Random Collection of Questions

1. Is it correct that Mast E will only raise Total T levels on a LC/MS (aka sensitive) blood test and not in a non-sensitive test?

This makes no sense. Drostanolone is a completely different molecule, it will absolutely not show up as testosterone, and unless you supplement with testosterone, your levels will over time drop lower and lower. Your understanding of these things is on a very low level, and you need more book reading to get basics straight.
 
Doesn't look like it from your other thread, "long term bulk", pages of answers, yet you only replied to whoever gave you a "yes man" answer.

Edit: of course you did reply to more people, but you only apprehended the message of whoever agrees with your original views.
I replied to the majority of the posts on that thread… but I see I missed the following one from you:

(It’s long so will reply later today once I’m off work - wasn’t intentional by any means)

“All of this is too complicated and sounds like textbook Todd Lee youtube script.

It is difficult to sell old basic recipes, so what youtube content creators do is try to be authentic with original content, regardless if it is better than the old basic proven recipes.

You are talking about not using an AI and then adding masteron, or even worse, DHB. Why not research which AIs you can use and compare with masteron?

Let me give you a short cut to what you will figure out in a few years and tons of money spent:

Arimidex affects lipids just a bit, barely noticeable, and even less if you figure out your minimum effective dose. Exemestane affects them even less - personally I barely got changes in lipids from test only with exemestane cycles. Masteron, however, will crush your lipids, and from my experience and shared experience with real life friends who have used AAS for years, dosages in the ~300-500mg range don't seem to build any muscle, but give nice cosmetic benefits which you have to be lean to notice. It also gives a CNS boost which all AAS do as you go up in total milligrams.

To sum it up, masteron will wreck your lipids while exemestane will barely make a difference. Masteron will also cost exorbitantly more than exemestane. Testosterone is the best bet for mass and strength, while also the safest option for health. So substituting testosterone with masteron because you won't need an AI just makes no sense.

I also feel compelled to tell you that both masteron and DHB are not for beginners, they are for specific purposes at specific times, none which you have mentioned a need for.”
 
1. Is it correct that Mast E will only raise Total T levels on a LC/MS (aka sensitive) blood test and not in a non-sensitive test?

This makes no sense. Drostanolone is a completely different molecule, it will absolutely not show up as testosterone, and unless you supplement with testosterone, your levels will over time drop lower and lower. Your understanding of these things is on a very low level, and you need more book reading to get basics straight.
Great, I didn’t think it would show up but I saw a couple of other comments saying that MastE would show up as higher total t on a LC/MS (sensitive test) but not on a non sensitive test. What you’re saying about it being a different molecule and therefore wouldn’t show up on a testosterone test makes sense. Thanks
 
2. Does Mast E impact free T?

Drostanoline will lower SHBG. IIRC every single AAS will lower SHBG, even testosterone at higher dosages. Lower SHBG means less bound testosterone, which means higher free testosterone.

However! You can't just have these facts and then yell "I know!", you will always see different results in different peoples bodies. I for example naturally had lower SHBG, whatever compound I use will make it drop just a little but never in the low single digits, and going on a test dose that gives me normal range test does not help make it go high, maybe get up to 12 nmol/L, and down to 9 nmol/L after a cycle.

This is why it is not helpful to get these "facts" straight from a forum or YouTube. You need to do science on yourself and collect your facts, not someone else's facts, on what works and how it works.
 
2. Does Mast E impact free T?

Drostanoline will lower SHBG. IIRC every single AAS will lower SHBG, even testosterone at higher dosages. Lower SHBG means less bound testosterone, which means higher free testosterone.

However! You can't just have these facts and then yell "I know!", you will always see different results in different peoples bodies. I for example naturally had lower SHBG, whatever compound I use will make it drop just a little but never in the low single digits, and going on a test dose that gives me normal range test does not help make it go high, maybe get up to 12 nmol/L, and down to 9 nmol/L after a cycle.

