MESO-Rx Sponsor Primal Pharma - US Domestic

[readalot]

Are you sure you haven’t started Tren already? You have been in rare form my friend.

100 mg/week Test Cyp right now plus recently started 5 mg/d finasteride and some tadalafil. And the alfuzosin. You are probably on your something, I may not be right.

 

[verylargeshoes]

Maybe tren not a great idea for me after all.

Maybe he’s born with it.
Maybe it’s trenbollone.

 

[BamaCrazy]

100 mg/week Test Cyp right now plus recently started 5 mg/d finasteride and some tadalafil. And the alfuzosin. You are probably on your something, I may not be right.

Well, whatever you are doing it’s working. The old Readalot couldn’t rally the troops for testing if his life depended on it. Now you got members who will never use Tren throwing money at you.

 

[sionnach]

Are those results from Quest? My E2 was 295 at the end of June on 150mg Test C only. But 22 one month later at LabCorp. And I didn’t take anything to lower my E2.

We often forget estrogen/estradiol fluctuates just as much as test (if you have a woman in your life you know it's likely moreso) and can do so in response to many variables including diet, sleep and stress.



One high result one time is not a worry, nor reason to make huge adjustments. We need repeated data points over time. Like I said earlier, 104 isn't that high. The real question in response to a higher than expected result should be, "Are you having symptoms?".

 

[readalot]

Well, whatever you are doing it’s working. The old Readalot couldn’t rally the troops for testing if his life depended on it. Now you got members who will never use Tren throwing money at you.

Live and learn. We are actually stalled out right now. I am concerned I could be doing something better to keep the needle moving. Any suggestions to keep the momentum going? You always have such a level head about these matters.

 

[BamaCrazy]

We often forget estrogen/estradiol fluctuates just as much as test (if you have a woman in your life you know it's likely moreso) and can do so in response to many variables including diet, sleep and stress.

View attachment 342500

One high result one time is not a worry, nor reason to make huge adjustments. We need repeated data points over time. Like I said earlier, 104 isn't that high. The real question in response to a higher than expected result should be, "Are you having symptoms?".

I had never felt better with E2 at 295. But a fluctuation of 273 is wild.

 

[BigDadd7]

Here’s a test to see if your estrogen is too high.. How much rage do you feel when I say “I think you need to calm down, babe.” On a scale of 1 to divorce.

I'm taking the house

 

[readalot]

My E2 was 295 at the end of June on 150mg Test C only. But 22 one month later at LabCorp. And I didn’t take anything to lower my E2.

pg/ml?

Standard ECLIA method?

 

[BamaCrazy]

Live and learn. We are actually stalled out right now. I am concerned I could be doing something better to keep the needle moving. Any suggestions to keep the momentum going? You always have such a level head about these matters.

I’m going to donate today. I’ve been slammed at work. But you can extend the timeline to donate and do another funding drive, or look at how you can reduce cost on this first round of testing.

 

[BamaCrazy]

pg/ml?

Standard ECLIA method?

 

[readalot]

I’m going to donate today. I’ve been slammed at work. But you can extend the timeline to donate and do another funding drive, or look at how you can reduce cost on this first round of testing.

There is no deadline. That was just a little marketing promo I was doing in the last day.

The money has been spent on this first round. That project has already been paid for. I hope that was clear enough. All that remains is how much I ask for reimbursement which i am noodling on.

Thanks for feedback.

 

[readalot]

View attachment 342502

What was your TT/FT?

 

[BamaCrazy]

What was your TT/FT?

 

[sionnach]

I had never felt better with E2 at 295. But a fluctuation of 273 is wild.

295 is the outlier. The fluctuation means your body recognized a problem and took care of it. I wouldn't even bother to dig into what caused the jump unless it happens again. But I would get a repeat lab every 5-6 weeks until I was sure it wasn't going to.

 

[readalot]

We often forget estrogen/estradiol fluctuates just as much as test (if you have a woman in your life you know it's likely moreso) and can do so in response to many variables including diet, sleep and stress.

View attachment 342500

One high result one time is not a worry, nor reason to make huge adjustments. We need repeated data points over time. Like I said earlier, 104 isn't that high. The real question in response to a higher than expected result should be, "Are you having symptoms?".

That would depend on your injection frequency which he did not provide.

An E2 of 300 pg/ml on 150 mg/week of Test C is almost nonsensical. I am going to go with testing error.

 

[sionnach]

View attachment 342504

That FT on 150/wk tho. What else were you taking?

 

[readalot]

View attachment 342504

Very reasonable TT/FT. Right tests. Props.

Someone f'ed up the LCMS for E2 at Quest. They should have repeated it.

 

[verylargeshoes]

That would depend on your injection frequency which he did not provide.

An E2 of 300 pg/ml on 150 mg/week of Test C is almost nonsensical. I am going to go with testing error.

I was thinking the same thing. I mean, I know we all aromatize differently, but Bama would have to be a morbidly obese hermaphrodite in the midst of ovulation to hit that E2 level with the dose taken and TT numbers.

 

[readalot]

That FT on 150/wk tho. What else were you taking?

Very reasonable response to that dose. If he tells us his injection frequently and when he pulled blood work we can even get more accurate.

R

Post in thread 'Tool to Assess your TT dose response --Percentile Curves'

Oct 5, 2023

Linear version of graph....
You can use regression equations from Bi 2018 study to get low, mean, high estimates for TT level vs weekly equivalent dose.



Here’s the mean TT level (ng/dl) for 70. mg/week of Test Cypionate (see equations on chart below):

2.5 percentile response = 360
50 percentile response = 630
97.5 percentile response = 1200

Don't forget to use this table to convert your blood work result (trough) on given dosing protocol to mean:


Table: conversion between peak/trough/mean for first order absorption/elimination PK model assuming 4.5 day elimination...

• readalot

• 
• 

 

[sionnach]

Very reasonable TT/FT. Right tests. Props.

Someone f'ed up the LCMS for E2 at Quest. They should have repeated it.

I was thinking the same thing. I mean, I know we all aromatize differently, but Bama would have to be a morbidly obese hermaphrodite in the midst of ovulation to hit that E2 level with the dose taken and TT numbers.

Probably testing error. It is Quest, they only have 1 LC/MS lab for west coast. 295's not impossible on that dose, but factoring in TT/FT it is unlikely.