MESO-Rx
Anabolic Steroids
Giant Semaglutide Thread (and other GLP-1 / GIP agonists)
- Thread starter Doodle
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ineffectual
Member
Any specific foods setting the hunger off or just any kind of food? I'm have been going through this myself but I'm at a weight I'm happy with,just don't like the fleshy gut. I feel like I'm eating like before but overall my weight is staying steady. I've noticed carbs, sugar really sets me off. I will kinda just be shoving food in my mouth with the thought "Oh no, put this shit down you are full stop" It's almost what I did before sema. Just no where near the Same amount and type of trash I used to shovel in my mouth.
I wake up in the morning feeling satisfied and If I don't eat anything I'm fine so I guess a fast.
BadandyB
New Member
For me, the food doesn't matter. After I wake up I can go until mid-afternoon before eating if I really want to, but once I start eating I want to eat until bedtime.
ineffectual
Member
Was it like that before as well? I'm just very curious.
BadandyB
New Member
It was like that before sema for me. Disappeared with sema. Took about 6 months after sema for it to return. Now just started back on sema.
bananafeet
Member
Mazdutide update:
On 5mg once a week now. It is lasting all week.
My stomach is pretty much on lockdown 24/7. Reflux is terrible lol
Anyway down to 106.8kg
One benifit is I'm less fatigued and when I'm at home I literally forget to eat. I can't eat breakfast really.
Pretty good compound. I rate it. I'd say it's half as powerful as semaglutide dosing wise.
On 5mg once a week now. It is lasting all week.
My stomach is pretty much on lockdown 24/7. Reflux is terrible lol
Anyway down to 106.8kg
One benifit is I'm less fatigued and when I'm at home I literally forget to eat. I can't eat breakfast really.
Pretty good compound. I rate it. I'd say it's half as powerful as semaglutide dosing wise.
Ghoul
Member
We continue to learn more about what makes GLPs more or less effective for certain individuals.
Coincidentally, this just released study may shed some light on what's been discussed here lately.
This is the first time I've seen GLP's effect on "Externally triggered" vs "Emotional" eating measured.
www.frontiersin.org
Coincidentally, this just released study may shed some light on what's been discussed here lately.
This is the first time I've seen GLP's effect on "Externally triggered" vs "Emotional" eating measured.
Frontiers | Association between eating behavior patterns and the therapeutic efficacy of GLP-1 receptor agonists in individuals with type 2 diabetes: a multicenter prospective observational study
BackgroundGlucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used to improve glycemic control and induce weight loss in individuals with type 2 ...
www.frontiersin.org
ineffectual
Member
that sucks about the emotional eating. I know that's what I tend to do.We continue to learn more about what makes GLPs more or less effective for certain individuals.
Coincidentally, this just released study may shed some light on what's been discussed here lately.
This is the first time I've seen GLP's effect on "Externally triggered" vs "Emotional" eating measured.
View attachment 349215
Frontiers | Association between eating behavior patterns and the therapeutic efficacy of GLP-1 receptor agonists in individuals with type 2 diabetes: a multicenter prospective observational study
BackgroundGlucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used to improve glycemic control and induce weight loss in individuals with type 2 ...
Ghoul
Member
I think high enough dose of any GLP, but especially Sema, will put a stop to overeating by making it physically impossible. Sema doesn't care about your emotions, it's brutal.
Liter O' Test
Member
Ive had one cheat meal since I started tirz,
7 days off nicotine completely.
I'm up to 500g+ carbs,
doing 3-4 tablespoon physllium husk.
if it wasn't for getting hiccups half the time after I eat, and the BG readings, I would think I wasn't on anything.
Oh and not having any energy "crashes" from larger meals. Thats actually probably the biggest upside people probably forget to talk about
7 days off nicotine completely.
I'm up to 500g+ carbs,
doing 3-4 tablespoon physllium husk.
if it wasn't for getting hiccups half the time after I eat, and the BG readings, I would think I wasn't on anything.
Oh and not having any energy "crashes" from larger meals. Thats actually probably the biggest upside people probably forget to talk about
for me it's like one thing leads to another. Like I usually put off eating until I have to train, or on reat days I might even do OMAD since I find fasting pretty easy.
