First time HGH

[BigDadd7]

Last time I got it tested when I got my 425 IGF, my estrogen was 49.

What was your T level?

 

[niqTM]

What was your T level?

1324

 

[Ghoul]

So, theoretically, since my IGF is higher on 4iu, that means, theoretically, my estrogen is lower?

There are many factors that impact IGF levels at the same rHGH dose.

TLDR Estrogen is “permissive” for IGF-1 production.

Limiting this to Estrogen’s impact only, if all other conditions are equal:

-A very small amount is necessary for normal IGF-1 production.

- male physiological range doesn’t interfere.

- very high levels inhibit IGF-1

———-

Stated another way:

If estrogen is crushed (below ~15pg) IGF-1 production is inhibited = insufficient for normal liver function = lower IGF-1

If estrogen is in male physiological range or mildly elevated (~15-80) IGF-1 production is uninhibited = No “estrogen IGF brake” = IGF-1 determined by other factors

If estrogen is very high, (above ~80-100) IGF inhibition begins = “stepping on estrogen IGF-1 brake” = lower IGF-1

 

[Drizz]

Tesamorelin 2mg is roughly the same boost to growth hormone / IGF as 2iu rHGH, though the effects are a tilted more strongly toward visceral fat reduction vs rHGH having a broader range of effects, and it took about 4 months of Tesa for the impact to go from maybe / “Feels” to undeniable visible benefits.

I strongly recommend @Rooster77 and anyone else going down this road to get a baseline IGF-1 blood test before starting. It’s your only chance to know you started so you can get an objective measure of rHGH (or Tesa) having an impact.

Don’t get lazy, if you don’t do this, while not a catastrophe, you’ll probably regret not getting a “clean” IGF number before you ever touch rHGH.

A month or so after starting, if you’re wondering “is this working”, for ~$60 you can see a concrete number that will remove any doubt. IGF also serves as an indicator of other factors that may be blunting the GH effect, so you can troubleshoot the root cause of a poor response (as a bonus, this may reveal health issues you were unaware of like hypothyroidism or fatty liver). Conversely, if you’re a hyper responder you may decide to dial your dose back a little for safety. You want your IGF “Z score”, a positive number indicates how far above your peer average IGF is, to be as close as possible to 2, but absolutely not over 3, for max benefit with minimal long term risk.

There are a number of services offering easy to schedule discount blood work at a lab convienient to you, I use this one, there’s always a 20% off coupon going so use it:

IGF-1 Test

The IGF-1 Test checks growth factor levels, providing insight into growth disorders, hormone balance, pituitary health, aging, and overall metabolic function.

www.ultalabtests.com

@Ghoul thanks for all your info.
I’ve been running Reta since June, I am about to start Tesa at 2mg/night fasted before bed, but been looking at HGH to run with Test C, Primo and Mast for a 12 wk run as a HGH first timer at 50 years old.

 

[Ghoul]

@Ghoul thanks for all your info.
I’ve been running Reta since June, I am about to start Tesa at 2mg/night fasted before bed, but been looking at HGH to run with Test C, Primo and Mast for a 12 wk run as a HGH first timer at 50 years old.

Don’t worry about timing with Tesa. Any time of day, just consistent, is fine. Its effect is long lasting and amplifies your natural GH release. Eating before or after dosing makes no difference to its effect.

That said eating before bed can dampen natural GH release, when it would normally peak overnight, so it’s a good idea to stop eating a few hours prior anyway.

 

[Drizz]

Don’t worry about timing with Tesa. Any time of day, just consistent, is fine. Its effect is long lasting and amplifies your natural GH release. Eating before or after dosing makes no difference to its effect.

That said eating before bed can dampen natural GH release, when it would normally peak overnight, so it’s a good idea to stop eating a few hours prior anyway.

Got it. Appreciate that. Everything I’ve read about it has it best, fasted and before bed.
Is there an added benefit of running Tesa with GH when the time comes? Thanks

 

[MJMoor]

im 47 running test cyp total t <1500 e2 low 40s have been running 3mg reta week for around a year same time i started my test, my fasting morning glucose was high 90s i add 4iu gh at night 3 months ago and my morning fasting glucose his went to 110-120 same micros ,will it help any to take my gh in the morning with my glucose or should i up the reta?

 

[Ghoul]

Got it. Appreciate that. Everything I’ve read about it has it best, fasted and before bed.
Is there an added benefit of running Tesa with GH when the time comes? Thanks

No. rHGH drops natural production of GH to zero. Tesa only *amplifies* existing production. 50% more of zero is zero.

It can be useful to cycle off rHGH, (natural production quickly resumes), switch to Tesa for a few months to give GH receptors time to resensitize, while maintaining elevated GH to keep progress made on rHGH.

The reason Tesa reduces visceral fat like the equivalent of a much higher dose of rHGH, is because by keeping the natural growth hormone pulses in place, receptors don’t down regulate sensitivity the way they do when exposed to unnatural continuous rHGH exposure, so the “hear” smaller amounts of GH, releasing fat, vs rHGH which makes them a little “deaf” temporarily to growth hormone signals.

 

[Lobsterneck7]

I’m getting ready to start my first HGA cycle. I’m going to run probably 500mh of test cup with it

What can I expect from the HGH?? (4iu a day.)

Considering your diet, recovery, and training are where they should be, you should expect some more fullness and better sleep/recovery relatively soon. Weight might come up a bit but in a good way. Maybe some CTS, numbness or tingling. Overall GH is a slow burn compared to the quick hit of anabolics so it’s more so something you will reap a majority of rewards from over a longer period of time. Small percentages each day that eventually add up to some pretty solid results over a period of months and years.

 

[Drizz]

No. rHGH drops natural production of GH to zero. Tesa only *amplifies* existing production. 50% more of zero is zero.

It can be useful to cycle off rHGH, (natural production quickly resumes), switch to Tesa for a few months to give GH receptors time to resensitize, while maintaining elevated GH to keep progress made on rHGH.

The reason Tesa reduces visceral fat like the equivalent of a much higher dose of rHGH, is because by keeping the natural growth hormone pulses in place, receptors don’t down regulate sensitivity the way they do when exposed to unnatural continuous rHGH exposure, so the “hear” smaller amounts of GH, releasing fat, vs rHGH which makes them a little “deaf” temporarily to growth hormone signals.

Thanks so much @Ghoul. Love the 50% more of nothing is nothing. I use that in business.

 

[mumblesrumbles]

Hi relatinvely new to hgh(have taken for 1yr brilliant) as in its been a long time ruffly 10yrs and back then it was 100iu kits i got
Now ive orderd 24iu x 10 so does that make 2.4ml water per vial also how long does the vial last after reconsituation ?
Ideally would like to run 2iu initially bit that would mean its sat for nax 12 days any help appreaciated thanks

 

[Cato1989]

.

 

[Ghoul]

Hi relatinvely new to hgh(have taken for 1yr brilliant) as in its been a long time ruffly 10yrs and back then it was 100iu kits i got
Now ive orderd 24iu x 10 so does that make 2.4ml water per vial also how long does the vial last after reconsituation ?
Ideally would like to run 2iu initially bit that would mean its sat for nax 12 days any help appreaciated thanks

That reconstitution amount of water is ideal.

No one can answer how long a particular batch of rHGH lasts post reconstitution, but the sooner it’s used, the better. 12 days isn’t excessive.

Consider getting your IGF-1 tested. That’s a much better way to determine if your dose is safe for long term use than IU.