I can donate some seros if it’s needed
MESO-Rx
Anabolic Steroids
The generic vs pharma GH discussion
- Thread starter justaphan
- Start date
@Ghoul can you refrain from posting all together any suggestion of sort as you ain't gonna contribute for shit about this whole thing?
And no we aren't gonna dilute 10/15IU with 2ml as no one here inject more than 0.5ml for 10/15IU of HGH.
As you are first completely detached from reality, second of all not able to put your action where your mouth is, please be a good sport and just shut it ok?
I hoped you would prove us all wrong and partecipate actively in such an interesting test that could maybe show some insight in stuff you keep blabbering since the dawn of humanity but nope you just showed your true face once again.
If you keep writing I'll just move this test to a private channel with only the ppl that fund the test invited as I can't stand your wall of text without any meaningful real contribution towards something concrete. You are just a fraud and I can't stand this kind of behaviour.
Yeah I can coordinate the testing and the funding no problem. I'm a bit busy in real life at the moment so I'll not be able to deal with Jano, what's best or worse to do etc. if you guys can plan that I'll mostly do my role as a facilitator in the background.
And I gotta say, I had a tons of respect for @Millard but the more I see your account posting left and right the more I feel something that I can't really explain towards Millard that let such a despicable user like you pollute this forum that I have loved so much during all these years. You are a cancer and no don't reply, don't say a word, you are gonna be ignored anyway, just prove me wrong for once and shut the fuck up
And no we aren't gonna dilute 10/15IU with 2ml as no one here inject more than 0.5ml for 10/15IU of HGH.
As you are first completely detached from reality, second of all not able to put your action where your mouth is, please be a good sport and just shut it ok?
I hoped you would prove us all wrong and partecipate actively in such an interesting test that could maybe show some insight in stuff you keep blabbering since the dawn of humanity but nope you just showed your true face once again.
If you keep writing I'll just move this test to a private channel with only the ppl that fund the test invited as I can't stand your wall of text without any meaningful real contribution towards something concrete. You are just a fraud and I can't stand this kind of behaviour.
Yeah I can coordinate the testing and the funding no problem. I'm a bit busy in real life at the moment so I'll not be able to deal with Jano, what's best or worse to do etc. if you guys can plan that I'll mostly do my role as a facilitator in the background.
And I gotta say, I had a tons of respect for @Millard but the more I see your account posting left and right the more I feel something that I can't really explain towards Millard that let such a despicable user like you pollute this forum that I have loved so much during all these years. You are a cancer and no don't reply, don't say a word, you are gonna be ignored anyway, just prove me wrong for once and shut the fuck up
Thank you for the offer. Very kind.
Given the logistics it's easier for one person to do this all. I'm tired of the fighting and respect everyone's busy schedules and time.
In terms of "better", we'd need a lot more than just a CD test to get to the bottom of this complex topic in addition to HPLC-MS/SEC...
Head to head comparisons of
(1) structure (2nd, 3rd)
(2) bioassay
(3) biological impurities like host cell proteins where impact may be very individual.
(4) ?
(5) ?
...
And we know already what's better. Question is really around good enough given individual's risk profile. And many have already answered that for themselves. The rest of this is just technically interesting and more academic to some.
Given this is UG, all this way past the 80/20 rule and surely takes the fun out of things for some folks. I get it.
I'll report back any info I find from lab and any results. Take care everyone.
AlexDavis43
Member
It's a fetish
*a poor IGF1 response is not a good indicator of poor quality GH but a good IGF1 response means it is good GH
**if the GH molecule was misfolded or sticky or whatever the fuck, it wouldn't increase IGF1
Spaceman Spiff
Subscriber
He just wants to be a fucking a leech and see what is tested. "Elite jerk off"
Spaceman Spiff
Subscriber
Spaceman Spiff
Subscriber
Maybe the Beetlejuice method hill get him to respond.
Filter, aggregates, immunogenicity, ifbb pro trainer
Filter, aggregates, immunogenicity, ifbb pro trainer
BamaCrazy
Banned
He’s here sulking. The loser is currently looking for our posts so he can down vote them all like a two year old. lol
Spaceman Spiff
Subscriber
I guess this NMR testing is horse shit and really doesn't matter. oh well. When some legit person wants to help coordinate the test with real experience, I am down to throw some cash
Banana Joe
Member
Good stuff, if there is way to test reliably for correct folding, that would hopefully put an end to this debate.
