poor guy...what's the story here?
MESO-Rx
Anabolic Steroids
GH forehead growth
- Thread starter Dr. Eatbox
- Start date
Stealth500
Member
i was joking, but the thought crossed my mind that minoxidil increases the blood flow to that specific area when applied topically so there is some sort of precedent. Increasing blood flow/increasing nutrients into the muscle. I'm suprised nobody is making a cocktail of BCAAs for site injection with all the other blends ie. super shred, immune enhancement, lipo-c ect.
Ha I'm sorry I had to check back i accidentally quoted your calfs comment - knew you were joking!
I was asking the other guy if he botoxes his glabellars
To anybody who actually thinks of trying to apply topical min anywhere like there legs ( cant underestimate what some will try) i beleive its exceptionally toxic to dogs and cats, even tiny amounts.
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malfeasance
Member
Just a bad case of cutis verticis gyrata, the condition that was being discussed above, briefly.
Bad case is an understatement.
Makes sense. Along with the gh I started taking 5mg oral minoxidil. After that I started to develop acne in the scalp back of my neck, some also in the crown area. I attributed that to my barber, which I then switch barbers and it still got worse. My dermatologist diagnosed it as acne keloidalis nuchae. I probably developed cvg at the same time.
What was your thinking on your barber being the culprit?
Maybe it's just me but I'm not seeing a bunch of difference here. They thoughtfully used a final picture where he is a little closer to the camera making his face look bigger and his face isn't tilted like it is in every other photo. And he also grew a beard so you can't tell shit about his jaw line anymore.
Old peoples' noses and ears keep growing, my grand dad definitely wasn't taking GH but his nose looked completely different at 70 than it did at 50-60.
Ghoul
Member
That’s a form of age related localized “acromegaly light”.
IGF-1 goes down with age, IGF-1 receptors in muscle, for instance, decline (because of declining androgen levels btw), causing the typical age related muscle loss (sarcopenia).
With less exposure to IGF-1, the remaining receptors try to compensate by increasing sensitivity.
IGF binding proteins decline with age (also, in part, as a result of declining androgens) leaving more of the declining IGF-1 free to bind to receptors.
But in tissues like nose cartilage, IGF-1 receptors levels aren’t influenced by declining androgen hormones, so they don’t disappear like they do in muscle. Since they’re also exposed to lower average levels of IGF-1, they upregulate sensitivity, get saturated by the additional “free” IGF-1 not tied up in binding proteins, with the end result being faster growth than when they were young.
TRT and (physiological levels of) rHGH would actually slow or stop this “old age localized nose acromegaly”.
*....His medical history was notable for coronary artery disease status aftercoronary artery bypass graft of 3 vessels, peripheralvascular disease status after a right femoropopitealbypass, and severe hypertension. His medicationsincluded minoxidil 50 mg daily, labetalol 400 mgdaily, furosemide 320 mg daily, potassium 80 mEq daily, quinapril 20 mg daily, spironolactone 100 mgdaily, simvastatin 40 mg daily, lansoprazole 30 mgdaily, and aspirin 81 mg twice a week..."
....However, IGF-1 and GH levels along with radiographs of the chest and long bones (femora and humeri) were all normal....
Ghoul
Member
Said something similar a long time ago, but agenda needs to agend
Look, without first hand knowledge, what caused his current look is guesswork.
But we know he used rHGH many years ago, because he got busted and went on to not only acknowledge it, but even recently endorsed it in interviews.
The thing is, he’s said some shit that makes it pretty clear he didn’t know what he was doing, and likely following the common advice of using “As much as you can afford.”, which for him, meant a lot more than even most bodybuilders.
He keeps making the point was that although he used it to “get buff”, HGH wasn’t a steroid, and he denied using steroids.
So how much rHGH do you have to use to get an appreciable anabolic boost? A fuckload,
Whether his use was guided by IGF-1 levels (yeah right) or “More is better” there are old timers with an “agenda” that want to hang on to the old “as much as you can afford” philosophy now that its so cheap they can afford to use it at “millionaire” doses indefinitely, denying any harm can come from excessive rHGH use.
My point is simply that for the first time in history, it’s easy for virtually anyone to use as much GH as they want, indefinitely, and unless risk is managed somehow (like watching IGF), there are health risks that will become more apparent over time with more people using it.
Without the narrative being updated to include some consciousness of that risk and how to control it, all irresponsible use will lead to is even tighter regulations and more crackdowns in the future.
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Ghoul
Member
Forget about him as an example.
Do you doubt that supra-physiological levels of IGF-1 over time cause acromegaly?
We know how to manage most risk from AAS, what markers to watch, control, and adjust doses by.
What, if anything, guides safe rHGH use, especially now that cost no longer constrains its use.
You have an agenda that is not backed by real word incidence or prevalence. I said it before and i will say it again.
Just got tired of arguing with you.
The principle remains Common things occur commonly.
You go about dragging clinical reports of cases with rare occurrences and posit them here as if it's sole unshakable Lore.
It's tiring but has zero bearing on harm reduction (i e , it's not making anyone unsafe) hence my reluctance to drag what is essentially an academic debate
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It's hard to forget about him when you used the image to bolster what is still unfolding science.
Bruh if you want to 'educate the bros' about Minoxidil and it's effects use this article instead
New Target for Minoxidil in the Treatment of Androgenetic Alopecia - PMC
To investigate the mechanism of minoxidil in treating androgenetic alopecia (AGA). The mechanism of action of minoxidil on AGA was first systematically investigated from the viewpoint of network pharmacology, including minoxidil-AGA target ...
pmc.ncbi.nlm.nih.gov
It posits several theories about how minoxidil interacts with receptors to produce its effects.
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what source?
Yes i had deep 11 lines and now they are GONE! Botox (or other toxin) to paralyze and atrophy the muscle. This also stops the lines from getting worse. Then I had PDO threads put in. It`s dissolvable surgical suture that stimulates collagen growth to "fill in" those 11 lines. We do it in our clinic for $160. You in AZ?
No unfortunately, not US. Interesting though thanks. PDO sounds next level.
I've now had botox. Massive difference. No longer look so stressed.
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