HGH sleep issues

[400degrees]

About a month in on ugl GH, 4iu every night before bed, 2hrs after dinner. First couple weeks it knocked me out all night. Past couple weeks I've been wide awake at 3am every night. Almost feels like a cortisol spike. Wondering if I should ride it out, switch to am, or if anyone has had the same experience or knows the possible science behind this regarding the gh interactions with prolactin, progesterone or adrenals.

 

[hungryalways]

I've found GABA pills to help a little. You need to take a lot though. Like a few grams. Xanax is saved for special occasions when I have true insomnia.

Interesting. I wonder if something like pregabalin could be a good stopgap while running HGH, although I hear that can also be quite tricky to come off, just nowhere near as bad as valium/xanax.

 

[Benf15harp]

ive moved my injections to morning post workout,,

This is the way!

 

[songsofpyramids]

I got a buddy doing 3x a week injections and he swears by it now. I’m going to try a cycle of it.

 

[The Answ3r]

Ever since I switched my HGH shots from evening to morning, my sleep’s been way better. Now I take 4iu right after waking up, and it’s been smooth sailing at night.

If anyone’s dealing with sleep issues, it might be worth trying the same. Or at least avoid pinning it right before bed - try doing it 2–3 hours earlier instead. Little timing tweak, big difference.

 

[Black Beard]

Sleep is messed up on as little as 1IU/day and awful on 2IU. No low carb.

Have you tried different sources for GH or only the same source?


Oddly enough, different sources can "feel different" for GH.

 

[Ghoul]

Have you tried different sources for GH or only the same source?


Oddly enough, different sources can "feel different" for GH.

Not really odd. There are far more potential differences between batches of rHGH than HPLC-MS testing alone can detect.

 

[Ateam2023]

Not really odd. There are far more potential differences between batches of rHGH than HPLC-MS testing alone can detect.

View attachment 327280

ok i'll start filtering,,

 

[songsofpyramids]

Not really odd. There are far more potential differences between batches of rHGH than HPLC-MS testing alone can detect.

View attachment 327280

or heavy metals, endotoxin, etc. I found it pretty interesting learning about all the QA that goes into rHGH in Pharma. Misfolding is a huge concern in the literature and testing.

 

[Ateam2023]

or heavy metals, endotoxin, etc. I found it pretty interesting learning about all the QA that goes into rHGH in Pharma. Misfolding is a huge concern in the literature and testing.

Tbh the level of "mishaps" possible with hgh it really makes you wonder how efficient this ugl generic is really , I truely wish i could afford pharm hgh , but , i can only hope that the long term benefits outweigh the potential, ,

 

[Ghoul]

or heavy metals, endotoxin, etc. I found it pretty interesting learning about all the QA that goes into rHGH in Pharma. Misfolding is a huge concern in the literature and testing.

Purity only tells you the rHGH is chemically correct, not whether it's structurally correct.

It's like knowing a key has the correct notches, but it could be bent into the wrong shape, unable to fit the lock (receptor). There's just no way to know without additional types of testing like pharma does.

It's much more complicated than something simple like AAS.

I just had a real eye opener about Tirz, and the shortcuts that UGL labs can take that they think will never be discovered, knowing all we look at is "purity".

 

[hungryalways]

Have you tried different sources for GH or only the same source?


Oddly enough, different sources can "feel different" for GH.

2 sources, but neither pharma.

 

[bulldogmuscle118]

Ever since I switched my HGH shots from evening to morning, my sleep’s been way better. Now I take 4iu right after waking up, and it’s been smooth sailing at night.

If anyone’s dealing with sleep issues, it might be worth trying the same. Or at least avoid pinning it right before bed - try doing it 2–3 hours earlier instead. Little timing tweak, big difference.

try doing it 90 minutes before you eat maybe before cardio has given me the best results. I have been using it for 15 years

 

[Fattyone]

I’ve tried minutes before bed, hours before bed, split morning and night, and first thing fasted in the morning. Zero difference in sleep.

REM and deep sleep is done
Heart rate variability is way down
Pulse is up ~7bpm
Times waking is up
Recovery (on whoop) is lower as well.

That was with a few brands all below 5iu’s daily (never tried pharma).


I’m tempted to try 3x a week and see what that does. Unfortunately sitting on a decent amount lol

 

[hungryalways]

Unfortunately sitting on a decent amount lol

Same man. Fridge and freezer fully stocked. May just have to put up with the shitty sleep at some point!

 

[Ateam2023]

im trying to do my 5 ius post workout, very shortly my whole program is changing due to injury that will be addressed sooner than later, then i may go back to pre fasted cardio dosing, , as long as it gets in your system and you are consistent with dosing , i think you will reap the benefits, ,

 

[Lord Commander]

My sleep was shit before and still is shit on gh, gawdamnit, my nights go just like yours basically

Are you on trt with no HCG? I recommend using progesterone cream before sleep.

 

[Ateam2023]

i'm going to add this and see if it helps,

 

[Ghoul]

Since everyone's throwing darts at this common problem, including doctors with patients on legit gh therapy, without much luck, I'll put mine on the board.

The medical way this is addressed is to lower the dose and/or try morning injection.

The most likely potential causes seem to me to be:

-Fluid retention in soft tissues in the neck causing or worsening sleep apnea. Especially when combined with TRT.

-The impact of rHGH on the brain causing problems with GABA or overstimulation.

Morning dosing helps with both of those.

I recently learned the sides commonly associated with rHGH, like water retention, appear to be related to the intensity of the GH spike after administration.

The spike can be smoothed out by slowing absorption. This can be done by:

Injecting SubQ not IM. Lateral thigh fat is the location for slowest absorption. Lower abdomen is next slowest. Arm is fastest.

Increasing volume (lowering concentration) of the injection. The same dose in .5ml will absorb less quickly than .1ml.

Excipients can impact absorption speed. Polysorbate 80 speeds up absorption significantly, increasing the spike. We usually don't know what these ingredients are, but switching to another brand may help since it could have a different formulation.

It may not be enough, but may be worth a
try since nothing else seems to work.

 

[AlexDavis43]

i'm going to add this and see if it helps,

Be careful with that gaba. Take it on a weekend night first.

Could do nothing or could make you oversleep your alarm by hours.

 

[Ateam2023]

i have switched back to back to a.m fasted injection , i was doing post workout for a couple weeks , but (didn't like jabbing in the gym parking lot) lmao , but now just my 5 iu dose @0600 every morning moving forward , ,