Blood Pressure

[newguy2]

And is Cilnidipine available now in October of 2025? I have been away for a while and have not kept up with all of the trials and tribulations of customs and tariffs and so on.

If you mean through a pct vendor than yes. Cheap too.

 

[Ghoul]

beta blocker

my doctor added metoprolol to my telmisartan when the max dose of telmi failed to produce sufficient lowering of blood pressure.

They seem to work well together.

In plain English, is there some concern about me taking metoprolol ??? Stroke? What is this about?

Yes. It doesn't lower "central" blood pressure. So while BP looks good at the arm, the brain is exposed to high blood pressure. As an aside, I watched my grandfather, BP seemingly controlled, have a paralyzing stroke right in front of me. He had been on Metoprolol. Nebivolol is safer if a beta blocker must be used (in case of heart failure or reduced ejection fraction). Otherwise a CCB is preferred for better outcomes.

And is Cilnidipine available now in October of 2025? I have been away for a while and have not kept up with all of the trials and tribulations of customs and tariffs and so on.

Packs are flowing from India. Our favorite "round the clock" vendor has a low priced option that costs less than $20 for a year's worth.

I also able to establish Cilnidipine is a very stable med. 5 years is absolutely no issue even at normal room temp (up to 74f). In a cool spot or the fridge, in those great aluminum India. blister packs, it's probobly good for decades, given its very slow rate of degradation.

I use a combo Telm 40mg / Ciln 20 tab, and it's been fantastic, benefits going beyond just BP and no sides.

 

[explodingHeart]

Yes. It doesn't lower "central" blood pressure. So while BP looks good at the arm, the brain is exposed to high blood pressure. As an aside, I watched my grandfather, BP seemingly controlled, have a paralyzing stroke right in front of me. He had been on Metoprolol. Nebivolol is safer if a beta blocker must be used (in case of heart failure or reduced ejection fraction). Otherwise a CCB is preferred for better outcomes.



Packs are flowing from India. Our favorite "round the clock" vendor has a low priced option that costs less than $20 for a year's worth.

I also able to establish Cilnidipine is a very stable med. 5 years is absolutely no issue even at normal room temp (up to 74f). In a cool spot or the fridge, in those great aluminum India. blister packs, it's probobly good for decades, given its very slow rate of degradation.

I use a combo Telm 40mg / Ciln 20 tab, and it's been fantastic, benefits going beyond just BP and no sides.

Did you have any other mini-discoveries aside from Ciln and Pitiva?

Ciln has really improved my behavior. I used to rage out at only 250mg test at least once a week at this and that. I've only had one anger episode in 2 months since I started. I feel calmer over all taking 10mg of Ciln.

 

[just some dude]

Did you have any other mini-discoveries aside from Ciln and Pitiva?

Ciln has really improved my behavior. I used to rage out at only 250mg test at least once a week at this and that. I've only had one anger episode in 2 months since I started. I feel calmer over all taking 10mg of Ciln.

indapamide maybe

 

[just some dude]

Did you have any other mini-discoveries aside from Ciln and Pitiva?

Ciln has really improved my behavior. I used to rage out at only 250mg test at least once a week at this and that. I've only had one anger episode in 2 months since I started. I feel calmer over all taking 10mg of Ciln.

sorry i didn’t read the last part when i said indapamide, i meant that part for a mini discovery because i also started researching clin and pita from ghoul’s posts. you can try clonidine for the rage it’s a very similar mechanism of action to the part of clin lowering adrenaline

 

[Banana Joe]

Ok, then 120/70 it is, or as close as possible. I also need this Cilnidipine, since it apparently prevents and can apparently also regress plaque. ... Don't need that stroke from Nebi, I guess.

LOL, I finally managed to figure out how to use my BP device, the internet says it is very precise and this is what my BP was yesterday, after waking up:

100/72/65

I didn't expect my BP to be that much higher from riding my bike to the cardiologist....
I must note that I involuntarily lost some weight over the last 5 weeks or so, but equally haven't done my cardio, so I guess that is a wash in the end.
I guess RHR could be lower, but I am also taking a shitload of ADHD meds and Bupropion.
At least I now know I wasn't hallucinating, that my BP was still fine (didn't remember then numbers from back then) when I was almost 100kg at running Tren and Sdrol.

