Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

[Sampei]

Could you please confirm the material identity on batches moving forward?

Bromobutyl Vial Stoppers Vs Chlorobutyl Vial Stoppers

Serum vial stoppers are readily available in bromobutyl and chlorobutyl rubber formulations for use in pharmaceutical and biological packaging.

www.xiangyiintl.com

Vial Rubber Stopper, Medical Rubber Stopper Manufacturer

We are pleased to deliver Rubber Stopper. Safe payment and on time deliver time will give you.

www.xiangyiintl.com

Serum Stopper| xiangyi

The rubber stopper protects the medicine from environmental influences and helps maintain the quality and safety of the medicine.

www.xiangyiintl.com

[Because XIANGYI is the manufacturer of the serum stopper, we can customize the color of the stopper, such as red serum stopper, gray serum stopper, pink serum stopper, Serum Stoppers in Red Natural Rubber, Gray Butyl, and Silicone, and we can customize the size of the serum stopper, such serum stopper with Straight Sided Plugs, 11mm, 13mm, and 20mm, serum bottle stoppers with Blow back finish, 20mm and 30mm.]

Silicone is not good and it's useless anyway without a PTFE coating.

Butyl stopper is fine for not super long term storage.

 

[TheMoto]

Hey guys, I was provided a tracking # starting in YT and can’t figure out how to track. Normally I see on my informed delivery but nothing… input plz

17track.net

 

[goodyearwing1]

17track.net

Well… been in customs for 9 days I guess… normally all my stuff has shipping inside the states and 4-5 days total… any one seen this ?

 

[TheMoto]

Well… been in customs for 9 days I guess… normally all my stuff has shipping inside the states and 4-5 days total… any one seen this ?

It’s the holidays. Everything takes longer.

 

[Dkland]

Nope. Never. Feds are probably on the way. Hide out for a few years. We will send smoke signals when the coast is clear

 

[goodyearwing1]

It’s the holidays. Everything takes longer.

Factual…. Just a little different than “normal” is all…. Thanks for your reply sir

 

[goodyearwing1]

Nope. Never. Feds are probably on the way. Hide out for a few years. We will send smoke signals when the coast is clear

Thanks… I’m glad it’s a legal substance in my state

 

[Qingdao Sigma Chemicals]

Hey guys, I was provided a tracking # starting in YT and can’t figure out how to track. Normally I see on my informed delivery but nothing… input plz

17track website

 

[goodyearwing1]

17track website

Just wondering cause normally ships in the us… now from china so confused a little. Thanks

 

[BamaCrazy]

Just wondering cause normally ships in the us… now from china so confused a little. Thanks

It’s an international order, right? If you enter your tracking number into parcelsapp.com you might be provided a different USPS tracking number called Last Mile Tracking. If the only number you were provided is the USPS # you can manually add it to Informed Delivery.

 

[RedSwingline]

Silicone is not good and it's useless anyway without a PTFE coating.

Butyl stopper is fine for not super long term storage.

I have used silicone stoppers for years and have never detected a problem with them deteriorating. That is not to say it’s not happening, but I have not Visually seen any deterioration. When googling it, I don’t see anything about BA or BB causing any issues. I am not saying it does not happen somehow but I can’t seem to find documentation saying not to use it.

 

[HB_22]

Has anyone tried ipamorelin 300mcg every 2 hours? and between 250mcg and 500mcg there is no more GH release?

Where you got this nonsense from? Inject it every 3 hrs and the more ipamorelin you add the higher the gh spike.

 

[NiMa]

Factual…. Just a little different than “normal” is all…. Thanks for your reply sir

Well… been in customs for 9 days I guess… normally all my stuff has shipping inside the states and 4-5 days total… any one seen this ?

Christmas gifts, Christmas holidays, Black Friday orders, returns, New Year holidays... it's taking longer everywhere at the moment.

 

[readalot]

Benzyl Benzoate turns silicone to goo and causes chemicals to leech into the solution making it unsuitable.

PTFE coated bromo or chloro butyl rubber is the ultimate non-reactive stopper, especially for long term storage.

