under 4units on an insulin pin when backloaded.


That's with an Ergo 2 pen. I don't know much about women's hormone replacement but the area under curve for short esters is larger. This means higher peak blood concentrations for a given mg of testosterone. Type2x has a post on it. Generally those kinds of side effects are due to hormone fluctuations. You get higher peak blood concentrations for lower doses.


But I'm not familiar with female physiology. I do know the lowest dose to start women at for FTM treatment with test E is 20mg. So obviously that's the dose at which it starts the virtualisation process more reliably. Generally the shorter esters are used due to their quick clearance from the body in case of side effects, so in this case using test prop for long periods (HRT) doesn't appear to be a good choice.


But as I said I'm not familiar with the topic.


*Backs away slowly*

Look at the pharmokinetics of testosterone enanthate in women (7-10 days is a suitable injection frequency):

1000080227.webp

Sources:
Pharmacokinetics of Testosterone Enanthate
After Intramuscular Injection for Transgender Men
Koji Ichihara,1 Naoya Masumori,1,* Satoshi Fujii,2 and Takaki Toda3
 
Using a 29G needle head and 250mg/ml testosterone enanthate (MCT/EO) the dose is accurate. Just under 4units on an insulin pin when backloaded.


That's with an Ergo 2 pen. I don't know much about women's hormone replacement but the area under curve for short esters is larger. This means higher peak blood concentrations for a given mg of testosterone. Type2x has a post on it. Generally those kinds of side effects are due to hormone fluctuations. You get higher peak blood concentrations for lower doses.


But I'm not familiar with female physiology. I do know the lowest dose to start women at for FTM treatment with test E is 20mg. So obviously that's the dose at which it starts the virtualisation process more reliably. Generally the shorter esters are used due to their quick clearance from the body in case of side effects, so in this case using test prop for long periods (HRT) doesn't appear to be a good choice.


But as I said I'm not familiar with the topic.


*Backs away slowly*

Look at the pharmokinetics of testosterone enanthate in women (7-10 days is a suitable injection frequency):

View attachment 338394

Sources:
Pharmacokinetics of Testosterone Enanthate
After Intramuscular Injection for Transgender Men
Koji Ichihara,1 Naoya Masumori,1,* Satoshi Fujii,2 and Takaki Toda3
Ok so I don’t understand your question then. Its more about the functionality of such a small amount of a viscous substance through the insulin pen. Maybe I misunderstood. I thought you were asking for experience trying this as an option. Or are you suggesting it as an option? Either way been there, done that. This was a functionality question so Im having a hard time understanding the response. After trying every ester my preference is Test P diluted per OP suggestion and delivered using a .3ml insulin syringe.
 
Ok so I don’t understand your question then. Its more about the functionality of such a small amount of a viscous substance through the insulin pen. Maybe I misunderstood. I thought you were asking for experience trying this as an option. Or are you suggesting it as an option? Either way been there, done that. This was a functionality question so Im having a hard time understanding the response. After trying every ester my preference is Test P diluted per OP suggestion and delivered using a .3ml insulin syringe.
I was suggesting using an insulin pen to reliably administer undiluted testosterone enanthate in a weekly shot.

This works because they are medical devices designed to deliver accurately and repeatably a metered dose.

It also works due to the fact that test E takes longer to clear in women so weekly shots are suitable.

I posted the blood levels of women given testosterone enanthate in a single shot to show the longer half life in biological females.

However in order for this to work you need to get a 29G needle head. They are not very common but can be sourced.
 
I was suggesting using an insulin pen to reliably administer undiluted testosterone enanthate in a weekly shot.

This works because they are medical devices designed to deliver accurately and repeatably a metered dose.

It also works due to the fact that test E takes longer to clear in women so weekly shots are suitable.

I posted the blood levels of women given testosterone enanthate in a single shot to show the longer half life in biological females.

However in order for this to work you need to get a 29G needle head. They are not very common but can be sourced.
And I feel like I have done my level best to explain that I tried this and it wasn’t successful with such a small amount of viscous oil since insulin pens are not designed to work with oils. But I will leave you to it.
 
And I feel like I have done my level best to explain that I tried this and it wasn’t successful with such a small amount of viscous oil since insulin pens are not designed to work with oils. But I will leave you to it.
I literally just did this last night

It's not a hypothetical.
 
She's doing 1 mg a day. I don't think an insulin pin has the accuracy for that.
Can you read my previous posts. Weekly dosing is sufficient for test enanthate in women.

Also you can get children's injectors which do half units. They only go to 30 units on the clicker. So even smaller doses can be metered.
 
Can you read my previous posts. Weekly dosing is sufficient for test enanthate in women.