This is why it is not helpful to get these "facts" straight from a forum or YouTube. You need to do science on yourself and collect your facts, not someone else's facts, on what works and how it works.
Thanks! This is very helpful - I was mainly asking as I was trying to figure out if this may impact the bloodwork that my primary care physician sees and therefore impact my trt prescription.
 
Thanks! This is very helpful - I was mainly asking as I was trying to figure out if this may impact the bloodwork that my primary care physician sees and therefore impact my trt prescription.

6. I heard Mast E can hurt lipids? Is it mainly decreasing HDL or can it also raise LDL? Is it fair to ignore HDL/LDL and focus on ApoB and as long as it’s under 1 to assume all is good?

Best is to google for studies on what blood markers various compounds affect. If you are lazy then use chatGPT to summarize studies. You have to research these compounds for yourself though, after you have google or ChatGPT summarize their effects, look up the studies and see how they work. Masteron is not something you take just to solve one issue (water weight), it is a drug with it's own side effects. Whether it will help reduce the water weight is subjective, try and see how it affects you, but generally yes, it is a bodybuilding drug used for cosmetic purposes (hardening).

See the contradictions here with agreeing to giving you the yes to take masteron. You are clinging on to one experts "certified fact ®" to only rely on ApoB levels and assume all is good. You are trying to juggle collected facts and making things increasingly complicated, yet you haven't researched how masteron works. Then you wonder why the responses in your other thread were so negative? Because everyone saw through your low level of understanding on these compounds yet persist on using them to solve another problem caused by another compound.

3. I carry a bit of water weight due to my high e2 on Test. Will adding Mast E take some of that water weight off of me (I assume yes)

How do you know you gained water weight from estrogen? Might just be testosterone itself. Again, more compounds creating more problems to solve problems created by other compounds. When it all goes to shit, you don't know which lever to pull.

4. My bloodwork showed 98 e2 @ 1333 Total T and at this level I have zero sides outside carrying a little additional water weight, so I assume not a huge deal?

Too much of anything for too long will have repercussions. For one, you will accumulate fat easier and in particular areas with high estrogen.

7. I don’t have mbp in the family, but I’m wondering at what DHT:e2 ratio that I should start to be concerned?

This is way too subjective. I would never blindly trust a metric like this because of some reasoning on how the receptors are affected by the hormones. It is an oversimplification and you might up losing hair simply because you added a DHT derivative like masteron.

9. If someone takes more anabolic load then they need to grow then does that mean they will just continue to grow until they have maximized that anabolic load, or are they essentially wasting it since it someone desensitizes them to it sooner than they needed?

What's "anabolic load"? Sounds like food, training and sleep are factors in anabolic load.be. Generally you desensitize to a dose after a certain amount of time regardless of how high the dose is. More milligrams does not equal more gains past a certain point. These questions are answered by your own experiences though, asking for someone else's data will never guarantee what your own outcome will be.

10. Does DHB have potential impacts on blood markers outside of liver/kidney values? Such as RBC/HCT, HDL, LDL, etc?

Of course, as do all AAS. ALL! Research this for yourself, these questions are too easily answered with simple google searches. Some people are feeding you bullshit under the guise of clearing your head from bullshit and here you are asking about using one of the harshest compounds without knowing basics.
 
Thanks! This is very helpful - I was mainly asking as I was trying to figure out if this may impact the bloodwork that my primary care physician sees and therefore impact my trt prescription.
If your doctor is watching your blood markers, you won't be able to run your extra compounds unless you have enough time to recover before next bloods. They're doctors, they know, even if they only ordered hormone panels and blood counts, they would figure it out.
 
Start feeding ;-) fuck me for asking questions on an online forum
I’d gladly do that until you learn to behave.

