PhD in sport science but still clueless

LH, FSH?
Free T with what method? Units?



Why?
Result?


Welcome to MESO.

Congrats.
LH: 3.3 mIU/mL
FSH: 2.94 mIU/mL
Free T: 8.1 ng/dL (direct immunoassay)

Urologist chose Enclo since ill be family planning mid 2026. When I asked about T therapy in conjunction with HCG, Dr advised enclo was an appropriate first step

No follow up labs yet. Been on enclo for 4 weeks, follo up labs are at 12 weeks.

Symptoms wise since starting enclo - morning wood is a bit more regular. Nothing else out different from pre enclo days
 
LH: 3.3 mIU/mL
FSH: 2.94 mIU/mL
Free T: 8.1 ng/dL (direct immunoassay)

Urologist chose Enclo since ill be family planning mid 2026. When I asked about T therapy in conjunction with HCG, Dr advised enclo was an appropriate first step

No follow up labs yet. Been on enclo for 4 weeks, follo up labs are at 12 weeks.

Symptoms wise since starting enclo - morning wood is a bit more regular. Nothing else out different from pre enclo days
Interesting spot. Almost borderline secondary or could be your perfectly fine numbers. Hard to tell without prior data.

The direct FT estimate is problematic so if you wanted to follow up use TT by LCMS along with SHBG to calculate FT with Vermeluen equations. Or pull an equilibrium dialysis assay. They are usually within 20% of each other.

I started with hCG and it worked great. But just had to move to TRT and then TRT++++ then gear abuse. Be careful with Test, gateway to all kinds of good and evil.

Take care.
 
Interesting spot. Almost borderline secondary or could be your perfectly fine numbers. Hard to tell without prior data.

The direct FT estimate is problematic so if you wanted to follow up use TT by LCMS along with SHBG to calculate FT with Vermeluen equations. Or pull an equilibrium dialysis assay. They are usually within 20% of each other.

I started with hCG and it worked great. But just had to move to TRT and then TRT++++ then gear abuse. Be careful with Test, gateway to all kinds of good and evil.

Take care.
SHBG is 32.2 nmol/L

Ill ask my Urologist to see if we can leverage those testing methods you mentioned, otherwise im at the mercy of my provider.

Im curious about TRT, but that same curiosity will certainly take me to TRT platinum elite package.

Im skeptical about UGL sources so I would rather get from pharmacy but then again, my medical provider won't rx me the platinum elite doses that Ill want to explore eventually
 
In my experience, both professionally and in the fitness industry, you sir are an anomaly if you think this way. It is appreciated.
I appreciate the compliment.

To share some more personal experience, I stopped learning jujitsu once I got promoted to blue belt. I thought I knew it all, took me a almost a year of frustration and platuead skill to realize that mentality was holding me back. Humbled myself, began being curious again, asking alot more questions, and my skill set began to improve.

I must apply same mentality here. Im curious and I have questions. Here to learn.
 
Hi Meso,

Stumbled upon Meso ~2months ago and have enjoyed reading through the threads.

I have a PhD in sport science but never cared to learn about enhanced training. Ive been lifting since high school and playing team sports since grade school.

I just Recently finished my phd (34 years old), got a physical done along with labs and to my surprise i had a poor hormonal panel.

Have had labs twice now, and Total T in low 400s, free T in single digits, E2 <25. And had numerous symptoms - gaining fat, hard to put on muscle, very low libido, no morning wood.

Been taking training alot more seriously since school finished. Body fat % down from 22 to 16%, been on a more regimented lifting routine (4×/wk) and consistent with bjj again (3-4×/wk | blue belt)

My urologist put me on enclo 12mg ED. But naturally I drifted towards exogenous T therapy. So im here to learn from real world users since published data only tells us 1 side of the story.

Cheers!
once you got the sperm collected& frozen, you can go balls to the wall with gear.
Maybe 125 test, Maybe 250, 300 if you are feeling really crazy and risky.
as soon as you got your first shot of test in your body, throw out/ donate the enclomiphene. you will never need it again.
After that, the world is your oyster. I personally would wait a year or two until moving on to more serious compounds, so use those to get your response to test (and maybe low dose GH) figured out.
 
Thank you for the insight.

Im curious about a high enough dose to get me at top end of "normal" physiological ranges for all important markers.

The hold ups are:
fertility
high estrogen effects
Hair loss
injecting myself

Im looking to learn more about how people on here have maintained fertility while on therapy, dosages of AI if/when high estrogen effects occured.

Ive used finasteride from HIMS in the past, but killed my libido so I stopped. Since I have disposition to hair loss, its a concern with going higher on T dosage.

Ill eventually just have to suck it up and be okay with the pinch of injecting myself.

freezing my sperm is worth investing, i have not thought about that. Time to do some googling
once you got the sperm collected& frozen, you can go balls to the wall with gear.
Maybe 125 test, Maybe 250, 300 if you are feeling really crazy and risky.
as soon as you got your first shot of test in your body, throw out/ donate the enclomiphene. you will never need it again.
After that, the world is your oyster. I personally would wait a year or two until moving on to more serious compounds, so use those to get your response to test (and maybe low dose GH) figured out.
 
also, huge congrats on getting a PhD. now you just have to get huge and mog everyone at conventions/ while presenting research to your peers.
Lol thank you very much.
Ive presented at conferences before, and youre not wrong. Presenters who have some size on them definitely have a different energy to them.

