Is it Primo? or is it EQ?

[k710]

Hey all,

I wanted to ask for some opinions on my current compound situation and labs.

Quick recap:
So I started my first t-cycle on 7/4/25 with 200mg test-c weekly split into daily IM injections.
4 weeks later, I pulled labs again to see how things were going. E2 was at 22.1. T levels were at 1402.
Decided to bump T up to 300 to push e2 a bit higher and find my estrogen threshold.
3 weeks later, e2 sides came in hot. Ran e2, results came back at 60H. Threshold found.
Decided to introduce a low dose Primo.. 30mg 2x/week to manage estrogen. 3 weeks later, repulled labs and e2 came back at 32.
Began feeling pretty crapy, body was hurting, hair shedding like crazy, skin dry, bloated pretty quickly, and fatigued w/ heavy brain fog
Concerned, I ran testing again on 10/9 and T levels were 1524 and e2 came back at 9.

Concerns:
-LOWW estradiol; Long ester, best way to restore
-Primo at such a small dose shouldnt cuz e2 so drastically from what Ive read.
-Im assuming it was faked with EQ, but the cut in e2 almst seems too aggresive for 60mg/week dosage of EQ.
-Addressing e2, finding a different path forward without using this mystery compound throwing off all my testing.

Options for e2:
- Keep "prim.EQ" in place and raise testosterone a bit to help e2 recover while dealing with the long ester. Get e2 to healthy range and maintain.
- Cut "Prim.EQ" out and allow e2 to recover. Control e2 with AI or try mast-p to see if it affects estrogen for me.
- Cut questionable compound, bump test to recover e2, once in healthy range introduce Mast-p or NPP.
- Reconsider Primo when trusted source has avaialble again.
- Get E.Q from trusted source when becomes avaialbe again (this time knowing compound and tested strength)

Blood work:

7/2/25 - Pre-ped baseline
Test - 608
TSH 1.300
Prolactin 15.7
PSA 0.5
Estradiol 23.3 (sensitive)

8/18/25 - 6 week follow labs
Test - 1402
Estradiol - 22.1 (standard)

9/11/25 - 3.5 weeks later (Test up to 300mg)
Estradiol - 60 (standard)

9/29/25 - "Prim.EQ" introduced at 30mg 2x/week (60mg/week)
Estradiol - 34 (standard)

10/09/25 - "Sensitive testing for confirmation"
Total Test (MS) - 1524
Estradiol LC/MS - 9
Prolactin - 14.4

Any suggestions on how you would move forward would be greatly appreciated. I have lab review consultation with my coach on wednesday, but Im technically suppossed to pin second compound today and leaning towards pinning it but boosting my T say 50mg/week.

Im about to do a complete brand swap to utilizing Primal's products exclusively;
Test-E, NPP and Mast-P on hand. EQ should be back soon and Ill have that in the stash.

Feel like I took a crash course in Estrogen. Experienced high and low e2 symptoms in 4 week timeframe, at least I got it out of the way early lol

 

[BigDadd7]

Short of testing on your primo/eq, theres no way to know for sure.

With that said, it's unlikely eq would lower your e2 more than primo would. Especially at that low of a dose.

The difficulty comparing the e2 is that you went from standard to sensitive. Those numbers will always be different. So, you can't compare them.

You're changing dosages, adding stuff, and changing testing methodologies every few weeks. You have a lot of data, but none of it is useful. Run just the test for 4 weeks. Recheck test/e2 sensitive. From that baseline, you can begin to experiment with a low dose of your new gear.

Or, just say F-it and keep trying random stuff hoping to get lucky. This is a long game with no trick shots.

 

[Buffed Shark]

How long were you using primo before that 9/29 test? Also what makes you think its eq and not primo, based on your date and story telling it does look like it could be overdosed primo or injectable ai which what i've been hearing many people finding in their primo, where did u get it?

 

[k710]

Short of testing on your primo/eq, theres no way to know for sure.

With that said, it's unlikely eq would lower your e2 more than primo would. Especially at that low of a dose.