You could search in the hundreds of threads and in case you wanted something more specific you could just simply ask there. As you see no one is willing to waste half an hour to answer your extended list of questions. A forum is a place to exchange knowledge, information and personal opinions and so far you i ain’t seen you bringing anything to the table besides questions upon questions. Send me 100 bucks and I’ll answer, after I finish with the other thing you asked first. ;-)
 
My 2 cents.
Mast shouldn't affect Total T as far as I understand, could be some MOA I am not up on though. Will lower SHBG allowing for more free test. I'm a fan of bioavailable test versus free but it's often an add on $$$.
That's high for me for E2 id be a mess. So interesting how people are all so different on that.
All peds for the most part impact lipids. APO B is certainly something you want to keep an eye on. Above 1.0 isn't great IMO. Red yeast Rice and citrus bergamot consider taking. Ap a is a genetic test I think anyone with peds should take.
Drink lots of water your resting HR seems high, what's your Crit and rbc? Go donate blood , works like a charm for me.
DHB I stay away from. So have no thoughts it experience to share.
Hope that helps in some small way.
Cheers
 
2. Does Mast E impact free T?

Drostanoline will lower SHBG. IIRC every single AAS will lower SHBG, even testosterone at higher dosages. Lower SHBG means less bound testosterone, which means higher free testosterone.

However! You can't just have these facts and then yell "I know!", you will always see different results in different peoples bodies. I for example naturally had lower SHBG, whatever compound I use will make it drop just a little but never in the low single digits, and going on a test dose that gives me normal range test does not help make it go high, maybe get up to 12 nmol/L, and down to 9 nmol/L after a cycle.

This is why it is not helpful to get these "facts" straight from a forum or YouTube. You need to do science on yourself and collect your facts, not someone else's facts, on what works and how it works.
This thread and links therein covers the myth that "lowering SHBG frees up more T".


%FT (FT/TT x 100%) goes up but absolute FT (ng/dl) will not.

Hope it helps folks. Exhaustive links to other posts and threads over the years. Even wrote out the transient mass balance to new stable state.
 
A few questions that I’ve been hanging onto (thanks in advance!):

1. Is it correct that Mast E will only raise Total T levels on a LC/MS (aka sensitive) blood test and not in a non-sensitive test?

2. Does Mast E impact free T?

3. I carry a bit of water weight due to my high e2 on Test. Will adding Mast E take some of that water weight off of me (I assume yes)

4. My bloodwork showed 98 e2 @ 1333 Total T and at this level I have zero sides outside carrying a little additional water weight, so I assume not a huge deal?

5. After the above blood test, I increased my Test C dose by 5mg a day and after two weeks I’m finally starting to get some spicy nips for 1-2 hours every other night or so… do I need to worry about gyno at this point (should I roll back to last dose and pop 1/4 AI) or is it safe for me to go another few weeks to see if it subsides on its own?

6. I heard Mast E can hurt lipids? Is it mainly decreasing HDL or can it also raise LDL? Is it fair to ignore HDL/LDL and focus on ApoB and as long as it’s under 1 to assume all is good?

7. I don’t have mbp in the family, but I’m wondering at what DHT:e2 ratio that I should start to be concerned?

8. What resting heart rate is assume safe? (I’m at around an 85)

9. If someone takes more anabolic load then they need to grow then does that mean they will just continue to grow until they have maximized that anabolic load, or are they essentially wasting it since it someone desensitizes them to it sooner than they needed?

10. Does DHB have potential impacts on blood markers outside of liver/kidney values? Such as RBC/HCT, HDL, LDL, etc?
While we’re spoonfeeding you, is there anything else you need? Fold your clothes, pick up your legos, maybe wipe your tushy?
 
This thread and links therein covers the myth that "lowering SHBG frees up more T".


%FT (FT/TT x 100%) goes up but absolute FT (ng/dl) will not.

Hope it helps folks. Exhaustive links to other posts and threads over the years. Even wrote out the transient mass balance to new stable state.
Beautiful graph of the behavior when you drop your SHBG quickly with say oxandrolone. This case assumes you are taking exogenous T.

 
This thread and links therein covers the myth that "lowering SHBG frees up more T".


%FT (FT/TT x 100%) goes up but absolute FT (ng/dl) will not.