Also you can get children's injectors which do half units. They only go to 30 units on the clicker. So even smaller doses can be metered.
First off- drop the tone. You're speaking like you're the end all authority.
Second- yes, weekly dosing is fine- thats how I dose my lady.
Third- she mentioned daily injections of test P.
Fourth- you're going to have a hard time coping if you don't accept that people do things the way they want, and not the way you tell them.
 
Thanks for the informative thread. Wanted to clarify a bit.

Someone told me yesterday in another thread that extra BA/BB would not be required for this.

Example, I have 200mg/ml Primo, want to cut it in half with MCT to make it 100mg/ml Primo. Can I not just add the MCT and Primo in a vial? Or do I also need to add some BA or BB?
 
First off- drop the tone. You're speaking like you're the end all authority.
Second- yes, weekly dosing is fine- thats how I dose my lady.
Third- she mentioned daily injections of test P.
Fourth- you're going to have a hard time coping if you don't accept that people do things the way they want, and not the way you tell them.
I wasn't aware I had a tone. People can do whatever they want. I was just suggesting an idea that's convenient, simple and accurate.

I also provided relevant sources to help people make an informed decision...

I have stated multiple times that I am not an expert, have no experience with females and HRT.

I am simply sharing the most reliable information I can find on a topic without many resources.
 
He isn’t listening to me. I have tried multiple esters and doses. I found my sweet spot with test P the allows me to maintain a high sex drive, not aromatize, break out or suffer with insomnia. Test C and Test E made me miserable.
I think he just misunderstood the test p part
 
I was replying to the thread in general, not a specific person. Unless I interact with people multiple times I forget who I was talking, what they said etc

I was offering an alternative potential method to diluting testosterone for HRT which introduces multiple vectors of risk.

It took me a bit of searching to find the pharmokinetics of testosterone enanthate and had to resort to looking into FTM therapy.

Due to physiological differences the peak concentrations are higher and the half life is longer.

Anyway each to their own, maybe my posts will help people in the future with similar requirements.
 
Thanks for the informative thread. Wanted to clarify a bit.

Someone told me yesterday in another thread that extra BA/BB would not be required for this.

Example, I have 200mg/ml Primo, want to cut it in half with MCT to make it 100mg/ml Primo. Can I not just add the MCT and Primo in a vial? Or do I also need to add some BA or BB?

Theoretically, you could forego BB/BA, but consider their purpose.

Benzyl Benzoate increases the solubility of the oil. This insures the steroid remains adequately dissolved and doesn’t precipitate out of the solution, maintaining stability. You might get away with lower BB, you’d probably just have to deal with crashed gear more frequently.

Meanwhile, Benzyl Alcohol functions as a preservative and inhibits microbial growth in multidose vials. Self explanatory why you would want this, especially if you don’t plan on shooting up the whole vial in one go. I personally would want to come as close to pharma standards on this one as possible (minimum 0.9%), but it totally depends on your own risk tolerance.
 
Theoretically, you could forego BB/BA, but consider their purpose.

Benzyl Benzoate increases the solubility of the oil. This insures the steroid remains adequately dissolved and doesn’t precipitate out of the solution, maintaining stability. You might get away with lower BB, you’d probably just have to deal with crashed gear more frequently.

Meanwhile, Benzyl Alcohol functions as a preservative and inhibits microbial growth in multidose vials. Self explanatory why you would want this, especially if you don’t plan on shooting up the whole vial in one go. I personally would want to come as close to pharma standards on this one as possible (minimum 0.9%), but it totally depends on your own risk tolerance.
Yeah that makes sense thank you. Might be easier just to cut it (pippy oils that is) with Test then I suppose.
 
I’m writing this dilution guide mostly for women who inject UGL oils whose concentrations are mostly intended for men (whether that’s for TRT or general AAS use). 100mg/mL vials aren’t always available, or our dosages can be less than even 50mg/wk. During my first primo cycle (which was my first oil cycle), I was using a vial of primo200 and injecting roughly 34mg/wk (15 units). At such a low dose, I realized I was losing a lot of oil in the syringe and needle. I also realized that one vial would literally last me for five, 3-month cycles. That’s roughly 2.5 years PER VIAL. For that entire time, I would be sticking that same vial with a 25ga needle, hoping the stopper wouldn’t give out and that the coring particles would be larger than the needle with which I was drawing the oil. I looked in MESO for a dilution guide for women and didn’t find anything concrete. This process is what I was able to piece together over time by going through the brewing thread and paying attention to Ghoul’s filtration Crusade (yaaaaaaay harm reduction). Thanks to all of you who’ve contributed without even knowing I was cyber stalking you for your knowledge. If you have any suggestions, please share.