The difficulty comparing the e2 is that you went from standard to sensitive. Those numbers will always be different. So, you can't compare them.

You're changing dosages, adding stuff, and changing testing methodologies every few weeks. You have a lot of data, but none of it is useful. Run just the test for 4 weeks. Recheck test/e2 sensitive. From that baseline, you can begin to experiment with a low dose of your new gear.

Or, just say F-it and keep trying random stuff hoping to get lucky. This is a long game with no trick shots.

I ran standard E2 due for turnaround time, started growing gyno on one side and felt like 2 weeks would have been too long without taking action. Ive read the threads and convos about standard vs sensitive testing. I see the argument for both sides, but I would be more concerned if the e2 had come back super low on standard. But 60, even if the test is designed for women's higher e2 numbers, is not an extreme in either direction.

I definitely had high e2 with symptoms so it was elevated. e2 at 60 from 300mg of test sure seems normal to me. I believe the drop was from the long ester catching up and eventually crushing e2. Or there is some type of AI in it.
Either way, standard testing was to mitigate the sides I was experiencing. Was only aiming to stop e2 from climbing further. Sensitive testing used to confirm. Remember I was using this thinking it was Primo. 60mg of Primo shouldnt drastically change anyones e2 like what I experienced.

Im very concious about not blindly throwing dosages around or implementing compounds. Test + Primo for AI control was my preference over utilizing Anastrozole (I had on hand for emergencies though). Wasnt even trying to run Primo for the aesthetic.. hence the tiny dose. Obviously the reaction was way unexpected.

I am upset that my data set is skewed with unknown variable. I dont think anyone purposfully tries to make their introduction to cycle as difficult as possible, but shit happened and im going through all the possible options for addressing before making changes.

Ive seen a lot of people utilizing test-p or orals to help get crashed e2 into healthy ranges (especially if crashed with a long ester). Thats where the thought of bumping test 50mg for a couple of weeks would help came from.

Dosage increments after 6 weeks and retesting doesnt seem wild, especially if your goal in that time is to find your estrogen threshold. Coach wanted my trough to be above 1500 T and I wasnt there and my e2 was slightly lower than baseline levels.

Ill prob send off one of the 3 remaining vials of "primo" for testing down the line. Im set on removing it and all other products and sticking with lab tested products from Primal. My priority is getting my shit back in check and when things are normalized, ill deal with getting to the bottom of the mystery variable in my data sets.

Appreciate your insight, and likely to drop the compound in question and let my Test do its thing.

The other compounds are just in my on-hand stash. Its not to utilize them all at once, but to have the options available if I decide to change my approach when e2 is healthy again.

 

[newguy2]

I ran standard E2 due for turnaround time, started growing gyno on one side and felt like 2 weeks would have been too long without taking action. Ive read the threads and convos about standard vs sensitive testing. I see the argument for both sides, but I would be more concerned if the e2 had come back super low on standard. But 60, even if the test is designed for women's higher e2 numbers, is not an extreme in either direction.

I definitely had high e2 with symptoms so it was elevated. e2 at 60 from 300mg of test sure seems normal to me. I believe the drop was from the long ester catching up and eventually crushing e2. Or there is some type of AI in it.
Either way, standard testing was to mitigate the sides I was experiencing. Was only aiming to stop e2 from climbing further. Sensitive testing used to confirm. Remember I was using this thinking it was Primo. 60mg of Primo shouldnt drastically change anyones e2 like what I experienced.

Im very concious about not blindly throwing dosages around or implementing compounds. Test + Primo for AI control was my preference over utilizing Anastrozole (I had on hand for emergencies though). Wasnt even trying to run Primo for the aesthetic.. hence the tiny dose. Obviously the reaction was way unexpected.

I am upset that my data set is skewed with unknown variable. I dont think anyone purposfully tries to make their introduction to cycle as difficult as possible, but shit happened and im going through all the possible options for addressing before making changes.

Ive seen a lot of people utilizing test-p or orals to help get crashed e2 into healthy ranges (especially if crashed with a long ester). Thats where the thought of bumping test 50mg for a couple of weeks would help came from.

