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[AllGoodThings]

Why do you guys bother splitting it up, with a half-life of 6 days?

Also, 250mcg?!

That's hefty af. Any RHR increase for you? Some people get it, some don't, and I haven't seen any correlating data on why.

While I no longer notice an appetite suppressive effect from it, when I initially started taking it I did notice it, and I found that after about the 4th day my appetite would start coming back. I was cutting down at the time, and wanted a more even appetite suppressing effect, so I just started doing Monday and Thursday shots at half the dose, which seemed to do the trick.

 

[powdered_toast_man]

Random thought, I would love to see a special run of injectable yk11 at an honest price. Any chance Primal could make that happen?

 

[Elektrobot]

12.5mg/week

dats a rot

 

[sionnach]

Yeah 250mcg eod equates to almost 1mg a week keeping me in good condition while able to up my calories as needed

Not really. 250mcg EOD only puts your peak at around 13k ng/DL while 1mg every 7 days gives a peak at ~22k ng/DL.

Phase 3 trials started beginners at 2mg/wk (45k ng/DL). And it's 1/20th as effective on GLP1 (gut motility and hunger suppression) as sema. You can still eat like a horse on reta. It's more for glucagon effects (ketosis and gluconeogenesis) than anything.

 

[sionnach]

While I no longer notice an appetite suppressive effect from it, when I initially started taking it I did notice it, and I found that after about the 4th day my appetite would start coming back. I was cutting down at the time, and wanted a more even appetite suppressing effect, so I just started doing Monday and Thursday shots at half the dose, which seemed to do the trick.

Why not add just add cagrilintide to even out hunger suppression?

 

[sionnach]

Random thought, I would love to see a special run of injectable yk11 at an honest price. Any chance Primal could make that happen?

Have you pinned yk11 before? Huge difference from oral?

 

[CHIEF M]

Not really. 250mcg EOD only puts your peak at around 13k ng/DL while 1mg every 7 days gives a peak at ~22k ng/DL.

Phase 3 trials started beginners at 2mg/wk (45k ng/DL). And it's 1/20th as effective on GLP1 (gut motility and hunger suppression) as sema. You can still eat like a horse on reta. It's more for glucagon effects (ketosis and gluconeogenesis) than anything.

Ahhh ok I got ya maybe I tell coach up the dose but I seem to get full quicker and also get burps and acid reflux from time to time had to add betaine and Ala in with meals

 

[sionnach]

Ahhh ok I got ya maybe I tell coach up the dose but I seem to get full quicker and also get burps and acid reflux from time to time had to add betaine and Ala in with meals

That's what's coolest about reta IMO - you don't feel full just because your stomach and guts are moving slower, you also feel full because your body's constantly making all the ketones and glucose you need, 24/7 (as long as you're hitting minimum protein goal). Pretty fuckin neat body hack.

 

[Smokeythabear]

Random thought, I would love to see a special run of injectable yk11 at an honest price. Any chance Primal could make that happen?

I asked him for this as well. The injectable at 5-10mg once or twice a day is supposed to be much more efficacious than oral. I’d love to see a reasonably priced 10ml vial at 50mg/ml

 

[powdered_toast_man]

Have you pinned yk11 before? Huge difference from oral?

I haven't. Never foubd a reliable/affordable source.

But I know there's concerns out there about if it's orallly bioavailable at all, and if it metabolizes into a nonbeneficial compound before reaching your system.

That makes me not want to try it orally at all, but I would love to give an injectable a run.

 

[Bandern]

All my homies love PP (primal pharma)

 

[Primal_Pharma]

Why do you guys bother splitting it up, with a half-life of 6 days?

Also, 250mcg?!

That's hefty af. Any RHR increase for you? Some people get it, some don't, and I haven't seen any correlating data on why.

No RHR issues at all, brother. Took me about 6–8 months to build up to this dose and I’ll be tapering off soon. Never been leaner and my bloods have never looked cleaner.

 

[Primal_Pharma]

Random thought, I would love to see a special run of injectable yk11 at an honest price. Any chance Primal could make that happen?

Definitely a chance. Will check in with the team tomorrow and see what we can do

 

[powdered_toast_man]

Definitely a chance. Will check in with the team tomorrow and see what we can do

id be all over it

 

[sionnach]

Never been leaner and my bloods have never looked cleaner.

Same. Reta is fucking gold. Bioglutide may blow it out of the water though. Looking forward to seeing some trial data.

 

[JBird99]

Always open to any and all suggestions, especially if there’s enough interest

Shit even if you made a special batch of it I’d be willing to pay for it just for the convenience I am an ignorant mofo when it comes to this so any convenience I’m willing to pay for. Haha

 

[readalot]

ignorant mofo

You gonna make a new member intro?

 

[readalot]

Shit even if you made a special batch of it I’d be willing to pay for it just for the convenience I am an ignorant mofo when it comes to this so any convenience I’m willing to pay for. Haha

Learn proper forum etiquette.

First, this begins by introducing yourself to the community with a thread in the New Member Introduction subforum. Tell us about yourself, your goals, your experiences, your expectations, etc. Use this subforum for your initial interactions with other members of the community.

 

[Oldhand]

Why do you guys bother splitting it up, with a half-life of 6 days?

Also, 250mcg?!

That's hefty af. Any RHR increase for you? Some people get it, some don't, and I haven't seen any correlating data on why.

I know you’re not asking me, but I pin Glow ED so I throw Reta in with it. For me, it’s easier than injecting 100iu (10mg) all at once.

When I was on a 2-4mg of Reta I did only pin it once a week. As the volume increased I started adding days. Once I got to 7mg it was easy to take it ED.

 

[JBird99]

You gonna make a new member intro?

I’ve been in the thread for a bit just haven’t been super active until recently but I can