Tan RS, Cook KR, Reilly WG. High Estrogen in Men After Injectable Testosterone Therapy: The Low T Experience: The Low T Experience.
American Journal of Men’s Health. 2014;9(3):229-234. doi:
10.1177/1557988314539000
Reading this piece of literature could be helpful. In the discussion section of the article, the authors address the debate in the scientific community about high e2 amongst TRT patients. The vast majority of the time, practitioners prescribed AI's
without any signs or symptoms of high e2, they based it solely off of serum blood concentration.
"Based on interviews with select practitioners, we found that the reasons for the high rates of prescribing AI and SERM are partly patient pressure, practitioner confusion, and fear of the harmful effects of high E2 in long term. Some studies have indicated an association of high estrogens to higher rates of heart attacks, strokes, and prostate cancer"
How ever,
"These studies of association do not infer causality and as such should not be used for the basis for treatment of high estrogen."
In my opinion, I would definitely let it ride and rock on. Your estradiol is hardly out of the reference range compared to what we see in this community. Some people even prefer having high e2 compared to normal. Incorporating an AI could very well have a greater negative impact than your elevated e2.
Just my 2 cents.