But once I start I get even hungrier. Like I'll eat vegetables, then meats, then eggs or yogurt with fruit and then I'll be craving all sorts of shit. (like that sort of craving that dows not subside even after a few hours)
I don't think it's even emotional, it's like a disconnection from my brain to my gut, because Tirzepatide 5mg completely fixed it at first, then after loosing weight it came back. went to 10mg and mostly fixed again,lost some more and it's back.
I was looking at Mazdutide as well and the glucagon agonism seems very attractive. Might consider to stack it. I'd like to get the benefit of the glucagon part.
I could also switch to Reta completely but the increased heart rate and less potent appetite suppression of Reta kinda puts me off it. I know Maz slightly increases heart rate too but it's only like 3-8bpm in the studies and my resting heart rate is like 55bpm so not a huge concern
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Absolutely. With Tirz even if I binge eat (which by now I can do with no GI issues, for the best or for the worse) I don't crash. just consistant regular energy
BrunoES
Member
Tirzepatide update:
48h post first 2.5mg shot
72h post first 2.5mg shot
48h post first 2.5mg shot
- Fell 450kcal short of yesterday's kcal target, but could have eaten if I wanted, just didn't want the volume and risk today's wellbeing
- Mild night headache
- Woke up twice to poop, then some diarrhea in the morning
- Burps gone, stomach ache still here
- 3lbs lighter today, probably from all the poop lol
- Still can't distinguish if its already an appetite suppression or just GI distress. Meaning: not hungry, but can eat since I know my macros
- Overall feeling much better today, I will know it's really working when I can't finish my food even if I try to, then I will switch to higher calorie density foods
72h post first 2.5mg shot
- Last meal at 5PM, by 8PM until around 2AM was consistently waking up to burp, and passing gas
- Woke up at 5AM, and despite the night being worse (wasn't bad, slept well, just woke up many times) than the night before, I was feeling better than yesterday
- By 6AM had no more bloating, gas or burps, after going to the toilet multiple times, I am all empty now lol
- Was 350kcal short from yesterday's target, and believe may be able to get all my calories in today.
- Was another 3lbs lighter today. I hope this is just because of the empty gastrointestinal tract and dehydration. My target calories are 3700 for maintenance, so this two lower calories days should not have a big impact. I also kept sodium high (as always), up to 10g/day (sodium, not salt). My goal here is not to lose weight, just to turn eating into a job not a hobby.
- Waiting to get to a place where I don’t have any GI distress to accurately tell if my appetite is indeed lower
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BrunoES
Member
How does hedonic eating fits into these descriptions? I would guess the latter, but not sure.We continue to learn more about what makes GLPs more or less effective for certain individuals.
Coincidentally, this just released study may shed some light on what's been discussed here lately.
This is the first time I've seen GLP's effect on "Externally triggered" vs "Emotional" eating measured.
View attachment 349215
Frontiers | Association between eating behavior patterns and the therapeutic efficacy of GLP-1 receptor agonists in individuals with type 2 diabetes: a multicenter prospective observational study
BackgroundGlucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used to improve glycemic control and induce weight loss in individuals with type 2 ...
Ghoul
Member
It's both. Often externally triggered, emotionally soothing.
Superchicken
Member
That T level is terrible, and hypogonadal even by shitty medical standards. I’d start trt asap. My husband’s was low and it combined with low dose tirz + gym gave him full body recomp in about 9 mos. Not ideal, but taking T without any training has been shown to increase muscle mass.
Earthworm Jim
Member
I love that feeling of hurting after eating something sugary on reta. It's like, "YES! ITS WORKING!!"
Earthworm Jim
Member
I went thru this mental craving also. It was because my brain was used to burning sugar and starch for fuel. So I settled it in my mind that I would be uncomfortable for a few days as I forced my brain to switch to burning fat. This was before I started using GLP-1. What I found what I no longer ate limitlessly and my taste for bagels switched to craving red meat. At this point, for me, it's just a matter of not bringing home foods that are going to reteach my brain to rely on sugar instead of my fat stores for fuel.
Also I commanded my body and brain to start burning fat instead of sugar in the name of Jesus. I think hearing myself command that out loud, and having faith, helped tremendously. But my first step was settling it in my mind that there would be a few days of discomfort as my brain switched fuel sources
Ghoul
Member
Yes, appetite shift from carbs to protein was dramatic for me as well.
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