Dosage increments after 6 weeks and retesting doesnt seem wild, especially if your goal in that time is to find your estrogen threshold. Coach wanted my trough to be above 1500 T and I wasnt there and my e2 was slightly lower than baseline levels.

Ill prob send off one of the 3 remaining vials of "primo" for testing down the line. Im set on removing it and all other products and sticking with lab tested products from Primal. My priority is getting my shit back in check and when things are normalized, ill deal with getting to the bottom of the mystery variable in my data sets.

Appreciate your insight, and likely to drop the compound in question and let my Test do its thing.

The other compounds are just in my on-hand stash. Its not to utilize them all at once, but to have the options available if I decide to change my approach when e2 is healthy again.

Here is some data from another member that seems pertinent to yours. Notice his standard test came back right where yours was but in reality his e2 was in range.

Kind of hard to be certain first time that you were having high e2 sides. Obviously is gyno was truly growing that needs to be dealt with.

I'm not sure why you are so concerned about running an ai. Seems like a recent fad to avoid them at all costs? Could easily have tossed in low dose aromisin a couple times a week and likely been fine.

 

[Photon]

I ran standard E2 due for turnaround time, started growing gyno on one side and felt like 2 weeks would have been too long without taking action. Ive read the threads and convos about standard vs sensitive testing. I see the argument for both sides, but I would be more concerned if the e2 had come back super low on standard. But 60, even if the test is designed for women's higher e2 numbers, is not an extreme in either direction.

I definitely had high e2 with symptoms so it was elevated. e2 at 60 from 300mg of test sure seems normal to me. I believe the drop was from the long ester catching up and eventually crushing e2. Or there is some type of AI in it.
Either way, standard testing was to mitigate the sides I was experiencing. Was only aiming to stop e2 from climbing further. Sensitive testing used to confirm. Remember I was using this thinking it was Primo. 60mg of Primo shouldnt drastically change anyones e2 like what I experienced.

Im very concious about not blindly throwing dosages around or implementing compounds. Test + Primo for AI control was my preference over utilizing Anastrozole (I had on hand for emergencies though). Wasnt even trying to run Primo for the aesthetic.. hence the tiny dose. Obviously the reaction was way unexpected.

I am upset that my data set is skewed with unknown variable. I dont think anyone purposfully tries to make their introduction to cycle as difficult as possible, but shit happened and im going through all the possible options for addressing before making changes.

Ive seen a lot of people utilizing test-p or orals to help get crashed e2 into healthy ranges (especially if crashed with a long ester). Thats where the thought of bumping test 50mg for a couple of weeks would help came from.

Dosage increments after 6 weeks and retesting doesnt seem wild, especially if your goal in that time is to find your estrogen threshold. Coach wanted my trough to be above 1500 T and I wasnt there and my e2 was slightly lower than baseline levels.

Ill prob send off one of the 3 remaining vials of "primo" for testing down the line. Im set on removing it and all other products and sticking with lab tested products from Primal. My priority is getting my shit back in check and when things are normalized, ill deal with getting to the bottom of the mystery variable in my data sets.

Appreciate your insight, and likely to drop the compound in question and let my Test do its thing.

The other compounds are just in my on-hand stash. Its not to utilize them all at once, but to have the options available if I decide to change my approach when e2 is healthy again.

Only way to know what you're getting is to test it. Add .3ml from each vial to a single vial, that adds up to ~1ml then send that for testing. You can use AB if you're on a budget and they charge 60$.

Primo and Mast will probably be back in stock for alot of sources in the next few months, which will give u time to stock up.

 

[newguy2]

Only way to know what you're getting is to test it. Add .3ml from each vial to a single vial, that adds up to ~1ml then send that for testing. You can use AB if you're on a budget and they charge 60$.

Primo and Mast will probably be back in stock for alot of sources in the next few months, which will give u time to stock up.

If you can afford $200 a vial

 

[k710]

How long were you using primo before that 9/29 test? Also what makes you think its eq and not primo, based on your date and story telling it does look like it could be overdosed primo or injectable ai which what i've been hearing many people finding in their primo, where did u get it?

