MESO-Rx
Anabolic Steroids
Deca Dosing
- Thread starter JG91
- Start date
Mfras
Member
I thought the way to bone mass was weight loading and tension forcing adaptation. Be like Conan and push the wheel. And drink your milk.
But what do I know I only have an 8.2lb skeleton?
But what do I know I only have an 8.2lb skeleton?
Astartes
Member
You aren’t going to get a right answer.
Deca (Nandrolone) is a compound that impacts people with a particularly wide range of sides.
Folks like myself get very little mental and negative physical sides from 19-Nor, others get immediate sides from low doses.
You literally need to dial in your balance. You won’t get to this without trial and error
tweek
Member
Yup exactly the same dose im on right now. 2:1 ratio has always worked for me
Ya I figured that before starting this thread. But I asked because there weren’t a ton of clearly asked threads on this topic when I used search
Why insuline on just 2iu hGH, is your Glucose reading that bad without it ?
Just stared it.
If glucose is bad can’t you low dose GLP instead of insulin? Obviously it’s much safer, not sure about how effective it is though.
BALLISTIC
Member
If you browse some of the Reta threads you'll see it's mixed opinion. In my case no BG control occurred until 6mg and up to 11mg. Some state Tirz is doing more for this. I don't have experience with Tirz. Sema years ago did absolutely morning but cause nausea.
So I'm not confident in low dose, but others have stated it worked. Others stated it elevated theirs.
shredded.lyfe
Member
I'm confident all the low dose schmucks are all placebo and feels bros
Wtf do you mean you get hunger suppression on 2mg a week reta lol, absolute horse shit
BALLISTIC
Member
Yeah dude I don't know what they're on. Reta has studies showing scientific data, so I agree with you wholely.
Placebo is strong though in its own right. They use it for opioid addicts frequently. Mind over matter.
For me Reta hit at 6mg minimal, at 11mg it's solid gold. I'm on a reliable source 55mg vials, this works perfect. I get 5 weeks per vial.
I try not to get into the feels like these dudes. I actually evaluate what is going on with my body based off the clinical data. The data shows the glucose effects tend to come first, and the appetite suppression layers in as central signaling ramps up.
With retatrutide, glucose control and insulin sensitivity usually improve first. Appetite suppression comes a bit later as the brain signaling builds. It’s not a switch more like layers turning on.
Again the science shows this so yeah in a way stfu. Haha
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adrenalytic
Member
My anecdotal experience. I first used reta in Nov. 2024. It was my first time using a GLP-1 as well. I started at 2 mg. I felt nothing. The next week came around and took another 2 mg and bam. Instantly could not eat. I was able to ride this dose for 2 months (I eventually moved up to 4 mg) and lost 45 lbs. over 3 months of hard dieting and cardio. It was difficult to eat over 2500 kcals/day on that low dose. This was not placebo, my stomach simply would not accept more food. I get that same what I describe as a "brick in your stomach" feeling now at higher doses but it is not nearly as pronounced.
I attribute my response to being a GLP-1 virgin because now I only get moderate suppression at 5 mg/wk (haven't needed to go higher yet) even after desensitizing.
Basically, we're all different.
Mfras
Member
I was fat my whole life and I just don’t understand why everybody talks about GLPs like they’re magic. If it’s a soccer mom who just can’t stop going to drive throughs every day then sure it totally makes sense. But for a bodybuilder or someone living the BB lifestyle aren’t we all either eating basically the same stuff every day and or counting calories?
I’m on 4mg reta for the metabolic/insulin effects- it was hard to eat for like a week then back to normal.
The newer phone calorie counting apps and a cheap digital kitchen scale make working the CICO numbers so easy and fat loss comes for me comes from eating in a deficit and keeping training consistent.
Are most people just eating when they’re hungry and not doing a meal plan? I’m not better than anybody else- just confused because I lost like 120lbs and didn’t put reta in until the last 20 and it’s a nice background compound for me not a primary driver.
I’m on 4mg reta for the metabolic/insulin effects- it was hard to eat for like a week then back to normal.
The newer phone calorie counting apps and a cheap digital kitchen scale make working the CICO numbers so easy and fat loss comes for me comes from eating in a deficit and keeping training consistent.
Are most people just eating when they’re hungry and not doing a meal plan? I’m not better than anybody else- just confused because I lost like 120lbs and didn’t put reta in until the last 20 and it’s a nice background compound for me not a primary driver.
adrenalytic
Member
When you get sub 10%, the suffering is real. Your body does not like being this starved. GLP-1s take the suffering out or at least blunt it to a less noticeable degree.
Mfras
Member
That totally makes sense.
shredded.lyfe
Member
Maybe their hunger levels are absolutely fucked because they've raped themselves into insulin resistance without realising and as we know insulin sensitivity and glucagon activation can provide satiety on their own without the glp1 component.
Reta won't really start making an impact on glucagon until about 8mg but that doesn't mean their natty glucagon activity isn't working in the background with the all of a sudden increased insulin sensitivity.
Atleast thats my theory as to how they're getting a huge response from such low doses.
For those of us without fucked up insulin from pounding sugars and growth hormone for years, reta won't really do much until the latter doses.
Listening to anyone tell someone hoe they will feel in glps or any drug for that matter os nutz. Sure we can tell people our experiences or the average of what people say but we certainly can never say 2mg or 5mg of reta doesn't cause food suppression..
Thats just ramped up nonsense
Thats just ramped up nonsense
BALLISTIC
Member
Yes we actually can because unlike BS peptides floating around the data is scientifically based. It's being thoroughly researched in clinical trials where plenty of collective research is showing factual information. Again we also carefully used the term PLACEBO, which in itself is a powerful mechanism of mind fuckery, but doesn't uphold long-term. See below...
Single-ascending dose (healthy participants): fasting glucagon drops only at the very top doses tested (4.5–6 mg) starting abrupt.
In the phase 1 single-dose study, the reported signal was that mean fasting glucagon decreased after the two highest single doses:
4.5 mg and 6.0 mg: decreased from ~24 hours post-dose to day 15 �
ScienceDirect +1
What that means: in the single-shot setting (not chronic titration), the clearest fasting-glucagon decrease was seen only at 4.5–6 mg. �
ScienceDirect +1
Putting it together: dose thresholds you can actually defend from human data
Best-supported “primary effect” thresholds (by endpoint):
Post-glucose challenge glucagon (AUC) suppression (12-week data, T2D): starts at ~1.5 mg, stronger at 3 mg+ / titrated higher over minimal 12-week span.�
SIO Società Italiana Obesità
Fasting glucagon reduction (single-dose data, healthy): most clearly reported at 4.5–6 mg single dose. �
ScienceDirect +1
“Absolutely not effective” at lower dosing.
No effective at a lower dose?
So how is it example the guy above takes 2 to 4mg and gor 1 week felt no hunger issue.
While sure its 1 person but I've never in my life taken reta over 5mg and I lost over 100lbs in 1.3 years. (Not the whole time on reta.
So not badgering your post at all more trying to understand how it makes total sense group everyone into feel the same way
