What do you need to know about mass spectrometry?
On routine hormonology, liquid chromatography mass spectrometry (LCMS) is now an established technique for androgen, urinary cortisol and metanephrine assay. It has the undeniable advantage of great analytical specificity, but with sensitivity that clearly depends on financial investment in a very high-end spectrometer.
We describe the general principles of LCMS and the routine applications so far developed in hormonology. The purpose is to familiarise endocrinologists with the techniques under development and their pros and cons.
Corcuff JB, Ducint D, Brossaud J. What do you need to know about mass spectrometry? A brief guide for endocrinologists [published online ahead of print, 2020 Apr 11]. Ann Endocrinol (Paris). 2020;S0003-4266(20)30059-7. doi:10.1016/j.ando.2020.03.021 What do you need to know about mass spectrometry? A brief guide for endocrinologists - ScienceDirect
On routine hormonology, liquid chromatography mass spectrometry (LCMS) is now an established technique for androgen, urinary cortisol and metanephrine assay. It has the undeniable advantage of great analytical specificity, but with sensitivity that clearly depends on financial investment in a very high-end spectrometer.
We describe the general principles of LCMS and the routine applications so far developed in hormonology. The purpose is to familiarise endocrinologists with the techniques under development and their pros and cons.
Corcuff JB, Ducint D, Brossaud J. What do you need to know about mass spectrometry? A brief guide for endocrinologists [published online ahead of print, 2020 Apr 11]. Ann Endocrinol (Paris). 2020;S0003-4266(20)30059-7. doi:10.1016/j.ando.2020.03.021 What do you need to know about mass spectrometry? A brief guide for endocrinologists - ScienceDirect