I hadnt discovered Meso yet and went through Naps using XT-Labs as the vendor.

Overdosed Primo is HIGHLY unlikely, not only because of market conditions, but because its an expensive raw product. Once I got weird results, I went on a mega deepdive of the vendor (discovred meso that way!). Tons of old horror stories, sketchy business practices, selective scammers, Previously caught for having all product 50% underdosed, fights with others in the industry including a big one with Janoshik regarding poor testing and questionable request being made. Found a blind test results from someone on here testing the same brand primo 1 month before I got mines. Primo e-100 came back at EQ dosed at like 37-40mg/ml.

Ill quote the blind test below, but again its a blind test (they did a few companies primo's) so have to take it with a grain of salt.

The extreme drop makes me think they are using AI forsure, but again I wont know till I send them out. And for only a couple vials, id almost rather just not use them again. I re-did tests and continued utilizing it because I thought the same originally, maybe overdosed or im just sensitive to it, but as testing went on things just seemed more and more off. I think I would be estatic if it was severely underdosed primo with AI, compared to dealing with a long ester half life lol

I started the Primo on 9/14, so just over 2 weeks.

EQ would have prob taken a bit longer to lower e2 on its own from my research.

Im not pretending I know everything which is why im asking for advice from the experienced on here. I have however spent a lot of time digging into this. I dont like to just ask "help what do" but like to outline possible options and having you guys try to poke holes, educate or question me in regards is a great way for me to learn.

I didnt include my cbc/non-hormonal labs. But Hematocrit and rbc both elevated 1-2%. Re-running cbc to compare and make sure I wasnt a little dehydrated. My cbc and hematocrit actually improved when I upped my test dosage from baseline and 6 week follow up labs. EQ tends to have that effect as a blood maker.

 

[k710]

Here is some data from another member that seems pertinent to yours. Notice his standard test came back right where yours was but in reality his e2 was in range.

Kind of hard to be certain first time that you were having high e2 sides. Obviously is gyno was truly growing that needs to be dealt with.

I'm not sure why you are so concerned about running an ai. Seems like a recent fad to avoid them at all costs? Could easily have tossed in low dose aromisin a couple times a week and likely been fine.

View attachment 355523

Ive read pretty much every thread that mentions Primo, EQ, estrogen, and blood testing lol This one was interesting, but I tend to agree with what some users were saying about the difference in ref range and them almost being a ratio between standard and sensitive. They seem to change porportionaly until that last reading (which if I remember correctly was also attributed to other changes OP made).

Im all for data, but at some point you gotta ask "am I overcomplicating things?" I dont think regardless of your readings, you should be making changes that will move your e2 levels by 50% unless extreme case. Should aim for a gradual decrease which should allow time for you to re-test and confirm. If you thought your e2 was at 63, your not going to immediately try and cut it in half. Youd likely aim for 40-50 or dropping e2 10-15 points. Even if it was at 48.8 like sensitive e2 said, you wouldnt be in danger of crashing your e2 dropping it 35.Youd likely see the trend in your retesting and adjust to maintainance instead of lowering.

Ill likely just do both testing moving forward. And yes gyno was real on my right tiddy. Been using raloxifene and its gotten a ton better quickly. My prolactin baseline are high from ssri use and the estrogen load seems to love going right for the moobs lol

 

[Whistles77]

60mg of Primo shouldnt drastically change anyones e2 like what I experienced.

The extreme drop makes me think they are using AI forsure

On what basis? I've crushed mine using relatively low primo doses and now if i was running 300mg T, I'd probably choose a dose like yours with the intention of getting results like yours. Maybe a bit milder. A lot of your commentary seems to be asserting how various compounds affect you based on "your research" rather than experience.

Overdosed Primo is HIGHLY unlikely, not only because of market conditions, but because its an expensive raw product.

Although from earlier in 2025, i've some 15% and 12% overdosed primo from vendors here. Admittedly, that's less likely to happen with recent brews. Raws were still expensive back then. The overdosing was definitely a partial contributor to my crashes as i hadn't factored that in to what id actually taken.

