The Lobster International, AU, CANADA and EU Domestic HGH, PEPTIDES and Turkish Pharmacy

“Ghoul, let’s apply a forensic level of precision to this particular strand of your argument—the notion that zinc-induced “strings” in a UGL rhGH vial represent amyloid fibrils capable of seeding beta-amyloid (Aβ) plaques, thereby precipitating Wrangel7’s symptoms into an Alzheimer’s trajectory. You’ve leaned heavily on that 2016 Scientific Reports paper to imply a mechanistic bridge, but a closer examination reveals this as a categorical error, not a causal chain. We’ll unpack it systematically, because conflating growth hormone (GH) fibrils with Aβ is like equating a firecracker to a thermonuclear device: superficial similarities in “explosive” potential, but worlds apart in structure, function, and consequence.


First, the identity crisis: Those zinc-facilitated structures in the study are unequivocally GH-specific fibrils, not Aβ. The paper describes them as short, curved aggregates (10–20 nm in length, per TEM imaging) formed via zinc’s coordination with GH’s histidine residues, stabilizing a dimeric or oligomeric state akin to natural pituitary storage granules. This is physiological amyloidogenesis—a benign, reversible process that enhances GH bioavailability, as corroborated in a 2022 Endocrinology review on hormone packaging. Aβ, by contrast, is a 39–42 amino acid peptide cleaved from amyloid precursor protein (APP), forming long, straight beta-sheet fibrils (hundreds of nm) that template neurotoxic plaques via prion-like templating. Sequence homology? Negligible—GH is a 191-residue helical protein; Aβ is a beta-strand fragment. No cross-seeding documented: a 2023 Journal of Alzheimer’s Disease meta-analysis on heterologous amyloids (e.g., alpha-synuclein influencing Aβ) finds no GH-Aβ interactions, let alone propagation. Your “amyloid-like” label? A semantic sleight-of-hand; not all amyloids are pathogenic, Ghoul—insulin forms them too, yet diabetics aren’t seeding plaques from their pens.


Second, the seeding fallacy: Even granting your fibrils’ existence post-reconstitution (dubious, given plasma denaturation), there’s no pathway for them to emulate Aβ’s plaque-seeding. True Aβ seeding requires conformational templating—exogenous Aβ misfolds endogenous Aβ into beta-sheets, per 2024 cryo-EM studies in Nature Structural & Molecular Biology. GH fibrils? They lack Aβ’s sticky hydrophobic core (e.g., residues 16–20 in Aβ); instead, they rely on zinc bridges that dissolve in vivo. Animal models underscore this: intracerebral Aβ injections seed plaques in APP-transgenic mice (e.g., 2025 Acta Neuropathologica Communications update), but no analogous GH experiments exist—because GH isn’t implicated in amyloid cascades. Peripheral injection? As we’ve established, it fails for Aβ absent heroic doses; for GH, it’s a non-starter. A 2024 Frontiers in Neuroscience paper on iatrogenic amyloidoses explicitly excludes recombinant proteins like rhGH, noting their monomeric purity precludes seeding. If GH fibrils seeded Aβ, we’d see signals in the 40-year rhGH pharmacovigilance data—yet FDA’s FAERS database (queried through 2025) reports zero AD linkages, versus the c-hGH outliers you cherry-pick.


Third, the temporal and symptomatic mismatch: Wrangel7’s acute fog and headaches align with GH’s direct effects—e.g., IGF-1-mediated cerebral edema or glucose swings, per 2023 Clinical Endocrinology cohorts on acromegaly analogs—not insidious plaque buildup, which incubates asymptomatically for decades (e.g., 20–30 years pre-diagnosis in AD trials). Your neuroPASC angle? Valid for BBB vulnerability, but it amplifies inflammation, not fibril smuggling. No 2024–2025 studies (PubMed-scoured) link rhGH to AD exacerbation; if anything, low-dose rhGH shows neuroprotective promise in mild cognitive impairment trials (Journal of Clinical Endocrinology & Metabolism, 2024), boosting hippocampal neurogenesis without amyloid risks.


Ghoul, your filtration advocacy stands on firmer ground—UGL impurities warrant it—but draping it in this Aβ doomsaying erodes credibility. Wrangel7’s plight merits pragmatic advice: taper the 8–14 IU, monitor IGF-1, rule out confounders via that MRI. By inflating GH fibrils into Aβ proxies, you’re not illuminating; you’re obfuscating, turning a solvable side effect into a speculative scourge. Evidence demands distinction, not conflation. Retract the amyloid alarm, refocus on facts, and perhaps Wrangel7 sharpens without the shadow of your specter. Logic, after all, is the ultimate filter.”

I’m prepared for being roasted for the AI slop, but it basically hit all the marks.
Looking forward to the great @Ghoul's response haha
 
You should be able to get it with one whack if you pay for the service lol
I don't pay for it. Usually would take me at least 5 or 6 to arrive at something like this, still the information is always off when you take a closer look.

