If 500mg of testosterone per week could keep building muscle forever, nobody would ever bother increasing the dose. We’d all just stay on 500mg and eventually walk around at 300kg of lean muscle. But biology doesn’t work like that.
Even with a perfect diet and training, your body eventually hits a plateau. Maybe it’s at 3 months, maybe 6, but it comes. This isn’t just “bro science” clinical studies (like Bhasin 1996) have already shown a dose dependent muscle gain with testosterone, but also that each dose reaches a ceiling. You gain the most in the early months, then the response flattens out.
Why? Because androgen receptors don’t respond infinitely. They downregulate over time, your body adapts, and the same dose stops producing the same gains. Combine that with biological limits on protein synthesis and recovery, and you can’t expect indefinite growth on the same dosage.
That’s why even professionals keep raising their doses. If 500mg worked forever, every pro bodybuilder would just sit at that and keep growing. But the reality is, after squeezing everything out of one dosage, the only way forward is either more food (already maxed), more training (already optimized), or more drugs.
Yes, adding GH changes the game by creating hyperplasia new muscle cells to grow so your 500mg of test works “better” for longer. But even there, growth eventually stalls. No one wakes up one day and starts blasting 2g of test, 1g tren, 10iu GH, and insulin. It’s always the same process: you grow, you plateau, and the only way to push past that plateau once training and diet are optimized is through progressive increases in the dose.