Should you take lower dosages of SS-31 over a longer period of time or high doages for a short time?

[Proud Pangolin]

Well the question is basiacally in the titel.
Obviously high dosages for a longer period of time would be best. However as 10x50mg (=500mg) cost me like 330 bucks..... yeah you get the idea.

I could do 10mg for 50 days, 30mg for 16 days or 40mg for 12 days.

https://www.reddit.com/r/cfs/s/NRGClDtqS5

This guys claims that the high dosages of 30mg hat a permanent improving effect and 40mg is the dosage that is used in all the studys.

To complicate things further, that guy from reddit didnt took the 30mg every day but: "each time I started to feel normal again, I took another dose, until I had done 10 of these 30mg dosages."

So basically im left with 3 possible protocolls:
1.Low dose every day for a long time

2. high dose every couple of days (so instead of 10mg every day, i could take 30mg every 3 days)

3. high dosage every day for a short time.

There are arguments for both sides.
One may argue that people take SS-31 for a to short time and they have to take it for at at least 4 weeks

Others would argue, a high enough dosage is needed to pass a certain "threshold"


Has anyone tried SS-31 and/ or could share his opinion about this?

 

[Nidus]

I personally always loved longer duration at moderate doses -> 15mg for 3 Months and had an amazing experience overall. I do combine with with a bunch of other Mito supps and peps like Motsc though.

 

[nxckf]

Tried both. Didn’t notice anything tbh. Tried to make my $330 kit stretch. Then tried again pushing higher doses (30-40mg a day). Ran mots C after- might as well just inject BAC water. Maybe my mitochondria are just functioning fine but I noticed no benefit

 

[SmallTitsIRL]

Unless you have kidney/heart disease or any order disorder that you need SS31 to survive/recover, there's no reason to do 40-50mg daily, you'd be better off doing 1-5mg daily pre-workout/cardio with 1-5mg MotsC for the energy, fat metabolism and blood glucose benefits.

 

[level3]

Anecdotally I feel like most people who rave about SS-31 are older - especially people 50+. Or they have some serious medical condition, like the guy in your post. I tried it at 4mg/day for a month last year and didn't notice jack shit, but I'm in my mid 30's and probably didn't need it. Then I saw how all the scientific studies used doses like 10x that. Too expensive for me. Decided to bin it and maybe give it another shot in my 40's once I have many years worth of every other peptide I like in stock and dropping a grand on a mitochondria experiment feels worthwhile.

 

[Proud Pangolin]

Tried both. Didn’t notice anything tbh. Tried to make my $330 kit stretch. Then tried again pushing higher doses (30-40mg a day). Ran mots C after- might as well just inject BAC water. Maybe my mitochondria are just functioning fine but I noticed no benefit

so you didnt even notice something on higher dosages per day? Interesting

 

[BeardedGuy]

SS-31 5mg/day just made me tired. ‍

 

[touringsedan]

40mg/day was the only dose used on humans. If it worked lower, it would have been used lower.
Trials were 6 months and daily dosing was required to maintain effects, so it doesn't have permanent/repair mechanisms. You need to stay on the drug to keep improvements.

 

[Here2Learn]

The Mayo Clinic is running a private trial, read lots of posts from a guy in it, and they are working towards 100mg/day for a year. It is a study focused on those over 40 and their biomarkers. He said the binaries improvements have been impressive for everyone enrolled. It is not a blind study but sounds more like a you have enough money you donated to us we are going to invite you in kind of thing. Last I knew they were up to 60mg/day. I’ve titrated up to 20mg/day at this point, got there January 4th so almost a month. My first run I was exhausted all the time and had to tap out at 16mg/day. From what I understand, those over 40 ss-31 is the way to go and those under mots-c is the way to go. I am sure there are outliers but a general rule of thumb.