GH works better with higher estrogen?

Lol, I never said a dropped vial was useless.

I said you claimed it would damage it. Jesus Christ you are idiotic.

I want to broker a truce. The forum needs you both and I stupidly fought with Spaceman for far too long after he got me good with the clown gif. Well done Spaceman.

So only way to settle this is ghoul you donate on the next group testing project. Okay?

I know Spaceman will and I am down. After that, all shit talking can continue but we all gotta pay our way into the shit talking club. LFG!!

Ariana Grande Singing GIF by The Voice
 
I want to broker a truce. The forum needs you both and I stupidly fought with Spaceman for far too long after he got me good with the clown gif. Well done Spaceman.

So only way to settle this is ghoul you donate on the next group testing project. Okay?

I know Spaceman will and I am down. After that, all shit talking can continue but we all gotta pay our way into the shit talking club. LFG!!

Ariana Grande Singing GIF by The Voice

There is no mic drop here.

The guy spends his whole time here spreading information way out of his league.

He combines information with no base or clinical knowledge. Only to comes to the conclusion through chat GPT.

His conclusions he does come to is complete shit.


He insults Meso QC when he does no testing himself, and he has very ltitle respect of most of the vets here that know he speaks without even any experience.

There is a reason why he wont contribute shit to his NMR testing he has discussed.
 
Ghoul is completely correct in this case no matter what bloodwork is provided or google AI sources. So tired of people using serum igf-1 as if it's a useful biomarker at all.

Estrogen increases SOCS-2/3 expression, which would further inhibit the GHR-JAK2-STAT5 pathway. Not to mention it increases IGFBP-1.

Technically, lower estrogen always equates to greater GH to IGF-1 conversion, so it should be kept lower on exogenous GH. But I would also agree that we should not bring it so low as to impair insulin sensitivity.

But if people want to follow youtubers and raise their estrogen as much as possible and eat like shit so they can have a higher serum igf-1, be my guest.
 
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The worst?
Yes, based on the fact you can’t trust him. He will never accept when he is wrong, saved face is everything as this forum probably is everything he got.

The worst people are the ones who think they know everything about everything just to post some garbage information they find online.

As an example if he had any experience he would know more test = more e2 = more gh to igf conversion (ofc there is a limit how much estrogen you can benefit from and handle) Why he don’t know this is because he has no real life experience and are new to the game and still talk like he knows everything.

Comeplete shit head.
 
Ghoul is completely correct in this case no matter what bloodwork is provided or google AI sources. So tired of people using serum igf-1 as if it's a useful biomarker at all.

Estrogen suppresses SOCS-2/3 expression, which would further inhibit the GHR-JAK2-STAT5 pathway. Not to mention it increases IGFBP-1.

Technically, lower estrogen always equates to greater GH to IGF-1 conversion, so it should be kept lower on exogenous GH. But I would also agree that we should not bring it so low as to impair insulin sensitivity.

But if people want to follow youtubers and raise their estrogen as much as possible and eat like shit so they can have a higher serum igf-1, be my guest.
Wrong.

Thats also how the IFBB pro’s run their cycles. John Jewett teaches this in his j3university. They run up e2 as high as they can handle without side effects to get the most out of their gh. But hey better listen to you or Ghoul and you ”science”

You gotta love these 170lbs internet gurus.
 
Wrong.

Thats also how the IFBB pro’s run their cycles. John Jewett teaches this in his j3university. They run up e2 as high as they can handle without side effects to get the most out of their gh. But hey better listen to you or Ghoul and you ”science”

You gotta love these 170lbs internet gurus.
Wrap it up boys, the pros do it. You got me guy.

If only one day I could be accepted to the highly sought and accredited “j3university.”

Like I said bro keep doing it, I hope it goes well. You can’t actually argue my points directly because it’s not possible.
 
Wrap it up boys, the pros do it. You got me guy.

If only one day I could be accepted to the highly sought and accredited “j3university.”

Like I said bro keep doing it, I hope it goes well. You can’t actually argue my points directly because it’s not possible.
You don’t ask a poor man how to get rich.
You don’t ask a skinny kid how to build muscle.

It is what it is. You are 100% wrong but hey believe whatever you want.
 
You don’t ask a poor man how to get rich.
You don’t ask a skinny kid how to build muscle.

It is what it is. You are 100% wrong but hey believe whatever you want.
Sorry but you are wrong about how the "IFBB pros" are because you lost everyone there, IFBB pros cycles are out there nowadays, not that much of a secret, and you will be surprised to find guys running boldenone, primobolan and hefty doses of AI on top, during an off season cycle...
 
You are 100% wrong but hey believe whatever you want.

Sorry but you are wrong about how the "IFBB pros" are because you lost everyone there, IFBB pros cycles are out there nowadays, not that much of a secret, and you will be surprised to find guys running boldenone, primobolan and hefty doses of AI on top, during an off season cycle...
They are on 1+ gram of test ofc they need to lower their e2. There is a limit where more e2 won’t increase gh to igf conversion and thats individual.

Once they know that limit they want to stay there and need to control it, can be 30, 60, 100 e2 and some get gyno easier than others.
 
Sorry but you are wrong about how the "IFBB pros" are because you lost everyone there, IFBB pros cycles are out there nowadays, not that much of a secret, and you will be surprised to find guys running boldenone, primobolan and hefty doses of AI on top, during an off season cycle...
Can you share please ? I would be surprised to see an IFBB off season protocol with high dose of primo and/or boldebone with "hefty dose of AI on top". Be it with 1g of test or 5g of test.

Off season Protocol of john jewett leaked and it was :

1g9 test
1g7 mast
170 TA
10 Iu HGH

Dont remember if there was any slin or reta.
 
Can you share please ? I would be surprised to see an IFBB off season protocol with high dose of primo and/or boldebone with "hefty dose of AI on top". Be it with 1g of test or 5g of test.

Off season Protocol of john jewett leaked and it was :

1g9 test
1g7 mast
170 TA
10 Iu HGH

Dont remember if there was any slin or reta.
John is a huge advocate of mast because it does not lower e2. If high e2 equals less gh to igf conversion i guess his 10iu wouldn’t benefit him right?

Doesn’t make any sense at all.
 
You don’t ask a poor man how to get rich.
You don’t ask a skinny kid how to build muscle.

It is what it is. You are 100% wrong but hey believe whatever you want.

To be fair, there are people who have a lot of experience and training and don't have to be big. I hate the refer to a influencer but anatoly is one. He's not a big guy.

The only experience that ghoul has is as a patient for being baseline unhealthy.

But we all know igf1 is not the end-all be all for response to HGH. But people can keep throwing out information that they read online.

People put too much value on Google when he really has a little to no experience. He doesn't do any testing, and he has been bashing people who have been using janoshik.


He tries to justify why he doesn't do testing. And somehow he talks like he's rich.

But what we do know is that he's prescribed Max dose of tirzepatide.
 
Yes, based on the fact you can’t trust him. He will never accept when he is wrong, saved face is everything as this forum probably is everything he got.
Why make that assumption?

I agree with the admitting you are wrong part. People should do that. It is how we all learn and get better.

Just look at this thread. It is wild.
 
Why make that assumption?

I agree with the admitting you are wrong part. People should do that. It is how we all learn and get better.

Just look at this thread. It is wild.
I make that assumption by the reason almost every thread i read he is there telling everyone what is correct and what is wrong.

I’ve been arguing here way to long that my wife asking wtf im doing, so how can someone have a life outside of the forum being as active all day every day as him.
 
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