IS CROSS REACTIVITY AN ISSUE in E2 BLOODWORK?

[Dav1D3XT]

Hi, i was wondering if taking aromasin couple hours before doing e2 bloodwork could cause cross-reactivity and cause falsely elevated e2 levels. I'm asking this because last month I took e2 bloodwork and took 25 mg of aromasin 1-2 hours before blood withrawal and they came to be 30 pg/ml
I was wandering if I simply bought bunk aromasin (i took deus medical aromasin) or It was effective and caused cross-reacivity

 

[Sera]

Hi, i was wondering if taking aromasin couple hours before doing e2 bloodwork could cause cross-reactivity and cause falsely elevated e2 levels. I'm asking this because last month I took e2 bloodwork and took 25 mg of aromasin 1-2 hours before blood withrawal and they came to be 30 pg/ml
I was wandering if I simply bought bunk aromasin (i took deus medical aromasin) or It was effective and caused cross-reacivity
View attachment 365864

If you are natty it’s impossible to crush your estrogen to 0 with exemestane. Did you get any other bloodwork or just estradiol?

 

[Cman90]

Mandic S, Kratzsch J, Mandic D, Debeljak Z, Lukic I, Horvat V, Gaudl A, Seric V. Falsely elevated serum oestradiol due to exemestane therapy. Ann Clin Biochem. 2017 May;54(3):402-405. doi: 10.1177/0004563216674031. Epub 2016 Sep 28. PMID: 27687081.

Yes this can happen, repeatedly too. The only way to know for sure is to test your estradiol via mass spec or switch to adex because its metabolites don't mimic e2 like asin.

 

[Dav1D3XT]

If you are natty it’s impossible to crush your estrogen to 0 with exemestane. Did you get any other bloodwork or just estradiol?

i only took AI , but shouldn't have been at least in the 10-23 pg/ml range?
I wasn't on T or any other PEDs

 

[Cman90]

i only took AI , but shouldn't have been at least in the 10-23 pg/ml range?
I wasn't on T or any other PEDs

It should have lowered your e2, yes. Did you have a baseline test before you took the asin? Why are you doing this?

 

[Sera]

i only took AI , but shouldn't have been at least in the 10-23 pg/ml range?
I wasn't on T or any other PEDs

No, not necessarily. You HPTA will compensate for reduced estrogen by increasing testicular output and thereby producing intratesticular estrogen which is not affected by exemestane.

 

[Sera]

It should have lowered your e2, yes. Did you have a baseline test before you took the asin? Why are you doing this?

Because he’s a kid trying to stop his growth plates closing

 

[Dav1D3XT]

switch to adex because its metabolites don't mimic e2 like asin.

This I did e2 bloodwork while on 2.5 mg/day of letro but still they came "high" ; 28,9 pg/ml. I think they should have been much lower considering the dosage and the fact that I don't take any PEDs

 

[Dav1D3XT]

This I did e2 bloodwork while on 2.5 mg/day of letro but still they came "high" ; 28,9 pg/ml. I think they should have been much lower considering the dosage and the fact that I don't take any PEDs

but I think I simply got bunk letro from driada

 

[Cman90]

Because he’s a kid trying to stop his growth plates closing

Smh. TikTok is really going to screw up this new generation of kids.

 

[buck]

No, not necessarily. You HPTA will compensate for reduced estrogen by increasing testicular output and thereby producing intratesticular estrogen which is not affected by exemestane.

Unless the brain thinks there is enough test already in the system.

 

[Dav1D3XT]

Unless the brain thinks there is enough test already in the system.

What should I do/take to "make the brain think there is enough test in the system"?

 

[buck]

What should I do/take to "make the brain think there is enough test in the system"?

I think you have a lot of reading and learning to do before you continue down your path.So you have an understanding of how things work.