 

[Nixonnow99]

LOL, I finally managed to figure out my BP device, the internet says it is very precise and this is what I had yesterday after waking up:

100/72/65

I didn't expect my BP to be that much higher from riding my bike to cardiologist....
I must note that I involuntarily lost some weight over the last 5 weeks or so, but equally haven't done my cardio, so I guess that is a wash in the end.
I guess RHR could be lower, but I am also taking a shitload of ADHD meds and Bupropion.
At least I now know I wasn't hallucinating, that my BP was still fine (didn't remember then numbers from back then) when I was almost 100kg at running Tren and Sdrol.

Which device are you using?

 

[Banana Joe]

Beurer 54 or smth like that.

 

[aaronben]

re: nebivolol

Because it mainly works by slowing the heart and reducing output, not by relaxing or healing blood vessels — so it lowers numbers, but not the root cause of essential hypertension.





Simplified:

• Hypertension = mostly a vascular resistance issue (stiff arteries, overactive RAAS).
• ARB/CCB fix that directly (they relax arteries and block angiotensin).
• Nebivolol just makes the heart pump slower/weaker → BP drops artificially, but arteries stay tight.

So while it looks effective on paper, long-term studies show less organ protection and higher stroke/metabolic risk vs ARB + CCB + thiazide.


That’s why it’s the “wrong pathway” for most people unless there’s a cardiac reason to need it.

1. ARB / ACE inhibitor
2. Calcium channel blocker
3. Thiazide diuretic
4. Beta-blocker
5. Alpha-blocker
6. Central agent

A beta-blocker based on bisoprolol, used to treat chronic stable heart failure. It belongs to the class of selective beta-1 blockers, which are drugs that work by reducing the activity of the sympathetic nervous system on the heart. This effect slows the heart rate and reduces the heart's workload, improving its efficiency.

Here are the product's features:

Regulates heart rate: It works by slowing the heartbeat and contributing to a more regular and controlled rhythm;
Treats heart failure: It improves the heart's ability to pump blood more effectively, reducing the risk of worsening;
Reduces associated symptoms: It helps relieve symptoms such as fatigue, dyspnea, and edema, improving the patient's quality of life.

Everyone should use this beta blocker if they are using steroids, it makes you breathe much better and the heart rate drops significantly, also more oxygen to the heart

 

[aaronben]

Thanks. I'm currently on Telmisartan 40mg & Nebivolol 10mg (Nebi doc prescribed). However, this thread is making me rethink. Gonna have to place an order with PCT India soon.

Domestically available Amlodipine's edema side effects don't sound like something anyone wants to deal with.

Older molecules with fewer side effects, such as ramipril +bisoprolol, work better

 

[adrenalytic]

Everyone should use this beta blocker if they are using steroids, it makes you breathe much better and the heart rate drops significantly, also more oxygen to the heart

If it does all these things then shouldn't everyone use it? Why limit it to steroid abusers?

 

[jford25]

I’m in my mid 30’s, at a healthy weight with about 15% body fat, my diet isn’t perfect but it’s solid. I use 200mg of Testosterone per week and 7mg Reta, 0.8mg Sema. I do pretty intense cardio for about 1 hour 4 times a week and weight lifting 3-4 times a week. Despite all this my blood pressure is usually within 5 points of 135/80. My doctor thinks it’s no big deal tells me to eat more vegetables lol he said he only considers prescribing people my age if it’s 140/90 or higher. I’ve been thinking about ordering some cilnidipine. What do you guys think? I’d love my bp to be below 120/80 at all times and believe it’d be beneficial for me to take bp medication

 

[Lifting88]

I’m in my mid 30’s, at a healthy weight with about 15% body fat, my diet isn’t perfect but it’s solid. I use 200mg of Testosterone per week and 7mg Reta, 0.8mg Sema. I do pretty intense cardio for about 1 hour 4 times a week and weight lifting 3-4 times a week. Despite all this my blood pressure is usually within 5 points of 135/80. My doctor thinks it’s no big deal tells me to eat more vegetables lol he said he only considers prescribing people my age if it’s 140/90 or higher. I’ve been thinking about ordering some cilnidipine. What do you guys think? I’d love my bp to be below 120/80 at all times and believe it’d be beneficial for me to take bp medication

If my bloodpressure was at 135 i will take it

 

[hexagonal]

I’m in my mid 30’s, at a healthy weight with about 15% body fat, my diet isn’t perfect but it’s solid. I use 200mg of Testosterone per week and 7mg Reta, 0.8mg Sema. I do pretty intense cardio for about 1 hour 4 times a week and weight lifting 3-4 times a week. Despite all this my blood pressure is usually within 5 points of 135/80. My doctor thinks it’s no big deal tells me to eat more vegetables lol he said he only considers prescribing people my age if it’s 140/90 or higher. I’ve been thinking about ordering some cilnidipine. What do you guys think? I’d love my bp to be below 120/80 at all times and believe it’d be beneficial for me to take bp medication

If you're averaging 135/80, you're averaging stage 1 hypertension.