Hope it helps folks. Exhaustive links to other posts and threads over the years. Even wrote out the transient mass balance to new stable state.
Thanks, I learned something new. I haven't noticed this on myself and would be baffled if I suddenly saw a lower total test when my exogenous test dose remained constant, but my SHBG never fluctuates so much. Seems I have to do some book reading myself, because I never came across this.
 
This thread and links therein covers the myth that "lowering SHBG frees up more T".


%FT (FT/TT x 100%) goes up but absolute FT (ng/dl) will not.

Hope it helps folks. Exhaustive links to other posts and threads over the years. Even wrote out the transient mass balance to new stable state.
I'm happy to post my bloods from a week ago so and have someone explain how my SHBG is 18, and my total test is 197 and my Bioavailable test is 187, I'm Canadian if those numbers look weird , if Mast E is not driving my shbg into the teens? What is? i'm on memory here for those numbers could be a hair off but that's the piece. Not arguing just saying I'm on test and mast....
 
Thanks, I learned something new. I haven't noticed this on myself and would be baffled if I suddenly saw a lower total test when my exogenous test dose remained constant, but my SHBG never fluctuates so much. Seems I have to do some book reading myself, because I never came across this.
Hope you enjoy. Almost no one (0.01% ?) gets this right including the "experts" like Peter Attia. Very arcane stuff.
 
if Mast E is not driving my shbg into the teens?
That wasn't my claim. Mast or excess androgens could very well explain your lowered SHBG. My point was that Mast will not free up more T on absolute basis. Your free T proportional to T dose and set by your liver clearance of....free testosterone. Check out and read the resources I posted.
 
Hope you enjoy. Almost no one (0.01% ?) gets this right including the "experts" like Peter Attia. Very arcane stuff.
Yep, lots and lots of details like this go unnoticed and then dogma keeps getting repeated, with lots of people getting confused over why their truthful facts suddenly aren't so truthful. This is why I keep warning people of social media personalities who make use of the tactic to sell something new and original, most of the times confusing you by dismantling your beliefs/knowledge, then selling you total garbage. I did some book reading years ago and will take a break from reading and listening to experts and go back to good old textbooks on physiology.
 
Yep, lots and lots of details like this go unnoticed and then dogma keeps getting repeated, with lots of people getting confused over why their truthful facts suddenly aren't so truthful. This is why I keep warning people of social media personalities who make use of the tactic to sell something new and original, most of the times confusing you by dismantling your beliefs/knowledge, then selling you total garbage. I did some book reading years ago and will take a break from reading and listening to experts and go back to good old textbooks on physiology.
Great points. Most aren't reading the books on reversible protein binding wrt sex hormone transport in the body. Lol.
 
That wasn't my claim. Mast or excess androgens could very well explain your lowered SHBG. My point was that Mast will not free up more T on absolute basis. Your free T proportional to T dose and set by your liver clearance of....free testosterone. Check out and read the resources I posted.
Understood, I'll read what you have directed me to. What my ask is , I went back and looked I was off my a hair. 180.9 Bioavailable Test out of 197 Total T. That's seems amazingly high for it not to be influenced by something? My previous tests are no were close to 91% available when Mast was not in the mix. Again not trying to argue im trying to understand and maybe I just need to go read.
 

Attachments

  • 17557264454581747530953085057811.webp
    17557264454581747530953085057811.webp
    423.7 KB · Views: 4
Understood, I'll read what you have directed me to. What my ask is , I went back and looked I was off my a hair. 180.9 Bioavailable Test out of 197 Total T. That's seems amazingly high for it not to be influenced by something? My previous tests are no were close to 91% available when Mast was not in the mix. Again not trying to argue im trying to understand and maybe I just need to go read.
Bioavailable T is free T plus HSA (human serum albumin) bound.

Total T is the above plus SHBG bound T.

If you had your free T measurement using equilibrium dialysis it would be easier to discuss.
 

Sponsors

Back
Top