Visceral growth, especially intestines, is one of the first acromegalic effects from excess IGF for too long. rHGH is actually pretty useful for renewing intestines by thickening the walls, which makes nutrient absorption better, and blocks endotoxin from entering the bloodstream (aka "leaky gut"). Since endotoxin triggers systemic inflammation, when it's stopped aches and pains are reduced, mental clarity improves, immune function fights off illness more effectively, overall sense of wellbeing goes up. rHGH is used "off label" post intestinal surgery to speed healing.
Of course, "too much of a good thing" and you end up with Pulumbo gut.