Berberine, the most powerful supplement on the market?

[tubesox]

Claim its comparable to a pharmaceutical drug. Binds to molecular targets in cells. Said to activate the enzyme AMP-activated protein kinase(AMPK) a "metabolic master switch". Used in chinese traditional medicine for years. Also claimed to lower blood sugar, improve heart health and aid in weight loss. Check it out.
https://anabolicminds.com/articles/berberine-the-worlds-most-powerful-supplement-16899/

 

[MindlessWork]

Are there any unbiased studies done on this substance?

 

[TyroneMoreGains]

I think the most powerful supplement available might be Tumeric.
I use it as a spice

But it apparently has something in it called Curcumin that's suppose to be the Shiz niz.

 

[Docd187123]

Activating AMPk will also inhibit lipolysis and at least in fat models, and maybe in humans also but not positive, will down regulate mtor.

Edit* it may also increase hunger

 

[Xlgx]

I read/heard it's a good nutrient partitioning agent with respect to carbs. I have been using it but can not quantify the results.