Fluoroquinolone

Cubbie it sounds like you have a very sensitive immune system.

Oh - talking about the anaphylactic reaction - yes, perhaps, but it is a side effect common enough to cause it to get pulled off of the market elsewhere. It has something to do with it's similarity to heparin I believe...I don't quite recall though.
 
Yes I talked to a few lifters that had same issue with the tendons and it matches my symptoms completely. They did injections of chicken cartliege guided by ultra sound deep in the joint and they where fine in 8 weeks. It does not hurt just annoying when I lift. I might try some DMSO on it to see if I can reduce inflammation. I used DMSO back in the day on my shoulders and cleared it up in matter of a few days.

Chicken cartilage? Are you talking about adequan or legend or something similar? I've heard a few success stories but a lot of failures as well. I tried it and it caused a minor anaphylactic reaction...which is why it was taken off of the human market in Europe.

HAN might be referring to Synvisc injections which are made via chicken comb extractions, or something else entirely that I have no idea what he is talkinga bout.
 
cubbieblue, can u still lift heavy? and squat/deadlift high weights?

Right now kind of. I definitely am oddly sore the next day if I attempt to go heavy. I feel much more comfortable doing crossfit type workouts with reasonable weights. For example, yesterday I did a lot of front squats and both of my wrists feel painful today from the strain on them.
 
A recent revelation for me . . .

Swimming is possible.

It's the first exercise I've been able to do since my Jan 14 floxing. I never would have guessed it was possible, especially given my wrist, but I was pleasantly surprised and have been at it a few times / week since having first given it a go over Jul 4.

For anyone affected that's taking it hard that exercise is no longer possible . . . try it.

Any word from your MRI, Cubbie? I had one done on my right wrist (which is still completely incapacitated) back in Feb . . . everything normal, of course.
 
A recent revelation for me . . .

Swimming is possible.

It's the first exercise I've been able to do since my Jan 14 floxing. I never would have guessed it was possible, especially given my wrist, but I was pleasantly surprised and have been at it a few times / week since having first given it a go over Jul 4.

For anyone affected that's taking it hard that exercise is no longer possible . . . try it.

Any word from your MRI, Cubbie? I had one done on my right wrist (which is still completely incapacitated) back in Feb . . . everything normal, of course.

Haven't seen the pysiatrist yet. I had the appt. yesterday but I had to reschedule. I'm really looking for arthritis in my knees, and tendon damage in my shoulders. I bet she won't find much, but worth a look.

Karter, how are you doing otherwise? Do you think you will see a full or partial recovery...or do you think you are going to end up a long timer?
 
Quinolones are prescribed for urinary tract infections and prostate because they're concentrated in urine
consult your doctor to use another urinary antiseptic like nitrofurantoin to avoid these complication
 
Quinolones are prescribed for urinary tract infections and prostate because they're concentrated in urine
consult your doctor to use another urinary antiseptic like nitrofurantoin to avoid these complication

I can't tell if you are a dedicated spammer, super intelligent robot, or really weird person.

Fess up, which one is it?
 
CubbieBlue,

Your posts have been very informative, i was floxed in early MAR 2011 (Cipro 500 mg 2x per day for 3 days), I am glad i found this thread. I would consider my reaction very similar to yours, as most of my severe problems have not developed until months later, almost all of them are purely felt on the physical level, it appears that the mental issues (insomnia, anxiety, emotional instability) have abated. Currently only my shoulders and feet hurt, although my calf muscles were strained immediately after consumption, that went away around month 3 and was replaced by pain in my feet.

It is amazing how people of any physical/environmental/genetic/scoail background can be impacted by these quinolones, it is hard to find a common thread that would clue us into what is happening. This is way beyond simple fluoride poisoning, something is happening in our bodies.

Have you made any progress since last posts, i am supplementing, but admittedly in a blind way, I have no idea how to proceed.

All I know is i need to stay positive and hear about people getting better.

Thanks.
 
Cubbie, are you still taking the ghrp's? If so, did they help?

Yes I am.

Honestly I've been using it off and on since I suffered my adverse reaction so I can't really determine whether they helped or not. I will say that while my reaction started off very severe I have experienced one of the quickest recoveries from an "intermediate" reaction that I have come across.

At ~8 months out I can lift weights, stretch, jog a bit, play some rugby, etc. I still suffer diffuse tendonitis (particularly bad in my knees, left achilles, wrists), floaters, and some other minor issues. I anticipate that within the next year I will reach a 90-100% physical recovery. The other stuff may stay, it might not. I will keep using the peptides probably off and on the rest of my life (or until more evidence on long term GH use comes out) to help reverse the fallout from this shit.

