SWALE and others

[rokkstaar]

Which steroids cause little to no shutdown of the HTPA? Winstrol, primobolan????

 

[MaxRep]

Which steroids cause little to no shutdown of the HTPA? Winstrol, primobolan????

Unless there are studies to show otherwise, and I don't remember coming across any, I don't believe any steroid can be used without affecting the HPT (hypothalamus-pituitary-thyroid) axis. I've read the studies where anavar at 2.5mg/day and dianabol at 15mg/day and of course Test, Deca and others are well documented to all affect the HPTA.

IMO, it's illogical to think a steroid could be used without affecting the HPTA. When a person understands the role of the hypothalamus, it's easy to see why all steroids affect the HPT axis. In simplest terms, the role of the hypothalamus is to maintain homeostasis within the body. Whenever anything from hormones to body temperature, to a hundred other things change, the hypothalamus acts to bring them back to the norm.

As one of its duties, the hypothalamus, through circumventricular organs (just one of its many monitoring methods) monitors substances, hormones, toxins, etc., within the blood. The detection of steroids tells the hypothalamus there's a reduced or no need for it to release GnRH. If there's no GnRH, the pituitary doesn't release LH or FSH and if they aren't released, there's no sperm or testosterone produced.

The above is somewhat simplified and there are shades of gray, meaning it's not always all or nothing.

Anyway, you can go ahead and try to fool your body, but it's very difficult to do. IMO, the popular method of trying to fool your body by taking x amount of x oral steroid early in the morning doesn't make the grade. And taking any injected steroid, thereby ensuring a constantly circulating steroid 24 hours a day, stands zero chance of being ignored and getting your hypothalamus to continue full release of GnRH. If you take enough to make any difference at all, it's also enough to alert your hpothalamus and start the reduction or shutdown process.

MaxRep

 

[rokkstaar]

SWALE..... what about you? What do you think?

Also I wasn't really asking which steroid caused no downregulation at all(we all wish there was such a thing). The second part of my question is "which one or ones would be the "more safe" ones". Meaning what can be taken with very little down regulation and allow for very quick recovery after say 4-6 weeks on. For example if someone took 50mg of winstrol a day for 6 weeks. Or for example if someone took 100mg of primobolan a week for 6 weeks. Or if someone took 20mg a day of dianabol for 6 weeks.

 

[buck]

Doesn't sound much like a HRT question.

 

[SWALE]

I'm with MaxRep...and buck.