The health science academic world is a very very close neighbor to your typical fitness convention. You're judged by your appearance.

If youre presenting on a topic of hypertrophy or muscular strength, and you dont look the part, you're absolutely judged.

Just personal stats (InBody 570 data)
Im 5'9
175lbs
16% BF
85lbs skeletal muscle mass
110lb body water

Im not exactly the poster child for "top human performance"
 
Lol thank you very much.
Ive presented at conferences before, and youre not wrong. Presenters who have some size on them definitely have a different energy to them.

The health science academic world is a very very close neighbor to your typical fitness convention. You're judged by your appearance.

If youre presenting on a topic of hypertrophy or muscular strength, and you dont look the part, you're absolutely judged.

Just personal stats (InBody 570 data)
Im 5'9
175lbs
16% BF
85lbs skeletal muscle mass
110lb body water

Im not exactly the poster child for "top human performance"
gotta add 60lbs over the next few years then, to earn tenure, yknow?
high estrogen effects
Hair loss
injecting myself
Aromatase inhibitors,
5-ar inhibitors
and getting some nice premium needles. Makes Injections 1000x better.

and maybe avoid DHT derivatives if hair loss is a really big issue.
Antioxidants also help against acute shedding, which occurs when increasing dosages quickly.
 
Im curious about a high enough dose to get me at top end of "normal" physiological ranges for all important markers.
It varies so much for everyone dude. When I started with 175mg test a week, split across 25mg every day- my total test went from 630 to 1,631 and my estradiol went to 100

There are dudes here who can run 250mg test a week and get total test of 1,400 and an estradiol of 40

Do baseline bloodwork first

Then decide on a starting dose, run it for 30 days an retest

Gauge your response, and adjust from there.

The baseline bloodwork is very important. I would also make sure to check your natty IGF-1. There is lots of good info about what tests to order and the best places to buy them in the serum blood testing forum.

(InBody 570 data)
300px-We_Don't_Do_That_Here.webp

Dexa is second best only to being honest with your self about what's in the mirror.

With some time and experience you will learn to know what your fat percentage is by looking at yourself. Your striations and vascularity

Just shoulder veins, 20%+, Quad veins / feathering starting 15%, chest veins, 12%, ab veins 10%, full glute striations, sub 10%
 
Can I get nice premium needles on Amazon? Or is it pharmacy direct (script needed)?

How will I know if they are premium needles?
There are links to vendors scattered throughout various topics here- but if you google search nipro or terumo or exel needles you will find tons of sites.

Spend some time learning the difference between insulin syringes, luer lok syringes and luer slip. You won't nee a volume higher than 1ml.
 
Do baseline bloodwork first
Step 1 done: I have 2 sets of blood work (hormone panel) 45 days apart. Both were within points of each othee. But I dont have IGF1 reading. Now thats next on my list.

20% of me wants to wait to see what 12mg of enclo does to my labs at the 12 week follow up with urologist. The other 80% wants to start exploring T therapy! I think I gotta double down on learning what fertility strategies people have used while on T therapy.

I have InBody, skinfold calipers, and bodpod in my lab. While each have their limitations, the value is the longitudinal trend more so that the cross-sectional value itself. Ive also taken circumference measurments of limbs and torso to document trend. This accompanied by bi-weekly mirror selfies have given me an idea of progress.

Down the needle rabbit hole I go!

Thank you for your insight!!
 
But could improve fat oxidation if wenwsnt to be precise lol evenbif its not that significant
Correct. "Statistical significance" states that theres a less than 5% chance of the outcome occurring due to chance.

while one group may have had a superior response, mathematically, it was not superior enough to be noteworthy. However, as ive learned, this community is about "how do I squeeze out the best results from my protocol"

I can't argue against lived experience and anecdotal responses. If fasted cardio is superior for the individual user, by all means.
 
Can I get nice premium needles on Amazon? Or is it pharmacy direct (script needed)?

How will I know if they are premium needles?
Nipro is Goated,
Terumo agani is great as well,
Neoject also exists, but their sizing is not intuitive.
Teqler is a bit dull imo. THey got great syringes tho.
 
Correct. "Statistical significance" states that theres a less than 5% chance of the outcome occurring due to chance.

while one group may have had a superior response, mathematically, it was not superior enough to be noteworthy. However, as ive learned, this community is about "how do I squeeze out the best results from my protocol"

I can't argue against lived experience and anecdotal responses. If fasted cardio is superior for the individual user, by all means.
Imho fasted cardio put more stress in the body, also depend on intesities like if its sub lt1 maybe ur gtg but doing an effort at high lt 1 or fatmax is another thing
But for sure u know 100 times more than me abt these things (:
 

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