Coincidentally I researching this stuff for myself just a week ago. I didn't see it mentioned, but are you guys aware of that paper where they compared Chinese HGH to pharma?
I would have to check on my other device, for the Link/DOI, but maybe you guys already know about it anyway?
Based on my limited findings the sugar argument of Havens et al is also bullshit.
Coincidentally I researching this stuff for myself just a week ago. I didn't see it mentioned, but are you guys aware of that paper where they compared Chinese HGH to pharma?
I would have to check on my other device, for the Link/DOI, but maybe you guys already know about it anyway?
Based on my limited findings the sugar argument of Havens et al is also bullshit.
Spaceman Spiff
Subscriber
If there is, ghoul won't pay to test it.
There is nothing that compares both. Just theoretical, feels, and HPLC testing
Banana Joe
Member
I am pretty sure that was CD testing, but I would have to check again to find that paper again. I just glanced over the paper, but it seemed to confirm that Chinese HGH and pharma (could have been Sero or EU?!) were effectively comparable.
Spaceman Spiff
Subscriber
What paper? Are you talking about test results or an actual article?
Banana Joe
Member
Don't crucify me, if I misremember it, but it was an article/paper where they compared them. Some of the were authors were apparently Chinese, but it looked legit on first glance. Will try to post the link when I get to check other device.
AlexDavis43
Member
Thanks. I'd like to take a look.
Spaceman Spiff
Subscriber
not gonna crucify. would be interesting to see some solid info
Banana Joe
Member
I am afraid I have used Perplexity in private tab or whatever, as I can't find that thread in my list.
I doubt this help finding that paper, if What I (think) to remember was:
- I looked into how to detect possible differences in pharma vs China rHGH
- Perplexity's answer was the 3D structure of the molecule, which led me to the term of "folding", I was previously unaware of.
- it also led me to different kinds of analysis than HPLC-MS, namely CD (I think...)
- the paper talked about comparing rHGH from Chinese facilities and Western ones.
- That the paper was rather recent, likely 2018 or later.
- It had authors with Chinese names, but there might also have been Western names on it. I just remember that, because my first thought was this was a doctored paper by the Chinese, but after a first glance it seemed legit.
- It might have been in relation to administering rHGH to children, but I could be mistaken, as my today's search results often had that as a focus.
I will keep looking through my browsing history, but I use so many devices and browsers, this will be like finding a needle in the haystack...
Maybe the above recollection will help to locate that paper, at a first glance it seemed like a key answer in the question of Pharma vs Chinese rHGH.
Sorry, that is all I present for now.
I doubt this help finding that paper, if What I (think) to remember was:
- I looked into how to detect possible differences in pharma vs China rHGH
- Perplexity's answer was the 3D structure of the molecule, which led me to the term of "folding", I was previously unaware of.
- it also led me to different kinds of analysis than HPLC-MS, namely CD (I think...)
- the paper talked about comparing rHGH from Chinese facilities and Western ones.
- That the paper was rather recent, likely 2018 or later.
- It had authors with Chinese names, but there might also have been Western names on it. I just remember that, because my first thought was this was a doctored paper by the Chinese, but after a first glance it seemed legit.
- It might have been in relation to administering rHGH to children, but I could be mistaken, as my today's search results often had that as a focus.
I will keep looking through my browsing history, but I use so many devices and browsers, this will be like finding a needle in the haystack...
Maybe the above recollection will help to locate that paper, at a first glance it seemed like a key answer in the question of Pharma vs Chinese rHGH.
Sorry, that is all I present for now.
rockyraccoon
Member
Was it one of these?
The pharmacokinetic and pharmacodynamic properties and short-term outcome of a novel once-weekly PEGylated recombinant human growth hormone for children with growth hormone deficiency - PMC
To investigate the pharmacokinetics (PK) and pharmacodynamics (PD) of Y-shape branched PEGylated recombinant human growth hormone (YPEG-rhGH) and evaluate its short-term efficacy and safety in children with growth hormone deficiency (GHD). A total ...
pmc.ncbi.nlm.nih.gov
Compares Chinese pharma vs Norditropin.
Last edited:
Spaceman Spiff
Subscriber
Folding eh? @AlexDavis43
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