Silicone is not good and it's useless anyway without a PTFE coating.

Was interested in Tracy's thoughts. I had thought they were common for lyo vials.

I have used silicone stoppers for years and have never detected a problem with them deteriorating. That is not to say it’s not happening, but I have not Visually seen any deterioration.

https://www.permselect.com/sites/default/files/2019-09/Silicone_Chemical_Compatibility_Chart.pdf

To Ghoul's point. See benzol and benzyl group entries above.

https://www.kgk-rubberpoint.de/wp-content/uploads/migrated/paid_content/artikel/2324.pdf

 

[NiMa]

Where you got this nonsense from? Inject it every 3 hrs and the more ipamorelin you add the higher the gh spike.

Studies say otherwise. 100-250mcg is the dosage and anything above that will not more increase the GH Spike.

 

[Ghoul]

Was interested in Tracy's thoughts. I had thought they were common for lyo vials.

https://www.permselect.com/sites/default/files/2019-09/Silicone_Chemical_Compatibility_Chart.pdf

To Ghoul's point. See benzol and benzyl group entries above.

https://www.kgk-rubberpoint.de/wp-content/uploads/migrated/paid_content/artikel/2324.pdf

Shows BB in the worst category of silicone compatibility here as well:

Chemical Compatibility Chart | Applications| Jehbco Silicones

Silicone rubber has excellent chemical compatibility with a wide range of materials, often providing and advantage over other materials with similar elastomeric properties. In particular, silicone displays outstanding chemical compatibility with water, aqueous and most chemically polar substances.

jehbco.com.au

 

[Rawbie]

Shows BB in the worst category of silicone compatibility here as well:

Chemical Compatibility Chart | Applications| Jehbco Silicones

Silicone rubber has excellent chemical compatibility with a wide range of materials, often providing and advantage over other materials with similar elastomeric properties. In particular, silicone displays outstanding chemical compatibility with water, aqueous and most chemically polar substances.

jehbco.com.au

Are you all referring to stoppers deteriorating from a bunch of stabs? Or rotting over time?

 

[RedSwingline]

Shows BB in the worst category of silicone compatibility here as well:

Chemical Compatibility Chart | Applications| Jehbco Silicones

Silicone rubber has excellent chemical compatibility with a wide range of materials, often providing and advantage over other materials with similar elastomeric properties. In particular, silicone displays outstanding chemical compatibility with water, aqueous and most chemically polar substances.

jehbco.com.au

Thanks for the info. Looks like I am going to changing out stoppers. I wonder why I’ve never seen damage. If I can find an old vial, I am going to take some photos to compare a year old stopper to a new one visually. Would this apply to <20% BB as well as 100% BB which is what I assume they tested it with.

 

[Ghoul]

Are you all referring to stoppers deteriorating from a bunch of stabs? Or rotting over time?

Rotting over time. I'm not sure how silicone holds up against repeated puncture coring particles vs synthetic rubber.

However, for peptides it's bad. Proteins stick to silicone forming a film coating,, and any particles created become aggregation magnets.

https://www.sciencedirect.com/science/article/abs/pii/S0022354920307802

 

[Ghoul]

Thanks for the info. Looks like I am going to changing out stoppers. I wonder why I’ve never seen damage. If I can find an old vial, I am going to take some photos to compare a year old stopper to a new one visually. Would this apply to <20% BB as well as 100% BB which is what I assume they tested it with.

I'm sure 20% will have an effect, how quickly who can say. You'd have to analyze the gear to determine what and how much leeched into it.

Obviously the longer the time, the more will migrate into the oil.

The chemical being extracted is polydimethylsiloxane, PDMS.

PDMS isn't particularly toxic orally.

PDMS is mildly toxic subcutaneously, and appears to build up in place, since the body has no means to break it down or flush it out.

PDMS that reaches the circulatory system is toxic and can be fatal in high doses.

The max acceptable limit for injectables is 93ug/day or about 1/10ml / day. That seems like a lot, but I'd rather keep it out entirely.

https://journals.sagepub.com/doi/10.1177/07482337221123368