How do people lose control of estrogen on a blast of test more than 5 weeks into it?

[marsupial]

It's 5 half lives (i.e. roughly 4 weeks) for test E/C to be at steady state, and presumably very shortly after that, test levels will also be relatively stable and unchanging aside from peaks/troughs within the supraphysiologic interval that the dose provides. Yet I've seen people say they lost control of estrogen symptoms on week 8 or something like that.

 

[buck]

The pathways for removing estrogen can change. Liver not functioning as well, age etc. The body is a complex system that is not fully understood.