The other day I asked chat gpt about turning test base raws into test cyp raws.

later I notice the instructions said to put

"Approx. 50 liters of N,N-dimethylacetamide (DMA)"

into


"Large reaction vessel (10-15 liters capacity)"
 
I don't pay for it. Usually would take me at least 5 or 6 to arrive at something like this, still the information is always off when you take a closer look.

The other day I asked chat gpt about turning test base raws into test cyp raws.

later I notice the instructions said to put

"Approx. 50 liters of N,N-dimethylacetamide (DMA)"

into


"Large reaction vessel (10-15 liters capacity)"
And yet there's still people complaining about AI not answering medical questions geez ;)
 
How many prompts did this take?
Good eh? I told it to use the style of Ben Shapiro to own with facts and logic :) (I’m being ironic here) .

But seriously Ghoul has a bad habit of stretching the truth either intentionally or because he has made himself believe it, in order to induce fear in others in a sadistic manner. It’s not the first time.

He’s also been found completely making up things to support this end.

E.g pretending he had a friend with a access to an NMR lab test UGL tirzepatide and show it had improper structure.
 
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I just asked Deep AI to argue against @Sera for @Ghoul and it denied, and said it would not spread false information. This was the response.

"The fundamental flaw in your argument is the conflation of zinc-induced GH fibrils with amyloid-beta (Aβ) plaques, despite clear biochemical, structural, and pathogenic differences. You rely on superficial similarities and misinterpret the 2016 study to suggest that GH fibrils can seed or mimic Aβ aggregation, but the evidence shows they are distinct entities—GH fibrils are benign, reversible hormone storage structures, not pathogenic amyloids capable of templating neurotoxic plaques. Moreover, the absence of experimental data, epidemiological links, or mechanistic pathways connecting GH fibrils to Alzheimer’s pathology invalidates your extrapolation. This conflation confuses correlation with causation and undermines the scientific validity of your assertion."

tenor-2342508748.gif
 
E.g pretending he had a friend with a access to an NMR lab test UGL tirzepatide and show it had improper structure.
I recall this, that there was no way a ugl could replicate the original tirzepitide from eli lilly because it was too complicated and that it was going to cost some extraordinary amount of money. What was the result?
 
I recall this, that there was no way a ugl could replicate the original tirzepitide from eli lilly because it was too complicated and that it was going to cost some extraordinary amount of money. What was the result?
There was no result, as the test was never done. He just made up a lie for some bizarre reason.

But it just goes to show what kind of person you are dealing with here.

Yes a useful contributor, but also a twisted person.

Hiccup Hell
 
If I am remembering correctly the original nuked thread was saying something about the cost being upwards of 10,000usd?
There's much more going on in regards to potency and half life than peptide purity tests indicate.

It sounds like you got an exceptionally strong batch compared to what you had previously. Or maybe just fucked up in a way that caused stronger receptor binding to something inducing hiccups.

I had a conversation with a pharmaceutical scientist, and he was able to connect me with a lab that had a look at a leftover vial of QSC 30mg group buy Tirz that had tested at around 98% purity, yet 20mg doses I had been taking for months (which did work) were clearly not as strong as 15mg pharma.

Despite the dismissal of "feels", it became obvious after going back to 15mg pharma pens. While I was expecting a lessening of effect, it was so strong I ate too much for the dose, and ended up getting severe sides. The duration of appetite suppression was clearly longer than the QSC Tirz as well.

TLDR, I had a battery of tests done on that vial, which, despite a huge discount still cost $1400.

HPLC-MS showed this year old vial at ~96%+ "purity", but an NMR analysis, which I never heard of before, revealed two major problems.

One was that an expensive, hard to get ingredient in Tirz was substituted in the QSC Tirz for a cheap cosmetic ingredient, and the second was a "lipid linker" attached to the wrong part of the peptide. Doing it this way likely cut the time to manufacture the Tirz in half.

Neither is these is detectable by an HPLC-MS "purity" analysis, and among other (some potentially health harming) issues, can reduce potency and duration.

This might explain why batches of GLPs, rHGH, and other peptides can seemingly vary so much in potency despite appearing in HPLC-MS to have similar purity and dosing.
This was clearly fantasy, there was no proof of any of these tests. Also the things he is claiming don’t make any logical sense.
 
Hi @TheLobster. Looking to order soon to UK.

From reading the thread it seems like you ship to your own UK location first then forward on? Having been in legal trouble before, that's an ideal situation for me. If that is the case, which warehouse do I order from?

Sorry for questions that are probably obvious to everyone else!
 
EU domestic stock is back.

All warehouses are operating except the international warehouse.

EU domestic stock is limited.

The international warehouse will open in January.

Thank you
all international warehouse including "pharma grade and pct" international close till january?
 
See u in Janurary

rock family GIF
 

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