Ghoul
Member
Like a self-service biopsy with every injection.
MESO-Rx
Anabolic Steroids
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- Thread starter Stanfordpharma1
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Like a self-service biopsy with every injection.
You will only know the damage you've done to your arteries if you get a calcium score. You can't reverse plaque. I had no clue until I got one last year and had calcification in 2 arteries. There is no way to know unless you have the test or symptoms (and symptoms usually mean stenosis). I had a battery of tests done - EKG, echo, holter, stress, carotid and they are all normal but the fact is that the calcification level remains. Many have this who have abused steroids (even if they 'fix' the diet and 'fix' the cardio - both of which may not even matter much for preventing ASCVD when abusing AAS) and they don't know.
Ghoul
Member
Another reason why I think at some point in the future GLP use while using AAS will be standard practice, even at low non-appetite suppressing doses, for its direct effect on blood vessels for endothelial protection to counteract this risk.
GLP-1 receptor agonists and atherosclerosis protection: the vascular endothelium takes center stage - PubMed
Atherosclerotic cardiovascular disease is a chronic condition that often copresents with type 2 diabetes and obesity. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are incretin mimetics endorsed by major professional societies for improving glycemic status and reducing atherosclerotic...
pubmed.ncbi.nlm.nih.gov
(TLDR: GLPs provide protection against plaque buildup beyond what would be expected from weight loss and glucose control. Though the direct mechanisms are not yet entirely understood, the impact is observable.)
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If so could do it all over again I would have used statins and never ever do a dirty bulk with orals.
That being said, this is Stan's product thread and he chimed in on my question and it was answered and appreciated.
Ghoul
Member
FYI, if you have a BMl above 26, the CVD you describe is an FDA approved indication for Wegovy(semaglutide), to prevent it from progressing, and covered by about 70% of insurance policies now.
QuadFather
Member
I never tried glp due to being told it’s the same as the saliva of the “GILA monster lizard” and it causes many issues if bit by that lizard and near guaranteed thyroid tumor/issues after a year of usage? Please correct me brother that’s the only thing preventing me from trying it
Ghoul
Member
That is absolutely false, with enormous retrospective studies of ~150,000 long term GLP users there's no indication of any meaningfully higher risk of thyroid cancer.
Ozempic And Wegovy Don’t Pose A Substantial Thyroid Cancer Risk, Study Suggests
Participants taking popular diabetes and weight loss drugs called GLP-1s were compared to those taking two other types of diabetes drugs, and the researchers found no substantial increase in thyroid cancer risk in the GLP-1 patients.
www.forbes.com
I recall reading an interview with a member of the Wegovy development team who said his one regret was that they agreed to the "thyroid cancer" warning in the "Monogram" (FDA required drug info leaflet.
Early on, docs were required to check for existing thyroid cancer before prescribing but that was dropped as it became apparent it was unnecessary.
Out of an abundance of caution, those with existing thyroid cancer are advised to avoid GLPs. GLPs increase growth hormone levels so, like all drugs that do that, higher GH may accelerate existing cancer, though the effect hasn't appeared in the stats at all (overall it significantly reduces cancer risk).
"Semaglutide significantly improved HbA1c and body weight in treatment-naive patients with type 2 diabetes compared to placebo. The safety profile was consistent with the GLP-1 receptor agonist class, with no significant risk for thyroid cancer."
accidentaljedi173
Member
Hey @Stanfordpharma1 , I know your slammed but any chance of tren a being added to the mct line eventually?
Thank you!
QuadFather
Member
no danger with Glp usage, brother?
I've been micro-dosing for a month now and the results have been pretty amazing.
Savagesteve
Member
Pretty wild you mention this as I had it done recently. Multiple abnormal EKG’s had me get the test to check the calcium build up. (My primary doesn’t know for sure that I use gear). Been blasting and cruising probably 8 years at the time and I had zero percent calcification/blockages.
I'll try and get that done in the next few days. Check with me Tuesday.
glpfun
Member
That made you not want to try it? Gotta get GILA gains. I guess the thyroid part is concerning but you could turn into a super hero called GILA GUY
accidentaljedi173
Member
You the man, but you already knew that
BamaCrazy
Banned
Compared to Tirz I found I can eat through Reta’s suppression with not much effort at all. On Tirz I could not.
chmuse
Member
Low dose tirz, you get the inflammation benefits and the weight loss. Great for liver and heart health. Would most likely make it more difficult to eat though.
If you don't have pre-existing tachycardia issues and don't mind that it's not approved yet, reta. But they are still studying cardiac side effects and there's no consensus yet. It has the best weight loss and the lowest appetite suppression of the three current major glp-1's
Losing weight is far too easy for me. I have to work to stay above 200lb at 6ft. Work as in I have no appetite ever. If I ate when hungry I would only eat 1 meal a day. Been like that since I can remember. But the health benefits sound interesting!! I just can’t be eating 1 meal every other day lmfao
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