Are you open to the possibility that Primo is real and has strong anti-estrogenic affects on you? You might be right that its EQ, or containing an AI, but i wouldn't rule out its not real primo without something more solid to go on.

I think your skepticism and learnings are wise though. Out of the great feedback so far. What are your next steps?

 

[k710]

Only way to know what you're getting is to test it. Add .3ml from each vial to a single vial, that adds up to ~1ml then send that for testing. You can use AB if you're on a budget and they charge 60$.

Primo and Mast will probably be back in stock for alot of sources in the next few months, which will give u time to stock up.

I havent looked at AB before. Jano is around $125 right? Was gonna stick with the OG when I did the testing, but right now im trying to be ready for when primo's start appearing again to stock up. I have mast p, but looking to add mast-e to the vault as well. I have some large expenses this month, but ill likely send it off the following month

 

[Photon]

I havent looked at AB before. Jano is around $125 right? Was gonna stick with the OG when I did the testing, but right now im trying to be ready for when primo's start appearing again to stock up. I have mast p, but looking to add mast-e to the vault as well. I have some large expenses this month, but ill likely send it off the following month

AB is $60, Jano $120

You keep testing costs low by buying in bulk.
Buy 10 vials of AAS.
Add .2ml from each vial to a single 2ml vial which costs close to nothing from Amazon. Send that 2ml vial in for testing, 60$.

 

[k710]

On what basis? I've crushed mine using relatively low primo doses and now if i was running 300mg T, I'd probably choose a dose like yours with the intention of getting results like yours. Maybe a bit milder. A lot of your commentary seems to be asserting how various compounds affect you based on "your research" rather than experience.


Although from earlier in 2025, i've some 15% and 12% overdosed primo from vendors here. Admittedly, that's less likely to happen with recent brews. Raws were still expensive back then. The overdosing was definitely a partial contributor to my crashes as i hadn't factored that in to what id actually taken.

Are you open to the possibility that Primo is real and has strong anti-estrogenic affects on you? You might be right that its EQ, or containing an AI, but i wouldn't rule out its not real primo without something more solid to go on.

I think your skepticism and learnings are wise though. Out of the great feedback so far. What are your next steps?

Am I open to thinking it real primo? Of course, I would be estatic if it was real primo, even though id have to drop the primo dose by 50% or bump the T to maintain healthy e2 levels. The problem comes from the AI being so aggressive that everyone Ive consulted seems to agree it came on too strong and too fast for EQ at such low dose. I dont rule it out and its why im willing to test it. If I was SURE it was one or the other, I wouldnt even test it. Just move on with my life. Not like my vendor is going to make things right or reimburse for testing.. its just for my own knowledge.

And my commentary is from research based because Im getting my first hands on experiences now. Ive read tons of journals and gotten tons of feedback from experienced members, but Im not nieve enough to pretend its all correct and the only way to go about things.


Heres that primo report I mentioned earlier I had come across.

Got some test results today. One is quite alarming, the supposed Primo from XT-Labs in Mexico.

- QSC Var - 80mg
- QSC Mast - 100mg
- QSC Test C - 250mg
- QSC Primo - 100mg
- Evolve Biolabs Var - 10mg
- Evolve Biolabs Primo - 100 mg
XT Labs Primo - NOT PRIMO

P.S my next steps for now are try and not make changes till I check in with coach for labwork review on Wednesday. I will be dropping said "primo" and allowing my test to raise e2. Debating between lose dose anastrozole for e2 control, but also have Mast-P on hand which I eventually wanted to include. Being a short ester, I was debating maybe giving it a couple weeks to see if it stopped my e2 from going higher or if it reduces it slightly and based on those results then include the low dose AI. Next cycle, will likely be primo unless Mast works well for me.

NPP was discussed for bulking, but with Prolactin a bit towards the higher side and estrogen going straight to my nips, I dont want to open up that can of worms till they are the only worms im worrying about

 

[k710]

AB is $60, Jano $120

You keep testing costs low by buying in bulk.
Buy 10 vials of AAS.
Add .2ml from each vial to a single 2ml vial which costs close to nothing from Amazon. Send that 2ml vial in for testing, 60$.

