You can use properly validated GCMS method to get quantitative purity.
mg of API by GCMS ÷ mg of raw
API is volatile and derivatization makes it even tighter.
Concern is whether HPLC giving us accurate purity for these raws.
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MESO-Rx
Anabolic Steroids
MESO "Specialized" Testing Group Fund
- Thread starter readalot
- Start date
mg of API by GCMS ÷ mg of raw
API is volatile and derivatization makes it even tighter.
Concern is whether HPLC giving us accurate purity for these raws.
dinfar1337
New Member
i know.
thats why we're seeking hplc - lcms as a middle ground.
because hplc-dad on its own is proving worthless on its own
Photon
Member
If we can get the mg, that's definitely possible.
I don't believe it's currently provided tho.
dinfar1337
New Member
i would 100% rather choose gcms than hplc-dad if i had to pick only one for raws.
think i said this couple of days ago
Correct, Jano's current GCMS setup is not validated quantitative method.
As I said, GCMS is light years ahead of HPLC-DAD in terms of chromatographic efficiency. Beautiful tight peaks. We are chasing shadows right now.
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We still need a raw purity. I don't know what it is on these raws.
Photon
Member
I believe I've asked before about using GCMS to cal purity.
I mistakenly mentioned mtren but i believe it's superdrol that uses GCMS to calc mg/ml.
Yes, derivatization a must for thermally labile shit.I believe I've asked before about using GCMS to cal purity.
I mistakenly mentioned mtren but i believe it's superdrol that uses GCMS to calc mg/ml.
Too much to ask for the UG. Anyway, good luck everyone.
Derivatization Methods in GC and GC/MS
The first part of this chapter presents the main objectives for performing derivatization of a sample to be analyzed by gas chromatography (GC) or gas chromatography/mass spectrometry (GC/MS). The derivatization is typically done to change the analyte properties for a better separation and also...
www.intechopen.com
dinfar1337
New Member
"QNMR to be sure, integrate every hydrogen, 500 bucks." - mr janoshik
"We are chasing shadows right now." - mr readalot
dinfar1337
New Member
anyways @Sampei is there more test results coming?
"Hey guys, here's 10k US, let's do this right." - mr dinfar1337
dinfar1337
New Member
i have 10 bucks"Hey guys, here's 10k, let's do this right." - mr dinfar1337
"my brother dinfar, here is 9990 dont worry we paid for it together!" - mr readalot
I think there is more NPP coming, from a member that would like to remain anonymous for his own security.
I have more raws incoming tho, so we can do more tests on other raws if it helps...
dinfar1337
New Member
i think its better to hold off on raw testing.
wait until the raw situation changes if it does. and when raws are flowing in more smoothly we will see if the labs can improve.
until now just hold onto the funds.
most people that can do 1+1=3 will be able to see the raw situation for now.
Best outcome from all of this work is if we could be confident in quantitative purity measurements for raws.
Are we picking up the correct purity for common AAS raws with standard HPLC method today?
The GCMS data above speaks for itself. Well done getting more GCMS data for raws.
Driada Britannica
Subscriber
How can we contribute to the fund? 
dinfar1337
New Member
Photon
Member
The oils are all brewed with the raw purity calculated by hplc, if we say that the raw purity is not calculated accurately, isn't that also saying the oil mgml is not accurate since they're supposedly matching?
dinfar1337
New Member
completely right!
hplc in mgml in oils and raws cant differentiate
in this example delta 6 test will show up as pure testosterone in hplc brewed im 99% sure off. just as it did in hplc raw testing
if it cant differentiate in raws it will never differentiate in oils
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