A GH and fat loss protocol (rhGH lipolysis) that is science-based

But isn’t the fasted cardio hotspot when it peaks at ~ 2.5hrs post subq? Shorter if IM, maybe 90 mins?
From the "Bolus" book - the peak is 4.5h subq, with a tail lasting up to 12h, which covers waking up time.

Additionally you can check him replying to me on a similar Q in his book thread


Screenshot 2026-02-15 alle 08.12.53.webp
 
Your Bolus book must be different than mine then, as well as your meaning of “2.5” lol
Page 59

> Subcutaneous rhGH administration leads to peak levels at 4 h and a slow decline over the course of the following 12 - 24 h

next page

> Lipolysis and Insulin Resistance Due to FFA Liberation by HSL
RhGH stimulates lipolysis and causes insulin resistance within 1 - 2 h , and these effects disappear after approximately 8 h
[...]
The increase in FFAs is robust and lasts for 1 - 8 h.

The "2.5" referring in the pic is based on the fact that I (also) told him how long it takes to me to get to the gym.
 
Page 59

> Subcutaneous rhGH administration leads to peak levels at 4 h and a slow decline over the course of the following 12 - 24 h

next page

> Lipolysis and Insulin Resistance Due to FFA Liberation by HSL
RhGH stimulates lipolysis and causes insulin resistance within 1 - 2 h , and these effects disappear after approximately 8 h
[...]
The increase in FFAs is robust and lasts for 1 - 8 h.

The "2.5" referring in the pic is based on the fact that I (also) told him how long it takes to me to get to the gym.
His quote:
“Daily exercise:
Morning or daytime bolus ideally 2-3 hr pre-workout
Single large bolus (≥3IU) for lipolysis: [6] showed lipolysis (blood 3-hydroxy-butyrate) was positively correlated to the peak hGH concentration (r=0.65) for the highest dose (6mcg/kg); [40] showed a significant correlation between the peak GH response to exercise and the post-exercise rise in glycerol measured as area under the curve (r= 0.57,p< 0.04). Also, [69] showed that a single s.c. bolus versus two promotes nighttime FFA liberation.

meal post-workout (4-4.5hr post-bolus), see FFA liberation.”

So the fasted cardio @ around 2.5hrs after pin, then eat at around 4.5-5hr post pin. Will post/paste any relevant detail from the book if needed.
 
His quote:
“Daily exercise:
Morning or daytime bolus ideally 2-3 hr pre-workout
Single large bolus (≥3IU) for lipolysis: [6] showed lipolysis (blood 3-hydroxy-butyrate) was positively correlated to the peak hGH concentration (r=0.65) for the highest dose (6mcg/kg); [40] showed a significant correlation between the peak GH response to exercise and the post-exercise rise in glycerol measured as area under the curve (r= 0.57,p< 0.04). Also, [69] showed that a single s.c. bolus versus two promotes nighttime FFA liberation.

meal post-workout (4-4.5hr post-bolus), see FFA liberation.”

So the fasted cardio @ around 2.5hrs after pin, then eat at around 4.5-5hr post pin. Will post/paste any relevant detail from the book if needed.
Does timing really take that big of a roll? Genuine question as im trying to lear
 
So ive been doing 4iu pre gym. First thing in am. 4iu pre bed. Leave it or is there better protocol for cutting
I’d think the triple lipolysis surge daily would be the most important part there for you really, you’ll be good assuming insulin sensitivity stays good…but if you can make one of the pins happen 2.5 hrs before a workout of any kind, have at it, you’re winning some extra fat loss
 
Thank you all for all the information. I will move my injection to 4:30 pm (previously in the morning) due to this thread in order to hit the 7 pm training.
 

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