MESO-Rx Sponsor STANFORD PHARMA PUBLIC SALE 10/24/21

[Stanfordpharma1]

I am grateful we were able to decouple the cloudiness issue from the bubbles. I have no data to disprove your >1% BA hypothesis on the cloudiness issue and appreciate you taking the time to share your observations and data.



Here are your flowers for working so diligently to resolve these questions for members. My offer stands and appreciate you.



Nothing next as far as I can tell. The idea that >=1% BA water can cause enough aggregation (or whatever is happening) to cause the cloudiness is an interesting one and just another experiment to add to the list for testing to see if Jano can pick up the cloudiness on his "dimer and related proteins" test.


You absolutely are and now members can be confident they should not be seeing bubbles when reconstituting properly. Thank you.



Best wishes to you Stan and we can DM about the reimbursement. Thanks again for your time.

No need for reimbursement. Just being playful about the flowers. Happy to do such.

 

[readalot]

Nothing next as far as I can tell. The idea that >=1% BA water can cause enough aggregation (or whatever is happening) to cause the cloudiness is an interesting one and just another experiment to add to the list for testing to see if Jano can pick up the cloudiness on his "dimer and related proteins" test.

Related...

https://pmc.ncbi.nlm.nih.gov/articles/PMC4312256/

See Fig. 2

I'll see if I can find similar studies with somatropin.

 

[readalot]

Here we go, early work by Genentech.

https://www.sciencedirect.com/science/article/abs/pii/0378517396045772?via%3Dihub

10 mg/ml (~1%) loading. Would be interesting to see higher loadings of the preservatives.

As determined by various methodologies, most of the phenolic compounds caused rhGH aggregation, especially at high concentrations. Stress studies under freezing, high-temperature incubation, and agitation suggest that the destabilizing influence of the compounds tested increases in the order of benzyl alcohol < phenol × resorcinol < catechol < meta-cresol < 2-chlorophenol. Non-aromatic alcohols, except 2,6-dimethylcyclohexanol, have a much less adverse effect. Determination of the thermal transition temperature by microcalorimetry studies also reflected this trend. From our study, we conclude: (1) the phenolic additive-induced rhGH aggregates were held by non-covalent forces; (2) no significant physical binding occurred between the protein and these compounds; (3) the aggregation tendency of the phenolic compounds failed to correlate with their hydrogen bonding strength; (4) the presence of a phenolic additive caused conformational changes in rhGH's structure; (5) the effect of these phenolic compounds on rhGH aggregation decreased at high and low pHs.

Thanks for the education @Stanfordpharma1 and very helpful discussion.

Gently reconstitute your vials folks. Read the insert for Zomacton or Omnitropin. Don't shoot the water stream violently on the puck.

 

[glpfun]

Can we get one of those subscription box services where you just send us random steroids every month

 

[Stanfordpharma1]

Can we get one of those subscription box services where you just send us random steroids every month

Looking like steroids will be a thing of the past. We're going back to creatine and bcaa's. LoL.

 

[QuadFather]

Looking like steroids will be a thing of the past. We're going back to creatine and bcaa's. LoL.

Dat der frog tech making a comeback???

 

[BamaCrazy]

Looking like steroids will be a thing of the past. We're going back to creatine and bcaa's. LoL.

Nanotech injections that bestow superpowers would be much cooler. Forward not backwards. Send the price list. lol

 

[QuadFather]

Nanotech injections that bestow superpowers would be much cooler. Forward not backwards. Send the price list. lol

Speaking of superpowers lifting buddy told me how the hell did my bench go up 100 pounds in two months, I said sometimes you get knocked on the head and you get superpowers it happens all the time read a comic book or something

*i take frog tech*

 

[Ghoul]

This is a customer base that appreciates a premium product. You're going to use a needle to reconstitute anyway, may as well use these. 40¢ for large gauge low pressure, pressure venting, sidewall directed flow without coring the stopper.

So when that vacuum pressure sucks the BAC it won't hit your rHGH like a fire hose.

 

[Sicsemptyran]

Looking like steroids will be a thing of the past. We're going back to creatine and bcaa's. LoL.

but I thought this HappEnS EvERy YEar?!?

(Not saying you said that, just laughing about everyone who did)

 

[glpfun]

I put the reconstitution needle in at an angle so it hits the wall of the vial and also hold the plunger back

 

[QuadFather]

I put the reconstitution needle in at an angle so it hits the wall of the vial and also hold the plunger back

Common sense I’d assume… I was thinking about saying this, it’s actually taking me more time to type this response sometimes I literally feel my IQ going down when I login

 

[FastBun]

You absolutely are and now members can be confident they should not be seeing bubbles when reconstituting properly. Thank you.


So not like lobster attck on the vial???

 

[readalot]

You absolutely are and now members can be confident they should not be seeing bubbles when reconstituting properly. Thank you.


So not like lobster attck on the vial???

#dontabusethepuck

 

[glpfun]

but I thought this HappEnS EvERy YEar?!?

(Not saying you said that, just laughing about everyone who did)

I heard people in the US have started getting oils again from Chinese vendors so someone has raws or it’s old stock

 

[FastBun]

I heard people in the US have started getting oils again from Chinese vendors so someone has raws or it’s old stock

I think is old stock… before the shut down oil shipping…

 

[readalot]

I heard people in the US have started getting oils again from Chinese vendors so someone has raws or it’s old stock

Some Chinese vendors never stopped moving oils, just raws. It's a big world out there.

 

[SkankHunt]

Common sense I’d assume… I was thinking about saying this, it’s actually taking me more time to type this response sometimes I literally feel my IQ going down when I login

It is common sense. This forum is full of fucking retards now.

 

[readalot]

It is common sense. This forum is full of fucking retards now.

And not one like. I'm deeply hurt.

 

[Sicsemptyran]

I think is old stock… before the shut down oil shipping…

Absolutely, I think it’s just them trying to squeeze profit out of the raws that remain. Make more selling it as oil than raws.