I just had some musculoskeletal ultrasound and found out that my tendons are all enlarged or swollen. THis is the source of my crepitus. I am wondering if there is a way to reverse this swelling without NSAIDs...as NSAIDs eventually make the pain worse for me.
 
@ cubbieblue

How long did you take cipro and the others in total?
I read about this on another forum in the past and a doctor there said that cipro is not an issue
unless you take it over many weeks. Is this not true?
I think it's crazy that so many doctors are quick to prescribe them. Why do they not switch
to something else? Or is there nothing else you could take against prostate or urinary tract
infections? :confused:

And how can one as a patient find out wether an antibiotic drug belongs to the group of
those dangerous antibiotics or not? I only know that cipro is dangerous but I don't know the
names of all antibiotics which contain this stuff.

And is there anything you can take to improve the tendons or is the damage permanently?
I heard that a professional athlete for example would never get cipro from his doc because of the dangers.
 
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How long did you take cipro and the others in total?

3 days of levaquin
3 months later
5 days of cipro

I read about this on another forum in the past and a doctor there said that cipro is not an issue
unless you take it over many weeks. Is this not true?
not true

I think it's crazy that so many doctors are quick to prescribe them. Why do they not switch
to something else? Or is there nothing else you could take against prostate or urinary tract
infections? :confused:
pharm reps have brainwashed them into thinking that if you want prostate absorption you have to use a quinolone

And how can one as a patient find out wether an antibiotic drug belongs to the group of
those dangerous antibiotics or not?
research your medication...if it's a quinolone ask for an alternative

And is there anything you can take to improve the tendons or is the damage permanently?
Wish I knew.

I heard that a professional athlete for example would never get cipro from his doc because of the dangers.
Yeah, probably not.
 
This sucks. I did not know that only 5 days could have such an effect. This is crazy.

I also thought if you get side effects you'd notice them immediately. Does this mean if you've
taken cipro a few years ago then you could still get side effects or already have tendon damage without noticing it?

And does this stuff also contain fluoride because of the name "fluoro"? :eek:
I heard that fluoride can permanently damage a small area of the brain where it builds up and then the person is basically never the same. I'm not sure how true that is but I think the doctor who made this statement had researched fluoride.
 
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I also thought if you get side effects you'd notice them immediately. Does this mean if you've
taken cipro a few years ago then you could still get side effects or already have tendon damage without noticing i
t?



I have talked to and personally met individuals that have had 10 month + delayed reactions. These are normal people. Not whackjobs.
 
Yes I am.

Honestly I've been using it off and on since I suffered my adverse reaction so I can't really determine whether they helped or not. I will say that while my reaction started off very severe I have experienced one of the quickest recoveries from an "intermediate" reaction that I have come across.

At ~8 months out I can lift weights, stretch, jog a bit, play some rugby, etc. I still suffer diffuse tendonitis (particularly bad in my knees, left achilles, wrists), floaters, and some other minor issues. I anticipate that within the next year I will reach a 90-100% physical recovery. The other stuff may stay, it might not. I will keep using the peptides probably off and on the rest of my life (or until more evidence on long term GH use comes out) to help reverse the fallout from this shit.

I just had some musculoskeletal ultrasound and found out that my tendons are all enlarged or swollen. THis is the source of my crepitus. I am wondering if there is a way to reverse this swelling without NSAIDs...as NSAIDs eventually make the pain worse for me.

Nothing reduces inflammation like glucorticoids.
How so with the pain and NSAIDS?
 
Nothing reduces inflammation like glucorticoids.
How so with the pain and NSAIDS?

Glucocorticoids are also horrible for tendons and ligaments.

http://www.allvoices.com/contributed-news/7139487-cortisone-injections-prolong-tendon-problems
http://isakos.omnibooksonline.com/2011/data/papers/eposters/2209.pdf
Glucocorticoids inhibit tenocyte proliferation and Tendon progenitor cell recruitment - Scutt - 2005 - Journal of Orthopaedic Research - Wiley Online Library

NSAIDs are also contraindicated for chronic (I would actually argue should actually be ALL) tendon and ligament issues.

If I pop an etodolac the pain is diminished for about 8-12 hours. Afterwords the pain is about 2x worse than it was before I took it. Especially if I do anything active. It's weird, but I've heard a few people with tendinopathy give similar reports. i think it has to do with the NSAIDs killing the inflammatory response completely, and thus initially killing the pain. Then you go and work the tendon and whatever normal healing response the tendon usually undergoes from all of the tiny bits of damage it undergoes from normal use doesn't happen because you've killed the inflammatory response off maybe 90% (for example). That's why you get the delayed pain.
 
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