Hgh contacting bubbles - normal ?

[ddweeeeeee]

I had reconstituted my gh from a new source today and seemed to be a lot of foam and bubbles at first , the hgh seemed to settle after 20 mins but still containes some bubbles as shown in the photos - is this normal ? Does it indicate contamination !

 

[Dial It In]

I had reconstituted my gh from a new source today and seemed to be a lot of foam and bubbles at first , the hgh seemed to settle after 20 mins but still containes some bubbles as shown in the photos - is this normal ? Does it indicate contamination !

Should be good and settle. Looks like air bubbles. If your BAC is room temp and gh is cold it can happen more than when they are the same temp. Everyone has different preferences. Make sure to tilt your bottle and get the pin on the side of the vial when adding bac and control the speed of how fast the bac is being pulled into the vial. Just let it sit in the fridge after you add the bac for a bit

 

[CorgisOnTren]

Normal

 

[Andrewjo]

That seems pretty regular to me

 

[juice87]

Normal. I find letting the vacuum out does it faster

 

[Ateam2023]

I had reconstituted my gh from a new source today and seemed to be a lot of foam and bubbles at first , the hgh seemed to settle after 20 mins but still containes some bubbles as shown in the photos - is this normal ? Does it indicate contamination !

It indicates you don't know how to reconstitute HGH, try angling your needle towards the side of the vile and let the water run down into the puck and let the vacuum do the work for you.

 

[ddweeeeeee]

Should be good and settle. Looks like air bubbles. If your BAC is room temp and gh is cold it can happen more than when they are the same temp. Everyone has different preferences. Make sure to tilt your bottle and get the pin on the side of the vial when adding bac and control the speed of how fast the bac is being pulled into the vial. Just let it sit in the fridge after you add the bac for a bit

I was concerned thinking bacteria releases co2 in the form of bubbling and fizzing and with hgh I previously used it had never been that fizzy and bubbly for so long ,

 

[Ghoul]

I was concerned thinking bacteria releases co2 in the form of bubbling and fizzing and with hgh I previously used it had never been that fizzy and bubbly for so long ,

Generating bubbles / foam is mostly reconstitution technique, but if they’re stable, not clearing up within 30 minutes, it’s a sign of poor formulation (excipient ingredients, ie “filler”) and/or the presence of damaged (unfolded aka denatured) rHGH.

The rHGH monomers (individual functional molecules) present in the bubble “walls” unfolds and oxidizes. This is a well known, proven in many experiments, path of rHGH degradation. It’s why commercial rHGH often contains a surfactant ingredient. To prevent this from happening. The most common is Poloxamer 188. UGLs know this type of degradation doesn’t show up in the tests we use, so they don’t bother. (Just like dimer was high until it started being tested, and they started making sure to minimize it).

Also, using less than 1ml per 15iu can make this problem worse.

 

[ddweeeeeee]

Generating bubbles / foam is mostly reconstitution technique, but it they’re stable, not clearing up within 30 minutes, it’s a sign of poor formulation (excipient ingredients, ie “filler”) and/or the presence of damaged (unfolded aka denatured) rHGH.

The rHGH monomers (individual functional molecules) present in the bubble “walls” unfolds and oxidizes. This is a well known, proven in many experiments, path of rHGH degradation. It’s why commercial rHGH often contains a surfactant ingredient. To prevent this from happening.

dam you replied I tried to somehow message you but idk how it works on here

Anyways - I do agree there might be poor formulation as it isn’t a great source however would the hgh still be usable considering it is , and by clear up do u mean the bubbles completely go away , and what would it mean if it didn’t completely go away ? Still usable ?

 

[ddweeeeeee]

Generating bubbles / foam is mostly reconstitution technique, but if they’re stable, not clearing up within 30 minutes, it’s a sign of poor formulation (excipient ingredients, ie “filler”) and/or the presence of damaged (unfolded aka denatured) rHGH.

The rHGH monomers (individual functional molecules) present in the bubble “walls” unfolds and oxidizes. This is a well known, proven in many experiments, path of rHGH degradation. It’s why commercial rHGH often contains a surfactant ingredient. To prevent this from happening. The most common is Poloxamer 188. UGLs know this type of degradation doesn’t show up in the tests we use, so they don’t bother. (Just like dimer was high until it started being tested, and they started making sure to minimize it).

Also, using less than 1ml per 15iu can make this problem worse.

And btw I used 1mL for 15iu

 

[Ghoul]

dam you replied I tried to somehow message you but idk how it works on here

Anyways - I do agree there might be poor formulation as it isn’t a great source however would the hgh still be usable considering it is , and by clear up do u mean the bubbles completely go away , and what would it mean if it didn’t completely go away ? Still usable ?

Degradation is never 100% or nothing.

Maybe it costs 3% of useable rHGH, or 30% (that would probably be close to worst case scenario.).

What you should do, regardless of whether you see bubbles or not, is filter it into a good quality vial. This will remove the things (large aggregates) we’re most concerned with that this process can generate.

In other words, it’s not “I see bubbles should I toss it”, it’s just a visible reminder of one of many reasons to “clean up” the rHGH by filtration prior to use.

 

[lokit]

Normal, happens to me too.