Damage from high blood pressure on a variety of your body parts is cumulative and irreversible.

 

[jford25]

If you're averaging 135/80, you're averaging stage 1 hypertension.

Damage from high blood pressure on a variety of your body parts is cumulative and irreversible.

My exact average is 133/79 per my bp machine. I rounded to nearest multiple of 5 for sake of “nice numbers” haha

That makes sense and what I’ve read also indicates that. It’s frustrating doctors sometimes downplay and act so nonchalant about real issues.

Another example is my mother-in law who has CKD with a GFR of 35-50 past couple years on her blood tests. Her doctor doesn’t want to add on any additional bp med with her average being 140/90. She takes amlodipine 5mg twice a day. She’s also hasn’t been referred to a nephrologist which is crazy in my book.

 

[Nixonnow99]

My exact average is 133/79 per my bp machine. I rounded to nearest multiple of 5 for sake of “nice numbers” haha

That makes sense and what I’ve read also indicates that. It’s frustrating doctors sometimes downplay and act so nonchalant about real issues.

Another example is my mother-in law who has CKD with a GFR of 35-50 past couple years on her blood tests. Her doctor doesn’t want to add on any additional bp med with her average being 140/90. She takes amlodipine 5mg twice a day. She’s also hasn’t been referred to a nephrologist which is crazy in my book.

If true about your MIL. She needs to find a new doctor immediately. Current doc is ignoring and contributing to irreversible damages. An eGFR of 35-50 is stage 3b kidney disease.

 

[Halldohr]

I use Telme 80mg and Nebivolol 5mg and when i test my BP after 45min or so its at 115/67 but the strange thing at the blood donation appointment they are testing bp too and i have 150/75 or so, i think this happen because i have to stand up and sit down for 4 times before i arrived the bp testing station. I dont know but thats a bit strange

 

[RzSco]

I just got a 150/70 … isolated systolic hypertension, anyone know what drugs are best to deal with that? I don’t want to end up with diastolic hypotension.

Tbh I’m never really at my resting heart rate when I do this cause it takes hours of sitting sedentary to get there but I think even 150 one hour post workout and consuming a non-caffeine PWO is way too high.

Diastolic has stayed down but systolic has crept up again despite my 6 hours a week cycling and lowering my TRT even further. I’m not currently on any BP med because it was OK for a while.

 

[sionnach]

I just got a 150/70 … isolated systolic hypertension, anyone know what drugs are best to deal with that? I don’t want to end up with diastolic hypotension.

Tbh I’m never really at my resting heart rate when I do this cause it takes hours of sitting sedentary to get there but I think even 150 one hour post workout and consuming a non-caffeine PWO is way too high.

Diastolic has stayed down but systolic has crept up again despite my 6 hours a week cycling and lowering my TRT even further. I’m not currently on any BP med because it was OK for a while.

Not only is it high, but the ratio is troublesome too. What's in your PWO?

 

[Eddie.]

I just got a 150/70 … isolated systolic hypertension, anyone know what drugs are best to deal with that? I don’t want to end up with diastolic hypotension.

Tbh I’m never really at my resting heart rate when I do this cause it takes hours of sitting sedentary to get there but I think even 150 one hour post workout and consuming a non-caffeine PWO is way too high.

Diastolic has stayed down but systolic has crept up again despite my 6 hours a week cycling and lowering my TRT even further. I’m not currently on any BP med because it was OK for a while.

Damn, this is how i am too. My diastolic never goes above 65 but thankfully the highest I've seen my systolic is at 120's.

I do wonder though which would be the best course of treatment for ISH without dropping diastolic too low? Is it telmisartan? Is it amlodipine?

Honestly i think it would be better to have both values raised and just take a blood pressure med, now you’ll have to be very careful not to destroy diastolic.