A cry for help - Extreme pip after using test propionate 200mg/ml

[rxzed]

Not to wisest compound choice. Reminds me when I thought I was really smart for going with 400mg/ml test.

Not true. Shutdown happens within days, even after the first injection. He might bounce back fast though.

The HPTA axis isn't an off/on switch. If this were true your FSH/LH would immediately rebound when discontinuing use. It is a gradual change that happens over months.

Edit: I should say weeks, months is a little generous. Nonetheless, 1 week of short ester test won't cause any noticeable side effects.

 

[juicebro]

The HPTA axis isn't an off/on switch. If this were true your FSH/LH would immediately rebound when discontinuing use. It is a gradual change that happens over months.

Edit: I should say weeks, months is a little generous. Nonetheless, 1 week of short ester test won't cause any noticeable side effects.

I didn't say it was an on and off switch. OP is probably fine. But the fact is there is significant suppression after a single injection.

I'm too lazy to dig up the research myself but I know it's well documented.

What the studies show after a single injection​

1) Testosterone enanthate 100 mg or 200 mg, single IM injection​

A classic Fertility & Sterility study measuring serial hormones after one injection reports rapid gonadotropin drops:

• Quote: “Serum LH and FSH fell rapidly… The first decrement occurred between days 1 and 2 (−39 ± 6% for LH and −28 ± 9% for FSH).”

PubMed: Comparison of the kinetics of injectable testosterone in eugonadal and hypogonadal men - PubMed

2) Testosterone enanthate single-dose study showing larger suppression by day 4​

Healthy volunteers given one IM dose of testosterone enanthate had large LH and FSH suppression by day 4, even at a dose that is not extreme:

• Quote: “S-LH and s-FSH were significantly decreased… on Days 4 and 14.”
• Quote with numbers (single dose 125 mg): “After the 125 mg dose, LH decreased by 65%… and… FSH 45%” (Day 4).
• Quote with numbers (single dose 500 mg): “73% and 92% decrease in LH on Days 4 and 14” after 500 mg.

Full text: Effects of different doses of testosterone on gonadotropins, 25-hydrox | SAR

3) Testosterone cypionate: LH suppression after the first injection​

Another Fertility & Sterility paper (testosterone cypionate) states suppression occurs even with the first injection:

• Quote: “Luteinizing hormone became suppressed in men receiving their first intramuscular TC injection…”

PubMed: Hormone kinetics after intramuscular testosterone cypionate - PubMed

What this means in plain terms​

• After one injection, it is normal to see roughly 25% to 65% LH suppression within the first few days depending on dose and design, with some studies showing larger suppression by day 4.
• That is “shutdown” in the only sense that matters physiologically: the brain-pituitary signal (LH/FSH) drops, so testicular endogenous production drops.

 

[rxzed]

I didn't say it was an on and off switch. OP is probably fine. But the fact is there is significant suppression after a single injection.

I'm too lazy to dig up the research myself but I know it's well documented.

Fair enough, I'll read up on it more. Most of the research is on hypogondal men that already have weak LH secretion, but I stand corrected.

 

[Burly]

Genuine pharma prop intended for medicinal use is 50mg/ml. Given its half-life, it makes no sense for it to be made higher than that for TRT.

 

[Zebedee]

That’s clearly aimed at the US TRT++ market as a legal PED & not what I would consider proper pharma product, particularly as it’s a compounding pharmacy chain.

Other than the Indian “for export only” etc products (ie the PED black market), you won’t find pharma 100mg/ml test prop because there’s no legitimate medical use for it & thus it’s not approved for use by medicine licensing agencies akin to the US FDA.

 

[Vitamin T]

Complete newbie here, started my first cycle 4 days ago. Have been doing everyday injections 0.2 ml which is 40 mg of Test prop 200mg/ml vial. First few hours it does not hurt at all but the next day, it feels as if someone stabbed me or shot me with a gun in that muscle. How do I deal with this pip? Is it common?

Test prop @ 200mg/ml is a pretty high concentration. That’s probably why you’re getting crippling PIP.

It won’t help that you have virgin muscle as you’re a newbie to injecting gear, but I’d put it down to the high concentration.

 

[SeriosReborn]

Test prop @ 200mg/ml is a pretty high concentration. That’s probably why you’re getting crippling PIP.

It won’t help that you have virgin muscle as you’re a newbie to injecting gear, but I’d put it down to the high concentration.

Can be combination of both. Virgin muscles + high concentration = disaster

 

[Vitamin T]

Can be combination of both. Virgin muscles + high concentration = disaster

Exactly! Couple that with poor injection technique too, & you’re walking like a 3 legged horse.

 

[Burly]

Warm up your gear to BT and inject slowly can also help, but the dose per ml won’t help much. More people also have PiP from Pharma Grade sust by the prop ester, whats just 30mg/ml. So the ester prop alone can give you PiP as well in peanut oil.