Are protein hydrolysates worth it?

[master.on]

Hydrolysate refers to any product of hydrolysis. Protein hydrolysate has special application in sports medicine because its consumption allows amino acids to be absorbed by the body more rapidly than intact proteins, thus maximizing nutrient delivery to muscle tissues.[1]
Hydrolysate - Wikipedia

Protein hydrolysates in sports nutrition

 

[Xlgx]

I like it for pre and or pwo. Almost zero digestion and pure assimilation.

 

[ALPHAM1]

Supposedly they are of the highest quality and maximize absorbtion. For pre and post workout that's all I use...when I add in extra protein during a training cycle I'll just use any normal protein for other times of the day. Helps save some money, and you get the good stuff when your body needs it.

 

[Docd187123]

If you want a more POORLY digested protein, a less efficiently absorbed protein, a protein that is more likely to be used for energy, and a protein that is more used by the gut than by muscles then go ahead and use hydrolysate protein. If you want a better choice, stick to regular, intact, proteins.



Deglaire et al. Hydrolyzed dietary casein as compared with the intact protein reduces postprandial peripheral, but not whole-body, uptake of nitrogen in humans. Am J Clin Nutr. (2009) 90(4):1011-22.

BACKGROUND: Compared with slow proteins, fast proteins are more completely extracted in the splanchnic bed but contribute less to peripheral protein accretion; however, the independent influence of absorption kinetics and the amino acid (AA) pattern of dietary protein on AA anabolism in individual tissues remains unknown. OBJECTIVE: We aimed to compare the postprandial regional utilization of proteins with similar AA profiles but different absorption kinetics by coupling clinical experiments with compartmental modeling. DESIGN: Experimental data pertaining to the intestine, blood, and urine for dietary nitrogen kinetics after a 15N-labeled intact (IC) or hydrolyzed (HC) casein meal were obtained in parallel groups of healthy adults (n = 21) and were analyzed by using a 13-compartment model to predict the cascade of dietary nitrogen absorption and regional metabolism. RESULTS: IC and HC elicited a similar whole-body postprandial retention of dietary nitrogen, but HC was associated with a faster rate of absorption than was IC, resulting in earlier and stronger hyperaminoacidemia and hyperinsulinemia. An enhancement of both catabolic (26%) and anabolic (37%) utilization of dietary nitrogen occurred in the splanchnic bed at the expense of its further peripheral availability, which reached 18% and 11% of ingested nitrogen 8 h after the IC and HC meals, respectively. CONCLUSIONS: The form of delivery of dietary AAs constituted an independent factor of modulation of their postprandial regional metabolism, with a fast supply favoring the splanchnic dietary nitrogen uptake over its peripheral anabolic use. These results question a possible effect of ingestion of protein hydrolysates on tissue nitrogen metabolism and accretion.

 

[RodgerThat]

If you want a more POORLY digested protein, a less efficiently absorbed protein, a protein that is more likely to be used for energy, and a protein that is more used by the gut than by muscles then go ahead and use hydrolysate protein. If you want a better choice, stick to regular, intact, proteins.



Deglaire et al. Hydrolyzed dietary casein as compared with the intact protein reduces postprandial peripheral, but not whole-body, uptake of nitrogen in humans. Am J Clin Nutr. (2009) 90(4):1011-22.

BACKGROUND: Compared with slow proteins, fast proteins are more completely extracted in the splanchnic bed but contribute less to peripheral protein accretion; however, the independent influence of absorption kinetics and the amino acid (AA) pattern of dietary protein on AA anabolism in individual tissues remains unknown. OBJECTIVE: We aimed to compare the postprandial regional utilization of proteins with similar AA profiles but different absorption kinetics by coupling clinical experiments with compartmental modeling. DESIGN: Experimental data pertaining to the intestine, blood, and urine for dietary nitrogen kinetics after a 15N-labeled intact (IC) or hydrolyzed (HC) casein meal were obtained in parallel groups of healthy adults (n = 21) and were analyzed by using a 13-compartment model to predict the cascade of dietary nitrogen absorption and regional metabolism. RESULTS: IC and HC elicited a similar whole-body postprandial retention of dietary nitrogen, but HC was associated with a faster rate of absorption than was IC, resulting in earlier and stronger hyperaminoacidemia and hyperinsulinemia. An enhancement of both catabolic (26%) and anabolic (37%) utilization of dietary nitrogen occurred in the splanchnic bed at the expense of its further peripheral availability, which reached 18% and 11% of ingested nitrogen 8 h after the IC and HC meals, respectively. CONCLUSIONS: The form of delivery of dietary AAs constituted an independent factor of modulation of their postprandial regional metabolism, with a fast supply favoring the splanchnic dietary nitrogen uptake over its peripheral anabolic use. These results question a possible effect of ingestion of protein hydrolysates on tissue nitrogen metabolism and accretion.

This is more informative then what I had to say... which is that it’s a croc of shit. The more your proteins been broken down outside of your body the worse it is for recovery inside you body IMO. Slab of steak requires so much time to break down in the body oh noooooooo! But it’s tasty as fuck and gonna be the best for your body so I mean win win?

 

[Docd187123]

This is more informative then what I had to say... which is that it’s a croc of shit. The more your proteins been broken down outside of your body the worse it is for recovery inside you body IMO. Slab of steak requires so much time to break down in the body oh noooooooo! But it’s tasty as fuck and gonna be the best for your body so I mean win win?

at my job we got a 30day dry aged 14oz ribeye...::NOMNOM

 

[mghoward74]

Hydrolysate refers to any product of hydrolysis. Protein hydrolysate has special application in sports medicine because its consumption allows amino acids to be absorbed by the body more rapidly than intact proteins, thus maximizing nutrient delivery to muscle tissues.[1]
Hydrolysate - Wikipedia

Protein hydrolysates in sports nutrition

Why are you using "wiki" for research information? There are other reliable sources to use..

Makes no sense!!!

 

[pitbull]

I am guilty of not buying isolates just because the regular stuff always taste better. I use protein shakes as a snack. So taste is important.

Damm now I want a Rib Eye steak

 

[master.on]

Why are you using "wiki" for research information? There are other reliable sources to use..

Makes no sense!!!

lol
Wiki just meant as a general intro on what hydrolysates are.

As for research
Absorption of Peptides. There is virtually no absorption of peptides longer than four amino acids. However, there is abundant absorption of di- and tripeptides in the small intestine.

The mechanism by which amino acids are absorbed is conceptually identical to that of monosaccharides. The lumenal plasma membrane of the absorptive cell bears at least four sodium-dependent amino acid transporters - one each for acidic, basic, neutral and amino acids. These transporters bind amino acids only after binding sodium. The fully loaded transporter then undergoes a conformational change that dumps sodium and the amino acid into the cytoplasm, followed by its reorientation back to the original form.
Absorption of Amino Acids and Peptides

So you'd better take your protein/hydrolysates/amino acids along some salt (to get the required Sodium)?

 

[RodgerThat]

So you'd better take your protein/hydrolysates/amino acids along some salt (to get the required Sodium)?

If you stand on your head while you do it absorption is proven to be 312% more effective. If you buy protein buy the one that tastes the best and fits your budget and if that so happens to be steak and bacon and chicken perfect if it’s a powder well then just get whatever fits your budget none of them beat real food and getting it in your body immediately after a workout doesn’t do shit anyways.

 

[CJames]

Do you believe in anabolic window and 30 minutes joke? Lmfao, if you have digestive issues then go for it but if you don't then save your money for chicken breast or isolate /concentrate protein.