Never thought about combining a bit of all the sealed primo into one for testing. Thats very reasonable, considering the cost of the primo to begin with.

Is this a better approach than sending in a sealed vial? Assuming sealed vials are for blind testing vendor products for reimbursment as Ive seen all the "no vial = results useless" lol

 

[Photon]

Never thought about combining a bit of all the sealed primo into one for testing. Thats very reasonable, considering the cost of the primo to begin with.

Is this a better approach than sending in a sealed vial? Assuming sealed vials are for blind testing vendor products for reimbursment as Ive seen all the "no vial = results useless" lol

Some vendors require sealed vials for reimburse, majority (90%) dont.

 

[Whistles77]

Heres that primo report I mentioned earlier I had come across.

Gotcha. Yeah. I hadn't noticed about the primo report being mentioned. That's a massively useful data point that damns your vendor and would swing my opinion strongly towards your hypothesis. Your vendor has been caught selling this fake product before.

If its actually 40mg/ml EQ, then it does sound like there'd need to be something else in there to impact your e2.....and as the vendor was willing to try to palm of 40mg/ml EQ as Primo, then i wouldn't be surprised they'd do exactly what you said and added AI too. The vendor got caught lying in one of the worst possible ways. Everything you've posted is reasonable....and assuming worst case scenario seems the wisest move.

Personally, i'd assume anything from XT-labs is bunk and throw it all out (but of course testing is better if you have a lot) not sure how anyone would use 40mg/ml EQ anyway. Hope you didn't get too much of this....and hope you're doing ok on your low e2.

 

[Alert_Custard]

At this point you need to test that vial.
Finding out what it is would help you to know how you react to that compound, whichever it might be.

And last but not least, I am curious to know what is in that misterious vial. A mixture of stuff to make it feel like Primo? A bit like that Krokodyl drug that people made to get the same effects as heroin? Who knows.

 

[k710]

Gotcha. Yeah. I hadn't noticed about the primo report being mentioned. That's a massively useful data point that damns your vendor and would swing my opinion strongly towards your hypothesis. Your vendor has been caught selling this fake product before.

If its actually 40mg/ml EQ, then it does sound like there'd need to be something else in there to impact your e2.....and as the vendor was willing to try to palm of 40mg/ml EQ as Primo, then i wouldn't be surprised they'd do exactly what you said and added AI too. The vendor got caught lying in one of the worst possible ways. Everything you've posted is reasonable....and assuming worst case scenario seems the wisest move.

Personally, i'd assume anything from XT-labs is bunk and throw it all out (but of course testing is better if you have a lot) not sure how anyone would use 40mg/ml EQ anyway. Hope you didn't get too much of this....and hope you're doing ok on your low e2.

Yeah im using their test-c 300 that I think is just underdosed, but regardless not going to use anymore. Already have lab-tested test-e 250 to swap.
It was my first ever time ordering so got 8 vials and some arimidex, but of course it was overpriced. Lesson learned. Considering I was thinking about placing a wholesale order through xt directly.. the 8 overpriced vials seem like a blessing. Appreciate the kind words! I was honestly expecting to be feeling worse as time went on, but things have flattened a bit (at least I hope)

At this point you need to test that vial.
Finding out what it is would help you to know how you react to that compound, whichever it might be.

And last but not least, I am curious to know what is in that misterious vial. A mixture of stuff to make it feel like Primo? A bit like that Krokodyl drug that people made to get the same effects as heroin? Who knows.

Yeah mainly want it to fill in the blanks in my data, but also to warn others with hard facts and not just angry posting online. Plus once I have the results Ill be following up with naps to try and get XT off their platform since a lot of newcomers end up going through there.

 

[k710]

I started the Primo on 9/14, so just over 2 weeks.

Cant edit my original post, but for clarity I started "primo" 9/14, the date on the original post is for when labs were ran to check what the primo was doing.

 

[Tbaz192]

All this text and paragraphs, when the only logical common sense answer is to test it with jano. lol