It's not great, and usually a sign of something gone wrong in the lyophilization process. "Ugly pucks". or "bad cake" are the industry terms.
That said, 99% of the time we don't know wtf we're actually injecting regardless of test results (since every vial could be different), and there's nothing about that which would mean it's "ruined", especially if it still has vacuum.
Just reconstitute, preferably with 3ml. See if it has visible particles after 15 minutes, which is a clue about "damage".
Either way filter it and use it as normal, and it'll probably be fine, worst case a little less potent.
PS : The main possible problem here is more surface area exposed to residual oxygen, which can oxidize the rHGH. Oxidized rHGH unfolds more easily after reconstitution, creating aggregates (visible or invisible). With a solid puck it mostly affects the top layer, but in pieces oxygen could contact a lot more. If you have this and no vacuum it'll be a lot worse because there's much more oxygen in the vial without vacuum.
