AI Comparison: Aromasin vs. Arimidex

Type-IIx

Member
This is very useful.

Related, do you know if we have an understanding of how these drugs compare when it comes to the other side-effects, such as adiposity and lipids, as well as what percentage can be attributed to the AI vs. simply having low E2 levels? I am guessing that the Finkelstein study you reference probably suppressed estrogen levels to very low levels, rather than something more balanced that would be considered in range.
 
This is very useful.

Related, do you know if we have an understanding of how these drugs compare when it comes to the other side-effects, such as adiposity and lipids, as well as what percentage can be attributed to the AI vs. simply having low E2 levels? I am guessing that the Finkelstein study you reference probably suppressed estrogen levels to very low levels, rather than something more balanced that would be considered in range.
Your guess is incorrect! You can look up the study, it's probably open access.

It suppressed levels totally to 0 in one group (the unlucky one) in each cohort (2 cohorts), and then gave graded doses, like 2.5 mg weekly testosterone transdermally, 5 mg TD, up to 10 mg TD weekly which is supraphysiologic to all the other groups, so only two of the groups had "low" E2 levels.

All our E2 comes from aromatase, anyway, as men. It's mostly testosterone/E2 but also some from the neurosteroid/adrenal pool like DHEA and such.

Yes we have that understanding, to your questions.
 
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