Materials Needed:
  • Alcohol pads
  • 5 sterile 5mL depyrogenated glass vials (clear glass or amber)
  • Sterile 18 gauge needles and 30 gauge vent needles
  • Sterile 1-10mL leur lock syringes and a 1mL insulin syringe/needle
  • USP grade injection oil (I used MCT)
  • Benzyl Alcohol (1% of the oil volume)
  • Sterile 0.22um PTFE hydrophobic syringe filter (I used 25mm)
  • Gloves (did not use but don’t be like me)


First, calculate your ratios:

For an example, I’m going to use the vial of primo200 I diluted, which tested at 225mg/ml. Let’s assume the vial is 10mL for easier math (though make sure you confirm the actual volume when you draw it into a 10mL syringe. From there, let’s say your dose is 50mg/wk and you want to draw 0.5mL when you inject. Your desired concentration would then be 100mg/mL.

  • 225mg/(100mg/mL) = 2.25mL, so you’ll need 1.25mL of your carrier oil for every 1mL of the finished oil.
  • If we have 10mL finished oil, we need to add 12.5mL sterile carrier oil.
  • The amount of BA needed is 1% carrier oil volume, or 0.125mL.


Second, determine how many vials you want for your new concentration and the calculations per vial:

I personally like to put the equivalent of one cycle per vial to minimize coring as much as possible, which for me was 2mL of original primo200 vial per cycle. Using our example, that would be 5 5mL vials. Note that the actual volume of the vial is significantly greater, so there’s wiggle room (I think my MedLab 5mL vials were closer to 7mL). If we divide the original oil into 5 vials, our calculations per vial will be:

  • 1.25mL x 2 = 2.5mL carrier oil
  • 2ml original primo
  • 0.025mL BA (2.5 units)


Third, draw and filter the primo into the sterile vial:
  • Wipe down and sterilize your work area and all respective vials. Put on gloves (unless you’re me and forget).
  • Warm up your oil vial either in the oven or candle warmer (unless you’re me and also forget, but don’t cause booooy you’ll regret it).
  • Draw the contents of the primo into a 10ml syringe. Detach the needle and attach your filter to the syringe, then a brand new needle to the filter.
  • Put a small vent needle in each sterile vial or you will regret it. It doesn’t need to be larger than a 30ga.
  • Inject 2mL primo into the first vial (yes, the filter eats about 0.7mL primo, but stay with me).
  • Inject 2mL of primo in the remaining 4 vials.
  • Inject the needle/filter combo once more into your first vial and detach the syringe. Your filter at this point still has about 0.7mL primo, while the first vial in which the needle is in has about 1.3mL. You will next push your carrier oil through the filter.


Fourth, add carrier oil:

The MCT oil didn’t go through the filter easily in my large syringe, so I switched to 1mL syringes and that sped up the process. I also didn’t feel like it would be a great idea to warm up the whole bottle of MCT, but maybe I could have. I’ll play around with it next time. I would therefore recommend just using 1mL syringes.

  • Draw MCT oil into a 1mL syringe, detach syringe while leaving the needle in the stopper, attach syringe to the first vial needle/filter combo, and push the oil through. Repeat for all 2.5mL of carrier oil.
  • This first vial will now have 2mL primo, and probably close to 1.8mL carrier oil. We’re going to do the same thing as we did for the primo and move on to the other vials for the time being.
  • Filter 2.5mL of MCT into the remaining 4 vials.
  • Go back to vial #1. You can either now push air through the filter until you get most of the oil out by detaching the syringe, pulling the plunger all the way up, reattaching the syringe, and pushing air through it, or you can line up your vials next to each other and add more MCT into vial #1 until the volume in both vials matches. The second method is probably more accurate because you will never get all the oil out of the filter.


Fifth, add BA:

Draw 12.5 units of BA into an insulin syringe and inject each vial with 2.5 units of BA. Remove vent needles and gently swirl each vial to mix the solution.



Closing Notes:

  • Instead of using 1 0.22um 25mm PTFE filter, you can use 5 13mm filters for each vial to filter in 2ml primo and 2.5mL carrier oil.
  • To prevent coring, I plan to use vial spikes in each vial (another reason I want each vial to last one cycle). The US dom vial spikes are a bit large and don’t have the 5um filter that Altruan has, but you don’t have to pay $27 in shipping from Germany. The only stateside vial spike I’ve found is the McKesson Vial Spike.


Materials Links:

100mg/ ml vial of test p


Let's say you want 1mg testp


Draw 1ml of the test p.

Prep a vial of 9ml pure grapeseed oil..

squirt the 1cc test p into the pure grapeseed vial. stopper cap and seal..

Shake that bitch up for consistency..


Am i retarded?
 
Back
Top